๐ Meet MHR Associate Editor Pablo E. Visconti (@UMassAmherst)! ๐ฌ Research: Sperm capacitation, fertilization & embryo development. ๐ก Why MHR? "Fast reviews & no charges to submit or publish!"๐ ๐ฅ Board: bit.ly/MHR_Board ๐ Submit: bit.ly/MHR_Submissions
MHR | Foundations of Reproductive Science
@mhr-reprodsci.bsky.social
MHR leads the way in research focused on the foundational and translational mechanisms of mammalian reproduction. @ESHRE @eshre.bsky.social @OUPAcademic @OxfordJournals
๐ How do sperm acquire motility and the potential to fertilize? The secret lies in epididymosomes. Excited to highlight a new review in Molecular Human Reproduction by Wei et al. exploring how these nanoscale vesicles drive vital communication in the reproductive tract. ๐งต 1/2
๐ Meet MHR Associate Editor Rocรญo Martรญnez Aguilar! At @EdinburghUni, she researches heavy menstrual bleeding mechanisms to find non-hormonal treatments. ๐ฉธ๐ฌ Boost your early-career portfolio & publish with MHR! ๐ ๐ฅ Board: bit.ly/MHR_Board ๐ Submit: bit.ly/MHR_Submissions
๐ Goodbye summer holidays, hello the future of male contraception! ๐ฌ Ease back into routine with our latest Editor's Choice by Aditi Khamamkar et al. from Dr. Souvik Dey's lab (MAHE) & Broad Institute. ๐ Read this Open Access study here: lnkd.in/eUvT2pia ๐งต 1/2
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Meet MHR Associate Editor Xiaofei Sun! ๐ ๐จโ๐ฌ Research Assoc. Prof @cincychildrens.bsky.social. ๐ฌ Focus: uterine receptivity & placental development. ๐ก "MHR's strong reputation makes it an ideal platform." ๐ค Board: bit.ly/MHR_Board ๐ Submit: bit.ly/MHR_Submissi...
It's Wednesday! ๐ Time to meet the people driving MHR forward. Spotlight on Valentina Lodde, Commissioning Associate Editor & Assoc. Prof at Univ. of Milan! ๐๐ฉโ๐ซ Check out why she values our peer-review process below ๐ ๐ค Board: bit.ly/MHR_Board ๐ Submit: bit.ly/MHR_Submissions #MHR
Back to the lab? ๐ดโก๏ธ๐ฌ Itโs officially August! As many return from a July break with recharged batteries, itโs the perfect time to set new goals. And we have a major one for you... How about joining us in Stockholm? ๐ธ๐ชโ๏ธ๐
๐ฌ How do microRNAs coordinate human placental development? A new study in @MHR_Journal maps miRNAโgene co-regulation across pregnancy: ๐น 1st tri: Maternal circulating EVs lead ๐น 3rd tri: Placental tissue leads ๐น Linked to TGF-ฮฒ & birth weight ๐ academic.oup.com/molehr/advan...
The miRNA-coordinated synergism for placental gene regulation throughout pregnancy
Abstract. The regulation of gene expression by microRNAs (miRNAs) is essential during development. However, it is necessary to move beyond individual miRNA
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๐ Meet MHR Associate Editor Cameron Schmidt! ๐ ๐จโ๐ซ Asst. Prof at East Carolina Univ studying spermatogenesis. ๐ก Why publish with MHR? "Rigorous standards, efficient & transparent review." ๐ค Board: lnkd.in/ePqiktxA ๐ Submit: lnkd.in/eGXVN8da #MHR
How often do we hear that androgen signaling is required for testis formation? Spoiler alert: It isn't! ๐ A common misconception in reproductive science is equating androgen-dependent masculinization with testis development itself. ๐งต 1/4
๐ Meet MHR Associate Editor, Sandra Laurentino (Univ. of Mรผnster)! ๐ฌ She researches epigenetics & gene regulation in the human testis. Publish with us for a rigorous & fair peer review! ๐ก ๐ค Board: academic.oup.com/molehr/pages... ๐ Submit: academic.oup.com/molehr/pages... #Epigenetics
๐ฌ Join #ESHREโs Campus course and explore ICSI gamete selection, micromanipulation techniques, embryo & blastocyst biopsy, and lab troubleshooting through lectures, discussions and hands-on sessions. ๐ Lisbon, Portugal | 1โ3 Oct 26 https://www.eshre.eu/Education/Calendar-Campus-events/Precision-ART
๐ MHR Editor's Choice ๐ We're highlighting a key review on endometrial epithelium by Subramaniam, Gargett, Fitzgerald, Montgomery & McKinnon. Explore the unique biology behind cyclical regeneration and unexpected somatic mutation rates. ๐งต๐ ๐ academic.oup.com/molehr/artic...
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๐ข We are thrilled to introduce a new article type to MHR: Concise Communications! ๐โจ Have a firm conclusion that doesn't need a full manuscript? Or a provocative finding to share while completing long-term research? This short-format, peer-reviewed option is for you. ๐งต๐
๐จ New in MHR: A promising step forward in non-hormonal contraception! Justine Fischoeder, Carla Ritagliati, and team just published a new Concise Communication on assessing the efficacy of ADCY10 inhibitors in cervical mucus. ๐งฌ ๐ Read here: academic.oup.com/molehr/artic... ๐งต๐
Assessing efficacy of ADCY10 inhibitors in cervical mucus
Abstract. Male fertility depends on sperm motility, which enables sperm to traverse the female reproductive tract to the site of fertilization. Soluble ade
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Feeling Innovative? ESHRE are inviting early career scientists to submit their work for the chance to win #Molehr's coveted ECI Series Award. Find out more: oxford.ly/4kMVjqw @mhr-reprodsci.bsky.social #ESHRE2026 | #Reprosky
MHR Early Career Innovator Series
MHR is pleased to announce that, throughout 2024 and 2025, our Early Career Innovator Series has gone from strength to strength. As a result, this initiative wi
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๐ฌ Breakthrough in male infertility publishet in MHR: Researchers at Weill Cornell have created functional male gametes entirely from stem cells, bypassing the need for an animal host! They engineered a 3D calcium alginate niche to support in vitro spermatogenesis. ๐งต ๐ lnkd.in/eQntr2ME
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Happy Wednesday! ๐ Meet MHR Associate Editor, Prof. Dr. Daniela Fietz (University of Giessen)! ๐ ๐ฌ She researches the intersection of immunology & reproduction, focusing on testis biology & spermatogenesis. Get to know the board: lnkd.in/eaMkq7yH #MHR #ReproductiveBiology
Thrilled to see @Nature highlight an MHR paper by Dr. Francesca Duncan & team! ๐ฌ They challenge the traditional view of the ovary as solely a reproductive organ, uncovering an unexpected immune role. A paradigm shift for #WomensHealth! Read here: lnkd.in/ehuJXuvz
Edited embryos tell secrets of development
For the second time this month, researchers have used base editing โ a precise gene-editing technique โ to alter the DNA of human embryos. The team found that a key protein called NANOG plays a part i...
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๐ EDITOR'S CHOICE & Open Access! ๐ The human endometrium regenerates monthly, but this is linked to pathologies like endometriosis. This new review by Subramaniam et al. unpacks the somatic mutation landscape & the need for new in vitro models. ๐ Read: academic.oup.com/molehr/artic...
Somatic mutations in endometrial epithelium: biological insights and emerging in vitro models
Abstract. The human endometrium is a complex, dynamic, and poorly understood tissue involving monthly cyclical regeneration likely from adult stem/progenit
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๐๏ธ EXTRA, EXTRA! Molecular Human Reproduction (MHR) has officially reached a new Impact Factor of 4.2 in the JCR 2026! ๐โจ Huge THANKS to our authors, reviewers, ed board & readers! ๐ Check our new cover ๐ & consider MHR for your next submission!
Congratulations to Dr. Aubrey Converse and team for our latest Duncan Lab publication on the post-reproductive ovary which was selected as Editor's Choice in Molecular Human Reproduction! @mhr-reprodsci.bsky.social pubmed.ncbi.nlm.nih.gov/42271623/
The post-reproductive ovary shifts from a reproductive to an immune-like organ - PubMed
Reproductive aging in females is characterized by the irreversible depletion of ovarian follicles, yet the structure and function of the post-reproductive ovary remain poorly defined. Using paired his...
pubmed.ncbi.nlm.nih.gov
Wednesdays are for meeting the minds behind MHR! ๐ Kicking off our new series is Associate Editor Elle Roberson ๐ ๐ฉโ๐ฌ Asst. Prof at CU Anschutz studying endometrial remodeling & pregnancy success. ๐ค Board: bit.ly/MHR_Board ๐ Submit: bit.ly/MHR_Submissions #MHR #ReproductiveBiology
๐ Happy Monday! This week's #MHR Editorโs Choice dives into the future of reproductive biology. How can we better understand early human development and improve IVF/ART success rates? Enter: stem cell-based embryo models. ๐งซ๐ ๐ lnkd.in/eCgDgFGz
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Reimagining the post-reproductive landscape. โจ New data in MHR challenges the dogma that ovaries go "defunct" post-menopause. Instead, they undergo a cellular renaissance, transitioning into an active immune identity. A new paradigm for longevity. ๐ฌ pubmed.ncbi.nlm.nih.gov/42271623/
The post-reproductive ovary shifts from a reproductive to an immune-like organ - PubMed
Reproductive aging in females is characterized by the irreversible depletion of ovarian follicles, yet the structure and function of the post-reproductive ovary remain poorly defined. Using paired his...
pubmed.ncbi.nlm.nih.gov
๐ Spotlight on the Future of Reproductive Science! Following Friday's paper on placental stress, we're highlighting Rona Karahoda in our Early Career Innovator Series (ECIS)! ๐ฌ Learn about her work on the human placenta in the panel below ๐ ๐ lnkd.in/djAeTBm6 #Placenta #WomenInSTEM
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๐ฌ Friday's paper in MHR! How do high glucose ๐ฉธ, LPS ๐ฆ , & metformin ๐ impact the human placenta? A new study reveals distinct stimulus-specific signatures in placental lipid metabolism & inflammatory signaling. ๐ Read here: academic.oup.com/molehr/artic... #Placenta #ESHREjournals #WomensHealth
Metabolic, microbial, and pharmacological stimuli elicit distinct lipidomic and cytokine responses in the human placenta
Abstract. The placenta integrates metabolic and immune functions essential for fetal development, and disruptions in lipid metabolism and inflammatory sign
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๐ฃ New #OpenAccess paper in MHR! How does SARS-CoV-2 gain entry to the placenta? Pinatel, Vaillancourt & colleagues show that infection of human trophoblasts relies on a non-canonical endosomal pathway, rather than the standard ACE2/TMPRSS2 route. ๐ academic.oup.com/molehr/artic... #COVID19
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๐ Proud to name Dr. Min (Mia) Yang (UW) as our 2025 Early Career Innovator! ๐ฅ Don't miss her presenting her fascinating marmoset model research at the MHR Symposium, July 7 at #ESHRE2026. ๐ฌ ๐ Could YOU be our 2026 winner? Apply now: ๐ lnkd.in/djAeTBm6 @ESHRE #ECISaward
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๐ข New paper in #MHRJournal! ๐ฌ A study by Carine Munaut at GIGA-ULiรจge explores the S1P signaling pathway in an #adenomyosis mouse model. S1P modulation decreased tissue invasion & altered uterine immune cells, showing promise for new therapies! ๐งฌ ๐ academic.oup.com/molehr/artic...
Stage-dependent sphingosine-1-phosphate pathway modulation as a therapeutic strategy in a murine model of adenomyosis
Abstract. Adenomyosis is characterized by chronic inflammation, myometrial remodeling, and subfertility, yet therapeutic options that preserve reproductive
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