Such a rewarding project with @gabeloewinger.bsky.social and the team! Participant blinding is a SUPER old idea: as late as 1784!! Yet (un)blinding seems (to me) still poorly understood, e.g., compared to confounding, selection bias. I hope our work clarifies some issues, esp. in mental health RCTs
Our team of statisticians and psychedelic researchers (@awlevis.bsky.social, Mats Stensrud + Sandeep Nayak & David Yaden of @jhpsychedelics.bsky.social) developed a causal inference framework for functional unmasking in psychedelic RCTs. See our pre-print + analysis guide/code: tinyurl.com/yhwez25p