MHR | Foundations of Reproductive Science

@mhr-reprodsci.bsky.social

MHR leads the way in research focused on the foundational and translational mechanisms of mammalian reproduction. @ESHRE @eshre.bsky.social @OUPAcademic @OxfordJournals

๐Ÿ”ฌ How do microRNAs coordinate human placental development? A new study in @MHR_Journal maps miRNAโ€“gene co-regulation across pregnancy: ๐Ÿ”น 1st tri: Maternal circulating EVs lead ๐Ÿ”น 3rd tri: Placental tissue leads ๐Ÿ”น Linked to TGF-ฮฒ & birth weight ๐Ÿ“– academic.oup.com/molehr/advan...

The miRNA-coordinated synergism for placental gene regulation throughout pregnancy

Abstract. The regulation of gene expression by microRNAs (miRNAs) is essential during development. However, it is necessary to move beyond individual miRNA

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๐Ÿšจ New in MHR: A promising step forward in non-hormonal contraception! Justine Fischoeder, Carla Ritagliati, and team just published a new Concise Communication on assessing the efficacy of ADCY10 inhibitors in cervical mucus. ๐Ÿงฌ ๐Ÿ”— Read here: academic.oup.com/molehr/artic... ๐Ÿงต๐Ÿ‘‡

Assessing efficacy of ADCY10 inhibitors in cervical mucus

Abstract. Male fertility depends on sperm motility, which enables sperm to traverse the female reproductive tract to the site of fertilization. Soluble ade

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๐ŸŒŸ EDITOR'S CHOICE & Open Access! ๐Ÿ”“ The human endometrium regenerates monthly, but this is linked to pathologies like endometriosis. This new review by Subramaniam et al. unpacks the somatic mutation landscape & the need for new in vitro models. ๐Ÿ“– Read: academic.oup.com/molehr/artic...

Somatic mutations in endometrial epithelium: biological insights and emerging in vitro models

Abstract. The human endometrium is a complex, dynamic, and poorly understood tissue involving monthly cyclical regeneration likely from adult stem/progenit

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