Patrickthebiosteamist

@patbiosteamist.bsky.social

Engineer & Scientist. Breaks down Covid papers & data. Masked fitness series. All views expressed are my own, I speak from a US perspective. Not a Covid researcher nor a Covid scientist. youtube.com/@patrickthebiosteamist?si=FoWeCh6fdBWY5jEt

Vaccination reminder. Updated Covid-19 and flu vaccines are available. I was able to get the new updated Moderna Covid-19 vaccine (first time diverging from Pfizer for that). Got it in opposite arms, keeping my covid and flu arms the same. Some research shows this can help enhance responsiveness

Covid-19 new Moderna vaccine for 2026 arm shown here, flu vaccine in other arm not shown.

Weird combination of errors today - computer went into an auto do not disturb mode (which I never set, so must have been an update thing) , which blocked signal to the 3d printer. So wasted about 45 minutes troubleshooting something that I only saw inadvertently from my computer’s daily log.

It’s important to note that the absence of counting the Pennsylvania 2 measles deaths is coming from the same playbook they used for Covid to downplay it. The died “as a result of measles” or “died but happened to die with a measles infection”.

Adding in another thing you can do - I was on the CDC NWSS page today (the color map shown), and they are doing a survey currently on that page. I wrote a paragraph explaining these types of things with reccs of what to do better in the very last part of the survey. Something to try at least 🤷🏻‍♂️

Mike Hoerger, PhD, MSCR, MBA@michael-hoerger.bsky.social · 2w ago

The CDC recently downshifted current and historical COVlD levels into lower categories. For example, 6 of the 8 states normally classified as High or Very High have been downshifted to "Moderate." This is Part 2 in our series on the CDC "Bluewashing" ethics crisis.

The CDC recently downshifted current and historical COVlD levels into lower categories. For example, 6 of the 8 states normally classified as High or Very High have been downshifted to "Moderate." This is Part 2 in our series on the CDC "Bluewashing" ethics crisis.

Mike Hoerger, PhD, MSCR, MBA@michael-hoerger.bsky.social · last mo.

🚨BREAKING 🦠 On Friday, the US CDC arbitrarily shifted higher COVlD levels into lower categories depicted with cooler colors. Much of what was Very High is now "High." What was High is now "Moderate" or "Low." Low is "Very Low." 1/

Here’s a take from another person (with more credentials), further explaining what I had been documenting for the past few years, ever since the CDC shifted to viral activity levels. I’ll tag the posts I’ve made or link the YouTube videos under this.

Mike Hoerger, PhD, MSCR, MBA@michael-hoerger.bsky.social · last mo.

🚨BREAKING 🦠 On Friday, the US CDC arbitrarily shifted higher COVlD levels into lower categories depicted with cooler colors. Much of what was Very High is now "High." What was High is now "Moderate" or "Low." Low is "Very Low." 1/

After months of presumably low Covid-19 levels - barring some sort of signal attenuation from new variants (confounding variable) - we are starting to see some early activity from the Kinston, North Carolina facility. Also, 99% chance growing Covid activity from ED visits.

WastewaterSCAN Covid-19 signal chart of the 147 active sites still remaining. Highest activity currently in Kinston, North Carolina as of 14 August 2026Purple everywhere on the ED visit map, showing growing/increasing trends of COVID-19 ED visits, as of 14 August 2026

The new names of what is currently circulating in the past 5 weeks: PQ.16.1.1 at 30% RF.5 at 11% RK.1 at 11% RW.1.1 at 7% SW.2.1 at 6% BA.3.2.2 (mostly RE.1*) at 6% RV.1 at 5% XFG.14.1.1 at 2% under 2% and over 1% PJ.2.1, XFZ.4.1, SZ.3.1, TB.1,XFG.6.13 As predicted a dozen of branches survived.

Mike Honey@mikehoney.bsky.social · last mo.

Here's the latest variant picture for the United States, to mid-July. XFG.* "Stratus" remained dominant but fell as low as 33% before rebounding to finish at 52%. #COVID19 #SARSCoV2 #USA 🧵

Jesus Christ. Doing a new housing application and to verify I am me (who is filling out the form post-scanning my government ID), I had to do a prisoners photo set of front, left, and right side photos in the application portal. What the literal fuck…

Fourteen more PJ.2.1 wastewater detections. It is dominant in many sites. NYC (8), Maui (2). Maine, Virginia, Florida and DC. No obvious uptick in cases in any of these places that I could find though.

I ve said it would have been fast, BB+4 variants rapidly taking over worldwide: PQ.16.1.1 and SZ.3.1 both NB.1.8.1+420N dominating in HK, SW.2.1 outcompeting everything else in Mexico and leading by far in California over all the other new variants (RW.1.1,SV*,RV* ,RF.5)

This chronic-infection variant now has a name: PJ.2.1. You can see how divergent it is from other current lineages in the @neher.io/Roemer BA.2.86 tree below. It originated in Ontario but has been detected in wastewater by @solidevidence.bsky.social in New York, Florida, Alabama, & Utah I think. 1/3

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Ryan Hisner@ryanhisner.bsky.social · 2mo ago

A mysterious, unusually diverse saltation lineage descended from KP.3.1.1 (last seen early 2025) has circulated at a low level for ~8 months in Ontario (see 🧵 on next post). Seemed a local anomaly, but @solidevidence.bsky.social just spied a weird spike in NYC wastewater—& it's the same one! 1/14

ORF6 is a SARS-2 protein that shuts down traffic between the nucleus & cytoplasm in host cells, inhibiting host mRNA export & immune responses. But in all variants since early 2023, ORF6's abilities are hampered by the ORF6:D61L mutation. Two newish ORF6 observations.... 1/15

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This is a great concept for people to understand - it’s not always about the # of mutations of a variant, but how the mutation impacts the protein structure itself. Sometimes a single point mutation/deletion can change the shape of a protein. Like a load bearing wall, it shifts the foundation

Ryan Hisner@ryanhisner.bsky.social · last yr.

The effect of even a single AA deletion in this area can have major effects in distant spike regions. ∆S31, in KP.3.1.1 and LP.8.1, seems to have a substantial effect on spike cleavage. FCS-weakening mutations do great in JN.1 without ∆S31, but terrible when ∆S31 is present. 13/16