Excited to share our new #preprint uncovering how early human forebrain is patterned. Compared to mouse, human dorsoventral and anteroposterior telencephalon patterning is strikingly delayed, which is correlated with SHH and FGF signalling differences. Read it here: www.biorxiv.org/content/10.6...
@hpscenthusiast.bsky.social
Excited to share our new publication on the mechanics of cranial neural tube closure. A really enjoyable and fruitful collaboration bridging Developmental Biology and biophysical modelling. Take a look here! www.cell.com/current-biol...
Mechanosensitive feedback organizes cell shape and motion during hindbrain neuropore morphogenesis
Pérez-Verdugo et al. show that hindbrain neuropore closure is driven by surface ectoderm actomyosin purse-string tension and active migration. These forces create reproducible patterns of cell elongat...
cell.com
Cytoplasmic lattices are a highly abundant and essential structure in mouse oocytes and embryos. Our in situ structure from early mouse embryos provides a new insight into their molecular achitecture and function. Check it out: www.biorxiv.org/content/10.6...
biorxiv.org
Excited to share our work on the structure and function of cytoplasmic lattices within mouse embryos. A collaborative effort with @niakanlab.bsky.social and work led by @kashishsingh.bsky.social and @inaharasimov.bsky.social . It is now out on BioRxiv: www.biorxiv.org/content/10.6...
It was our pleasure to have @emaniou.bsky.social at @universitypress.cambridge.org talking about her recent ongoing work as a group leader in @dublincityuni.bsky.social.
We have a new lab photo. Busy times in the Delas Lab! Last month Maria and Shaun joined us to start their PhDs. Learn more about our research and our team: delaslab.com We will be recruiting another postdoc next year so have a look through our recent work and get in touch if you are interested.
Which features of tissue flows are most robust and how do they emerge from #EpithelialMechanics? I’m @alex-plum.bsky.social (@mattiaserra.bsky.social group) and I’ll be sharing some papers on characterizing and controlling avian gastrulation flows.
PhD position available in our team @dublincityuni.bsky.social from September. Please share/ contact me for informal enquiries.
📢Our latest preprint list is now up on FocalPlane. This week’s list focusses on research using microscopy tools to answer questions in biology. As always, please let us know if there are other preprints that you’d like to see included. focalplane.biologists.com/2025/06/27/m...
Microscopy preprints - applications in biology - FocalPlane
Microscopy preprints - applications in biology - News
focalplane.biologists.com
Excited to share I’m starting my group in Dublin this September, supported by a Research Ireland Pathway award. We will work on neurulation mechanics using chicken embryos and human iPSCs. Looking forward to this new adventure! #newPI #womeninSTEM
Minister for Further and Higher Education, Research, Innovation and Science, James Lawless, has today announced €23 million in funding to support early-career researchers through the Research Ireland Pathway Programme. Read more: www.researchireland.ie/news/pathways/ #ResearchIreland
2. iPSC neuroepithelial models by @hpscenthusiast.bsky.social identifying a patient mutation in VANGL2 which diminishes apical constriction in this human model www.biorxiv.org/content/10.1...
Hello Bluesky world! 🚨New Preprint 🚨 Thrilled to share my second paper from my PhD in the @glgalea.bsky.social lab. @ucl.ac.uk doi.org/10.1101/2025...
Patient-specific iPSC models of neural tube defects identify underlying deficiencies in neuroepithelial cell shape regulation and differentiation
Spina bifida and anencephaly are neural tube defects caused by failure of embryonic neural tube closure. Successful closure requires elongation and apical constriction of neuroepithelial cells. These ...
doi.org