Ever wanted to interrogate fusion gene expression at single-cell resolution? Turns out, you can! 🧬 A fun collaboration with the Oshlack lab, spearheaded by Jovana Maksimovic, and a huge team effort! Check out our preprint 👇 @jovmaksimovic.bsky.social @aliciao.bsky.social @10xgenomics.bsky.social

Jovana Maksimovic@jovmaksimovic.bsky.social · 4w ago

Gene fusions drive ~16% of all cancers & 50-70% of childhood ALL. But standard scRNA-seq can't see them — the assays aren't built to capture fusion breakpoints. We built a way to fix that. @aliciao.bsky.social @sadras-t.bsky.social @petermaccc.bsky.social @onjcri.org.au @10xgenomics.bsky.social 🧵

Autumn. And science. 🍂

An honour to have Prof Shai Izraeli visit ONJCRI and present his wisdom on the role of JAK2 and predisposition syndromes in paediatric leukaemia!