After a busy week in Nagoya at the Neuroendocrinology meeting, both @mathiasgua.bsky.social & @ossamaghenissa.bsky.social made the lab proud, presenting at the Japanese Neuroscience society meeting (Neuro2026) in Kobe
Mathias Guayasamin
@mathiasgua.bsky.social
PhD candidate in neurobiology and apprentice star-whisperer with the Murphy-Royal team 🚴🏽♂️ The work is mysterious and important
Lots of great feedback on some of the lab work I shared today at CANGlia. Thanks to all the organisers for putting on such a fantastic meeting!
Dr. Murphy-Royal closing out our symposium today with a great talk about early life stress and #astrocytes!!
@mathiasgua.bsky.social doing the lab proud at @canglia.bsky.social meeting in the @theneuro.bsky.social
Incredibly proud of both @mathiasgua.bsky.social and @ossamaghenissa.bsky.social who were both offered doctoral fellowships from @fondsrechercheqc.bsky.social !! 🥳🥳 It’s been a terrific year for the lads 💪(photo from past summer in France)
Incredibly proud of this paper led by @ossamaghenissa.bsky.social and @mathiasgua.bsky.social titled Basolateral 'Amygdala Astrocytes Encode Anxiety States'. www.cell.com/neuron/fullt... 🧵 below
Basolateral amygdala astrocytes encode anxiety states
Ghenissa et al. provide evidence that basolateral amygdala astrocytes reliably encode anxiety states. Using simultaneous in vivo calcium recordings across an array of behavioral tasks, combined with g...
cell.com
Nice surprise today in @thetransmitter.bsky.social daily email linking our preprint! Thank you! 😍 mailchi.mp/thetransmitt...
🚨Registration for the N American stress meeting is now open!!🚨 Really excited to be part of it and host the event in the @crchum.bsky.social in Montréal this June! www.stress2026.com/registration
Delighted to share our first preprint of the year! A project that we're all really proud of in the lab led by @ossamaghenissa.bsky.social with @mathiasgua.bsky.social in which we set out to test the role of basolateral amygdala astrocytes in anxiety behaviour. www.biorxiv.org/content/10.6...
Astrocytic Encoding of Threat in the Basolateral Amygdala
The basolateral amygdala (BLA) has long been implicated in threat detection and the generation of anxiety states. While previous experiments have demonstrated the important role of BLA principal neuro...
biorxiv.org
Starting 2026 with a thread a very recent manuscripts at Ryan Lab @tcddublin.bsky.social @tbsi-tcd.bsky.social "Extinction and subsequent updating of innate fear responses to a visual looming stimulus rely on hippocampus-dependent mechanisms" journals.plos.org/plosbiology/... @PLOSBiology
Extinction and subsequent updating of innate fear responses to a visual looming stimulus rely on hippocampus-dependent mechanisms
How does the brain balance innate responses with adaptive learning when reacting to threats? This study shows that repeated exposure to looming stimuli reduces innate defensive responses via hippocamp...
journals.plos.org
Fantastic presentation from @mathiasgua.bsky.social at @umontreal.ca Neuro department research day. Showing all his cool new data!
Fish keratocytes isolated from a fish scale crawling around. Technique: DIC microscopy. #CellBiology. Another #NikonSmallWorldReject
"Reproducibility isn’t glamorous, but it’s essential." @annechurchland.bsky.social speaks candidly in @thetransmitter.bsky.social about the obstacles to reproducibility and shares practical advice for other neuroscience labs. 🧠📈 www.thetransmitter.org/reproducibil...
Reproducibility is a team sport
Building reproducible systems across labs is possible, even in large-scale neuroscience—with rigor and collaboration.
thetransmitter.org
Thrilled to have received my first ever poster prize last week at EBBS2025 in Bordeaux 🏄♂️! Cherry on top was that I actually did my master’s in Bordeaux a few years ago and saw many friendly faces during that (VERY) hot week.
We also want to celebrate the winners of the Poster Prizes! It’s never too late to recognize great science and the hard work behind it. Well done! 👏🧠
Part 2 of France trip done. Fantastic @ebbsociety.bsky.social meeting with PhD students from the lab! Topping it off with a presentation prize for @mathiasgua.bsky.social !! 🥳
#fluorescencefriday picture I took a few months ago with our 2P of pyramidal neurons in the lateral amygdala expressing a lactate sensor 👽 title: Paths of fear
Does publishing serve science or is science serving publishing? Damian Pattinson and I (@elife.bsky.social) argue scientific publishing has evolved into a system that, rather than facilitate scholarly communication, distorts and dictates it. onlinelibrary.wiley.com/doi/10.1002/... #OpenScience
Thought this would be a nice way to enter the bsky community👇Delighted for Katie (now in Chris Dulla's lab at Tufts). Thank you to our collaborators, to the reviewers and to Cagla Eroglu for the highlight! www.science.org/doi/10.1126/...
Norepinephrine signals through astrocytes to modulate synapses
Locus ceruleus (LC)–derived norepinephrine (NE) drives network and behavioral adaptations to environmental saliencies by reconfiguring circuit functional connectivity, but the underlying synapse-level...
science.org
This is a new image from #JWST. The bright points with spikes are stars in the Milky Way. Everything else is a galaxy. Everything. Else. Is. A. Galaxy.
Great seminar from @lewisholt.bsky.social today at the @crchum.bsky.social ! Part of the ‘exit seminar’ as he closes in on the finish line of his PhD 🥲
Happy to share the commentary "Astrocytic CREB: The Hidden Driver of Stress Susceptibility" @mathiasgua.bsky.social and I put together for Biological Psychiatry www.sciencedirect.com/science/arti...
Astrocytic CREB: The Hidden Driver of Stress Susceptibility
sciencedirect.com
Program for the "Neural Circuits and Behaviour" CAN 2025 satellite is now available! We have a great day planned, and are especially looking for trainees to join the event - we'll select four trainees for talks, with a prize for best trainee talk. Details: www.eventbrite.ca/e/neural-cir...
#FluorescenceFriday Title: Solar Flare Lateral amygdala astrocyte going about its daily routine
SUPER happy that the newest version of our preprint is finally sailing the seas on biorxiv 🤩 Quite a journey where we explored the impact of early-life-stress on fear memory specificity, neuronal circuits in the lateral amygdala and the astrocytes that regulate them 🌟
Delighted to share an update to our preprint, reviewed at @elife.bsky.social, and now sent back for re-review. Colossal work by the team and driven home by @mathiasgua.bsky.social Quick 🧵 of what's new - www.biorxiv.org/content/10.1...
iBiology is a REMARKABLE and under-utilized resource for learning from some of the pioneers of microscopy--these videos are suitable for undergraduate classes or experts 🧪
🔬 Are you eager to dive into the world of light microscopy & learn from top-notch microscopists about its essential techniques for life science applications? If that sounds exciting, don’t miss out on this free, in-depth iBiology series! 👉 www.ibiology.org/online-biolo...
#FluorescenceFriday 2-photon calcium imaging recording from a magestic astrocyte. Title: twinkle twinkle little star