Nephrology Journal Club
@nephjc.bsky.social
A twice monthly nephrology journal club that used to meet on Twitter. Hashtag #NephJC www.nephjc.com
Check out the VA by @danyrcal Do older, sicker patients benefit from kidney transplantation? This is a nuanced "it depends" answer that is worthy of discussion. #NephSky #NephJC www.nephjc.com/news/targetva
TARGET TRIAL: The Visual Abstract — NephJC
Can a deceased donor kidney transplant offer better survival than continuing dialysis in elderly?
nephjc.com
This week we are looking at a target trial emulation on transplantation. Do older patients benefit from kidney transplant? What if the donation is after: CV death or brain death? What if the donor is a standard (SCD) or extended (ECD) criteria donor? #NephSky #NephJC www.nephjc.com/news/transpl...
Can Dialysis Outshine Transplant in the Elderly? — NephJC
This week, we will discuss whether decreased donor transplantation improves mortality in all patients. In this target trial emulation standard donor, extended donor, donation after brain death and don...
nephjc.com
12 years of #NephJC. Countless papers discussed, ideas challenged, and friendships made. 🩵No paywalls. No pharma funding, just a community that believes in free, independent nephrology education. 🌟We need your help to keep it going. Please donate www.nephjc.com/news/2026/9/...
NephJC 2026 Fall Pledge Drive — NephJC
Help keep NephJC a vital, original, and unbiased source of medical education.
nephjc.com
Can tolvaptan keep up with 3% saline? This within-subject study in healthy volunteers delivered a surprising answer - and a few eyebrow-raising physiology twist. Dive in #NephJC ✍️ by @drsaivani.bsky.social www.nephjc.com/news/tolvapt...
Raising sodium: can tolvaptan rival 3% hypertonic saline? — NephJC
Testing Tolvaptan versus 3% saline and the rate of rise of serum sodium in healthy volunteers.
nephjc.com
1/10 #NephJC #TenPosts #NephSly 🫘💊 START your steroids! A question we ask constantly but adult RCT data rarely answers after remission in steroid-sensitive MCD/FSGS, how long should the prednisolone taper actually be? 🧵 www.sciencedirect.com/science/arti...
sciencedirect.com
Steroids are useful (and have bad side effects) in patients with podocytopathies. Starting is easy, but stopping can be challenging. Are longer courses of steroids better for longer remissions? How quickly do you taper? 🐇🐢 #NephSky #NephJC www.nephjc.com/news/startsteroidtaper
Why Can’t I Quit You: Steroid Tapering in Adults with Podocytopathies (START) — NephJC
This week, we will discuss the best schedule for tapering steroids in adult patients with podocytopathies (MCD/FSGS).
nephjc.com
El Resumen Visual, gracias @dramiliflores.bsky.social #NephSky #NephJC ¿Cuánto debe durar la reducción gradual de esteroides tras la remisión de una podocitopatía? www.nephjc.com/news/startspanish
START: El Resumen Visual — NephJC
¿Podemos reducir el uso de esteroides tras la remisión?
nephjc.com
Hey #NephJC 👋 Checkout the VA by @divyaveerssneph.bsky.social This week we're looking at steroid weaning strategies in adults with podocytopathies (MCD/FSGS). 💊Steroids: easy to start🟢 but hard to stop 🛑. #NephSky www.nephjc.com/news/starttrial
START: The Visual Abstract — NephJC
Can steroid tapering be shorter after remission in adults with sensitive podocytopathy?
nephjc.com
📣Hey #NephSky We just passed 5000 #NephJC Newsletter subscribers Will you be 5001? Also, we can now be found at LinkedIN. So, if you are tired of "the bad place", but don't want to miss the latest, you can follow us there as well! www.nephjc.com/news/nephjc-on-linkedin
NephJC on LinkedIn — NephJC
NephJC is now more than twelve years old- and it’s amazing to see how far a simple idea has grown. We started with a handful of nephrologists on Twitter (yeah, we still call it that) choosing a paper ...
nephjc.com
You want a ticket to the hottest event of #KidneyWk? www.nephjc.com/news/2026/9/... Consider a donation to the fall #NephJC pledge drive
2026 NephJC Night in Denver — NephJC
On FRIDAY night, October 23rd, NephJC will host another legendary NephJC Night during ASN Kidney Week
nephjc.com
Nephrology Journal Club@nephjc.bsky.social · last mo.#NephJC runs on community magic ✨ We choose to stay free and independent and give back to our community for 12yrs 🩵 If our blogs, podcasts, or visuals have helped you, your donation keeps us going - and might get you into the coolest #KidneyWk party www.nephjc.com/news/2026/9/...
⏳ Just a bit over one month until #KidneyWk And yes... the legendary #NephJC party is happening again 🎉 🩵Join us, meet the crew, and meet people from across the world 👇Grab your ticket and come be part of the magic www.nephjc.com/news/2026/9/...
2026 NephJC Night in Denver — NephJC
On FRIDAY night, October 23rd, NephJC will host another legendary NephJC Night during ASN Kidney Week
nephjc.com
recording another episode of @freelyfiltered.bsky.social with special guests @jaykoyner.bsky.social and Rahul Ganatra of @thecurbsiders.bsky.social @kidneyboy.bsky.social @sophia-kidney.bsky.social and Vipin Varghese
One week to go until #SummerBookClub As Long as the Lemon Trees Grow by Zoulfa Katouh We will have a live chat! Tuesday 9/15/26 at 9pm EST only on Twitter #NephJC #NephSky 📚There's still time to read it and come discuss
Simmering Lemon Slices for Syrup
ALT: Simmering Lemon Slices for Syrup
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#NephJC runs on community magic ✨ We choose to stay free and independent and give back to our community for 12yrs 🩵 If our blogs, podcasts, or visuals have helped you, your donation keeps us going - and might get you into the coolest #KidneyWk party www.nephjc.com/news/2026/9/...
NephJC 2026 Fall Pledge Drive — NephJC
Help keep NephJC a vital, original, and unbiased source of medical education.
nephjc.com
1/10 #NephJC #TenPostNephJC Validation of an AI model is difficult. 🤖 Enter the REFINe trial (Reasoning Enhancement With Feedback From a Generative AI in Nephrology), a RCT of large language model (LLM) -assisted diagnostic accuracy in nephrology. www.kireports.org/article/S246...
The latest @freelyfiltered.bsky.social pod is live www.nephjc.com/freelyfilter... Prof Fervenza with @medpeedskidneys.bsky.social Nat and @kidneyboy.bsky.social Must listen for GN fans
FF96 MAJESTY, or Mentor Two — NephJC
From 2-year delay to simultaneous publication the journey from MENTOR to MAJESTY
nephjc.com
We'd like to think REFINe tested AI with clinicians, not against them, and accuracy jumped from 37% to 58%, but 1/2 of correct AI nudges were ignored #NephJC 🙌 Teamwork by @ancast13.bsky.social @assadsm.bsky.social @kiddokidney.bsky.social @danyrcal.bsky.social www.nephjc.com/news/ai-diag...
REFINe-ing AI’s Role in Nephrology Diagnosis — NephJC
This week, we will discuss the use of LLMs for the diagnosis of complex nephrology cases. Can AI help nephrologists nail the correct diagnosis?
nephjc.com
El resumen visual de REFINe (acerca de inteligencia artificial) 🤖🦾 @dramiliflores.bsky.social #NephTwitter #NephJC www.nephjc.com/news/refine-el-resumen-visual
REFINE: El Resumen Visual — NephJC
¿Puede la IA mejorar la toma de decisiones clínicas en nefrología?
nephjc.com
🤖AI is everywhere 🤖 You will be assimilated! Can the current LLMs help nephrologist diagnose complex nephrology cases? Right out of Sci-Fi movie, it is the REFINe study. VA by @kiddokidney.bsky.social #NephSky #NephJC www.nephjc.com/news/refine-the-visual-abstract
REFINe: The Visual Abstract — NephJC
Can AI boost clinical decision-making in nephrology?
nephjc.com
Early pressors in ARISE FLUIDS didn't quite arise to the occasion, except for slashing pulmonary edema ✍️ #NephJC short by @dramiliflores.bsky.social www.nephjc.com/news/2026/8/...
ARISE FLUIDS: Early vasopressors or more fluids in early septic shock? — NephJC
Once a patient with septic shock has received the first liter, what comes next? ARISE FLUIDS reshapes the ED shock strategy before 30 mL/kg: more fluid or earlier vasopressors?
nephjc.com
🚨A New #NephJC short 🩳 The first trial in pregnancy and CKD in 30 years - ORCHARD BEET 🌳 Aiming to test feasibility of nitrate administration in pregnant women with CKD by @nephroseeker.medsky.social #NephSky www.nephjc.com/news/orchard-beet
Dietary nitrate supplementation in CKD pregnancy — NephJC
First trial in pregnancy and CKD after 30 years - aiming to test feasibility of nitrate administration in pregnant women with CKD
nephjc.com
In our Stone Era 🪨 (PUSH/NO STONE) Maybe we don't have a ➕ RCT, but that doesn't exclude usefulness at the patient level 🤷♂️. Listen to the experts on the subtleties of stone treatment, don't be a 🥤nihilist. #NephSky www.nephjc.com/freelyfiltered/2026/8/push www.nephjc.com/freelyfiltered/60/nostone
FF95 The PUSH trial. Push it real good! — NephJC
PUSH Water to prevent kidney stones…or not
nephjc.com
When our patients start HD, everything gets filtered, except the debate on beta-blocker dialyzability Read #NephJC short about the new target emulation trial, suggesting the non-dialyzables may be doing some heavy MACE-lifting ✍️By @drpallaviprasad.bsky.social nephjc.com/news/targetr...
Is this the end of the beta-blocker debate in hemodialysis? — NephJC
This week, we will discuss
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1/10 #NephJC #TenPostNephJC #NephSky Can just 4 doses of an SGLT2i prevent AKI after cardiac surgery? The MERCURI-2 trial put dapagliflozin to the test. But is the benefit a treat or a trick?🫀💊 Read the article 👇 pubmed.ncbi.nlm.nih.gov/42530910/
Dapagliflozin cuts AKI after cardiac surgery - MERCURI-2 says so. But dig into the data, and it's mostly an urine output story, not a kidney protection one ✍️ #NephJC summary by @rnflex.bsky.social and @drbarbateba.bsky.social www.nephjc.com/news/2026/8/...
Too sweet to be true? Prophylactic SGLT2 inhibitors before cardiac surgery — NephJC
MERCURI-2 reports that dapagliflozin cuts postoperative AKI after cardiac surgery, but the headline result is mostly a urine-output story, not a creatinine one. That matters: urine output after surger...
nephjc.com
Excited for SGLT2 inhibitors to prevent AKI in CV surgery patients? So were we... until we got past the title. This week we're talking about "that JAMA paper "🙃 #NephJC #NephSky Here's the VA by @ManoleaA www.nephjc.com/news/2026/8/17/mercuri-the-visual-abstract
MERCURI-2: The Visual Abstract — NephJC
Does MERCURI-2 challenge how we use SGLT2i in post-operative patients?
nephjc.com
🆕 #NephJC short by @brianrifkin.bsky.social 👏 APPLAUSE for iptacopan in IgA nephropathy- final eGFR results at 24 months 👀🔎 Read more www.nephjc.com/news/2026/sh...
NephJC Short: 24-Month Iptacopan eGFR Data in IgA Nephropathy — NephJC
Iptacopan decreases proteinuria, now we get the 24-month eGFR data in patients with IgA Nephropathy.
nephjc.com
1/10 #NephJC #TenPostNephJC 💉Bicarbonate is an ICU drug that almost everyone has an opinion on. The physiology is attractive, but evidence isn’t. 🥼SODa-BIC asks if IV bicarbonate improves outcomes in ICU pts with metabolic acidosis on vasopressors. 📄 pubmed.ncbi.nlm.nih.gov/42283370/