Oral Microbiology and Immunology 4th Edition is out (ASM Press; ISBN: 978-1-683-67511-2). I wrote Chapter 9: From Bacterial Genetics to Genomics! Many thanks to the Editors for the honor of contributing! #microbiology #dentistry www.wiley.com/en-us/shop/g...

Oral Microbiology and Immunology, 4th Edition

<p><b>The updated reference integrating oral microbiology and immunology for dentistry</b> <p>The study of oral microbiology and immunology has entered a new era, shaped by transformative advances in ...

wiley.com

New publication in collaboration with the Pfeifer Lab at OHSU. We identified commercially available drugs capable of inhibiting GtfC, a critical enzyme for biofilm initiation and cohesion by the pathogen, Streptococcus mutans. #microbiology #dentistry www.nature.com/articles/s41...

Drug repurposing for glucosyltransferase inhibition for targeted oral biofilm disruption - npj Biofilms and Microbiomes

npj Biofilms and Microbiomes - Drug repurposing for glucosyltransferase inhibition for targeted oral biofilm disruption

nature.com

Big week for our lab, another publication is out! #dentistry has a strategic position in the fight against AMR, yet is under-leveraged because of shortcomings in policy and education. @antimicrobial.bsky.social @amr-twilight.bsky.social @ulfdahle.bsky.social journals.asm.org/doi/10.1128/...

mGem: Dentistry is strategically positioned yet underleveraged in the battle against antimicrobial resistance | mBio

Antimicrobial resistance (AMR) is among the most significant global health threats of the 21st century, compromising the effectiveness of antibiotics that underpin modern medicine, surgery, transplant...

journals.asm.org

New Publication! Loss of de novo monounsaturated fatty acid biosynthesis impacts membrane homeostasis and stress tolerance in S. mutans, S. pyogenes, and S. pneumoniae--important pathogens that cause disease at different body sites. #microbiology journals.asm.org/doi/10.1128/...

Monounsaturated fatty acid biosynthesis is critical for streptococcal envelope homeostasis and stress tolerance | Journal of Bacteriology

Streptococcus spp. exert profound effects on human health, with several species causing significant morbidity and mortality. Although streptococcal fatty acid biosynthesis and utilization are attracti...

journals.asm.org

OHSU published an article about my lab's research! #microbiology #dentistry #bioinformatics news.ohsu.edu/2026/05/05/o...

OHSU scientist targets bacteria with precision

Jonathon Baker, Ph.D., uses advanced sequencing to develop treatments for oral infections.

news.ohsu.edu

J. Craig Venter (1946-2026) Polarizing, but an absolute science rock star who drove some of the most significant scientific accomplishments in my lifetime. Forever grateful and proud to have had the privilege of 5 formative years learning #bioinformatics while working for @jcv.bsky.social

New preprint! Using cutting edge epigenomics, we comprehensively identified DNA methylation in the model oral pathogen Streptococcus mutans UA159 and uncovered its three distinct sources. #microbiology #dentistry www.biorxiv.org/content/10.6...

Congratulations to our NIH R25 DORS Intern, Sadie Drucker, who presented her research this week at the International Association for Dental Research conference in San Diego, and is a Finalist for the Cariology Research Group Student Research Award! Way to go Sadie! #microbiology #dentistry

Matthew Barbisan and Mingzhe Guo did a great job presenting some of their research in our lab at OHSU School of Dentistry Research Day 2026!

At the OHSU School of Dentistry AI in Research Symposium, I presented that AI is a major driver of advances in third-generation sequencing technologies (e.g., Nanopore and PacBio). Our lab is using Nanopore sequencing to study DNA and RNA modifications in oral bacteria. #microbiology #dentistry

Completely agree!

Antimicrobial resistance #AMR@antimicrobial.bsky.social · 6mo ago

It is time for the dental profession to take a more active role in national action plans against #AMR and to engage systematically in antibiotic stewardship. AMR is a shared challenge that requires dentistry to make a clear contribution to stewardship efforts. www.cidrap.umn.edu/antimicrobia...

Epigenomics and epitranscriptomics, the next revolution enabled by third-generation sequencing. Our lab used nanopore sequencing to characterize the epigenome of the model pathogen Streptococcus mutans UA159 at single-nucleotide resolution, revealing 3 types of methylation. #microbiology

Nice to see this out! Our group found the tools and suggestions provided here super helpful!

Nature Biotechnology@natbiotech.nature.com · 8mo ago

Troubleshooting common errors in assemblies of long-read metagenomes - @merenbey.bsky.social @banfieldlab.bsky.social go.nature.com/44P7nSm

New publication! In this intra-departmental collaboration, we report phenotypic and genotypic differences between species of oral Corynebacteria. #microbiology #dentistry journals.asm.org/doi/10.1128/...

Comparative characterization reveals conserved and divergent ecological traits of oral corynebacteria | Microbiology Spectrum

Oral corynebacteria contribute to the structural and ecological stability of supragingival communities. Yet, their species-level functions remain poorly defined. By isolating and characterizing new st...

journals.asm.org

Very pleased to share that our recent article with @veeninglab.com in @natcomms.nature.com was selected for the Editor's Highlights, which aims to showcase the 50 best papers recently published in the area of #microbiology & infectious diseases! www.nature.com/collections/...

Microbiology and infectious diseases

This page highlights recent articles on all aspects of bacteriology, mycology, parasitology and virology, covering the biology of pathogens, host-pathogen ...

nature.com

Great opportunity in a fantastic lab!

Jeff McLean@jeffmclean.bsky.social · 9mo ago

A Postdoctoral opportunity in the McLean Lab, funded by an NIH T90 training grant, is available. This is a competitive opportunity (US citizens/perm residents). Applications due Jan 31st- must begin their fellowship no later than May 31, 2026. see dental.washington.edu/research/tra...

Really cool paper from @vincentdebakker.bsky.social @jonbakerlab.bsky.social now published @natcomms.nature.com #MicroSky www.nature.com/articles/s41...

Multi-omics profiling reveals atypical sugar utilization and a key membrane composition regulator in Streptococcus pneumoniae - Nature Communications

The pathogen Streptococcus pneumoniae can adapt to diverse microenvironments in the human body. Here, De Bakker et al. study these adaptation responses, showing unusual sugar utilization and identifyi...

nature.com

New Publication! In this collaboration with @veeninglab.com at the @unil.bsky.social, we used multi-omics to examine the response of Streptococcus pneumoniae to infection-mimicking growth conditions, discovering a novel regulator of membrane fatty acid composition. www.nature.com/articles/s41...

Multi-omics profiling reveals atypical sugar utilization and a key membrane composition regulator in Streptococcus pneumoniae - Nature Communications

The pathogen Streptococcus pneumoniae can adapt to diverse microenvironments in the human body. Here, De Bakker et al. study these adaptation responses, showing unusual sugar utilization and identifyi...

nature.com

Last week, Molly Burnside from our lab did an amazing job presenting her research on Corynebacterium at the 2025 @asm.org Conference on Biofilms. Molly is applying to PhD programs this fall, and she is going to have a huge amount of success wherever she decides to go! #microbiology #dentistry

OHSU was very well represented at the 2025 ASM #Biofilms Conference! #microbiology #dentistry

With my colleague Dr. Jens Kreth representing OHSU and the USA at what was a fantastic conference! #microbiology #dentistry #immunology

After spending 7 months earlier this year visiting our lab at @ohsunews.bsky.social on a scholarship, Dr. Felipe Farias da Silva recently presented his work with us at the 2025 meeting of the Brazilian Society of Dental Research. Way to go Felipe! #microbiology #dentistry

This summer, we hosted Sadie Drucker (Scripps Coll.) and Michelle Lee (Oregon State Univ.), through our NIH-funded DORS program. They did an amazing job, and Sadie won Best Poster at the OHSU Summer Internship Symposium! We wish them the best on the next step in their careers!

Microbiology faculty welcoming incoming OHSU President, Dr. Shereef Elnahal, at a celebration for the Knight family’s $2B donation to our university to fight cancer. #microbiology

The Baker Lab at OHSU, Summer 2025. 🦠🔬🧫🧪 #microbiology

New publication! We examined the viruses present in the human oral microbiome of children with severe cavities versus healthy teeth and there was a significant difference in the diversity of viruses present in the groups! journals.asm.org/eprint/FDPZ4...

The salivary virome during childhood dental caries | mSphere

Dental caries is the most common chronic infectious disease worldwide and is caused by dysbiosis of the oral microbiome featuring an increased abundance of acid-tolerant, acid-producing, and biofilm-f...

journals.asm.org

If high quality treatment is provided to everyone with bacterial infections + innovative new antibiotics funded ... By 2050: Health costs ⬇️ $97 billion The economy ⬆️ $960 billion Generated health benefits 🟰 $680 billion to countries Return on Investment 🟰 28 to 1 www.cgdev.org/publication/...

Excited to see this out! We identified a novel regulator of fatty acid composition in S. pneumoniae (among a lot of other cool stuff in the paper)!

Jan-Willem Veening@veeninglab.com · last yr.

Some positive news in troubled times: New preprint by Vincent de Bakker, Xue Liu @jonbakerlab.bsky.social Infection-mimicking conditions+transcriptomics/proteomics/'essentialomics'/lipidomics shows many cool things! www.biorxiv.org/content/10.1...

The Baker Lab at OHSU, Spring 2025. 🧬🔬🧫🦠 #microbiology

Congratulations to our high school intern, Daniela, and our Research Assistants, Matthew and Jonah, on publishing their pilot study on the impact of beetroot supplement on an in-vitro microbiome of e-cigarette users! #microbiology #dentistry www.tandfonline.com/doi/full/10....

The effect of Beta vulgaris on an in vitro oral microbiome of electronic cigarette users

Although touted as a safer alternative to cigarette smoking, electronic cigarette usage has been increasingly linked to a myriad of health issues and appears to impact the oral microbiome. Meanwhil...

tandfonline.com