Chaitanya Chintaluri
@chaichinta.bsky.social
Food, neurotheory, and everything in between.
A mitochondrion spans dozens of spines. When one spine undergoes plasticity, only the ~2 µm mito. region beside it remodels; the rest of the organelle remains unchanged. Not one uniform power supply, but a mosaic 🧠⚡ www.biorxiv.org/content/10.1... at Max Planck Florida (@mpfneuro.bsky.social)
Good fucking God, don't give any of these things unpublished data. Its data security 101.
Carl Zimmer@carlzimmer.com · 2w agoFour days ago, a scientist was surprised by the news that Anthropic discovered new virus genes for making DNA. He says he’s been studying them for years—and feeding his data to Anthropic’s AI as part of his own research. Coincidence? Here’s my story. nyti.ms/3VSWayc
Nicolas Copernicus set our world in motion. Now, Nicoleta Condruz sets YOU-a neural circuit- in motion. In a string of pearl-like math tricks, she constructs random matrices that give her the controls to make you move, stop, dance, or repeat forever. WHAT A DEBUT! My new favorite scientist!
bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 3w agoDale's law, stability and nonlinearity are sufficient constraints to ignite transient and self-sustained neural dynamics https://www.biorxiv.org/content/10.64898/2026.09.14.751508v1
"All corners of academia will soon be flooded with AI-generated research....Maths and CS go first because their entire output is symbol manipulation...Biology comes later not because biologists are cleverer but because the rate-limiting step is physical" giorgio.gilest.ro/the-weimar-o...
The Weimar of knowledge – la bottega
giorgio.gilest.ro
So (if I understand this correctly), the way AI (companies) will "solve" all the major problems in maths, biology, and medicine in the next 5 years will be by stealing and building on the ideas of researchers naive enough to think their chats with AI companies would be private.
1/ Mitochondrial Na⁺ links metabolism, Ca2+ signaling and disease. We know how it gets in, how it gets out, and proteins that use it. But: we've never actually seen Na⁺ in single mitochondria in live cells. We started with an unusual observation, went down a rabbit hole & found some cool biology .
If Elon Musk, donated $4 to every star in the Milkyway galaxy, he would still be a billionaire.
"How do YOU know prayers don't work?" Larry David: "Because I'm bald."
Coriander chutney (coriander, ginger, green chili, sugar, salt and roasted chana dal/dalia) is a supreme pesto substitute. ONO.
When you connect with the 8th-century CE diss track throwing some shade on Bṛhaspati ...
![According to Brhaspati, thinking is due to the four constitutive
principles of matter, just as the power to intoxicate is due to the
ingredients in the wine. What we call a human body, or a sense
organ, or a physical object, is just a combination (samudāya; an as-
semblage) of earth, fire, air, and water; indeed, these four kinds of
matter are all there is. A person is a human body endued with think-
ing, and individual lives differ one from another as bubbles differ in
water. Recent work on the reconstruction of Br q haspati’s text allows us
to conjecture that it begins as follows:
1.1 Next then we will examine the nature of the reals.
1.2 Earth, fire, air, and water are the reals.
1.3 Their combination is called the ‘body’, ‘senses’, and ‘objects’.
1.4 Consciousness (caitanya) [is formed] out of these [elementary reals].
1.5 As the power to intoxicate [is formed] out of fermenting ingredients.
1.6 A human being (purus q a) is a body qualified by consciousness.
1.7 [Thinking is] from the body alone.
1.8 Because of its presence when there is a body.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:efplwzzow7blwi7kjetemmnn/bafkreib4gfye6g6yet645svqnompybqc2iwd6afuya5uvgcqik3n4wl7by)
'The book of the dead' has (what looks like) a TL;DR summary at the top of each page. The book itself is a cheat sheet of spells one took into the afterlife. #PapyrusMuseumVienna
"Fig. 2 shows a representative experiment"
Robert Insall@robinsall.bsky.social · 11mo agoThe science literature used to be more fun
Nature suggests you use their "Manuscript Adviser" bot to get advice before submitting I uploaded the classic Watson & Crick paper about DNA structure, and the Adviser had this to say about one of the greatest paper endings of the century:
Time for the world to install a gigawatt of solar power capacity 2004: A year 2010: ~ a month 2015: ~ a week Now: A day ourworldindata.org/data-insight... 🧪
Classical music: "Oh! I see it now!" Jazz: "yes! I know right... ... !"
"Our observations should prompt an essential re-evaluation of the literature concerning astrocyte-neuron mitochondrial transfer" www.biorxiv.org/content/10.1...
MitoTracker transfers from astrocytes to neurons independently of mitochondria
The neuroprotective transfer of mitochondria from astrocytes to neurons has been primarily investigated by labelling astrocytic mitochondria with the dye MitoTracker. Here we report that MitoTracker transfers to neurons from both astrocytes and astrocyte-conditioned media, independently of mitochondrial transfer. Our observations should prompt an essential re-evaluation of the literature concerning astrocyte-neuron mitochondrial transfer and in other systems in which contact-independent transfer has been observed using mitochondrial dyes. ### Competing Interest Statement The authors have declared no competing interest. MSD (United Kingdom), https://ror.org/004nn4n27, PRJ_20446 DEVINE MSD MRC The Francis Crick Institute, https://ror.org/04tnbqb63, CC2206
biorxiv.org
"Doubt thou the stars are fire, Doubt that the sun doth move, Doubt truth to be a liar, But never doubt I love." Love for dosa I'm sure.
