Karson Chrispens
@karsonchrispens.bsky.social
UCSF Biophysics PhD Student. Looking at proteins @fraserlab.bsky.social. Pronouns he/him.
Excited to present sampleworks: a modular platform for generating biomolecular conformational ensembles by coupling AI structure predictors to experimental data. Our first publication of @diffuseproject.bsky.social, led by @karsonchrispens.bsky.social + Marcus Collins. thestacks.org/publications...
sampleworks: A Modular Platform for Experimentally Guided Biomolecular Ensemble Generation
thestacks.org
Excited to share Sampleworks led by @karsonchrispens.bsky.social with @diffuseproject.bsky.social. It's a modular framework connecting structure predictors to experimental data and guidance methods. Swap predictors or guidance methods. All open and made to be built upon. t.co/fvNHH3gfVu
https://diffuse.science/posts/sampleworks/
t.co
Hi bluesky scientists! Recently, @stephanieaw.bsky.social @fraserlab.com held a workshop at UCSF to discuss methods for modeling heterogeneity in structural biology (conformationalensembles.github.io).
PREreview of “Boltz-2: Towards Accurate and Efficient Binding Affinity Prediction”
Authored by Karson Chrispens and 2 other authors
prereview.org