Excited to share a major milestone from my postdoctoral research: our new preprint is now live on bioRxiv! 🧠 Read the preprint here: www.biorxiv.org/content/10.6...

Mitochondrial Metabolism and Calcium Handling in Parkinson's Disease hiPSC-derived Astrocytes

Parkinson's disease (PD) is the second most common neurodegenerative disorder worldwide, and mutations in the LRRK2 and PRKN genes are among the most common familial causes of the disease. In neurodeg...

biorxiv.org

Alicia Kowaltowski@aliciakowaltowski.bsky.social · last mo.

Check out our newest preprint, beatiful work by Giovanna Cavalcante, in collaboration with Patricia Aguiar! In it, using astrocytes generated from patient-derived iPSCs, we show that Parkinson LRRK2 and PRKN mutations disrupt mitochondrial function, morphology, and calcium homeostasis.+

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Alicia Kowaltowski@aliciakowaltowski.bsky.social · 6mo ago

Our newest paper is out online! An Open-Source Code to Analyze Mitochondrial Intracellular Distribution from Fluorescence Microscopy Images Congrats @giologia.bsky.social! portlandpress.com/bioscirep/ar...

Out now! The work by Ana Gabrielle Bispo, a former Master student under my supervision at UFPA, published at Parkinsonism & Related Disorders www.prd-journal.com/article/S135... a huge “thank you!” to all collaborators to this work!

MOLECULAR ANALYSIS OF MITOCHONDRIAL COMPLEX I IN THE RESPONSIVENESS TO LEVODOPA IN PARKINSON'S DISEASE https://www.medrxiv.org/content/10.1101/2025.11.10.25339914v1

Novel mitochondrial variants associated with Parkinson's disease reveal a high heteroplasmy-weighted polygenic risk score in Brazilians https://www.medrxiv.org/content/10.64898/2026.01.15.26344224v1

mtDNA-Network: a web tool to explore mitochondrial variant profiles in complex diseases #NeuroDegeneration 🧪🧠 https://www.biorxiv.org/content/10.64898/2026.01.15.699732v1

Check it out! 🥰

Alicia Kowaltowski@aliciakowaltowski.bsky.social · 9mo ago

Check out our first preprint of the year: An Open-Source Code To Analyze Mitochondrial Intracellular Distribution From Fluorescence Microscopy Images By super-postdoc Giovanna Cavalcante in @biorxivpreprint.bsky.social www.biorxiv.org/content/10.6...