Proud to be part of this amazing lab which maintains a truly optimal ratio of research papers to Colin the Caterpillars! 🐛🍰🍩

Prof. Rebecca Lawson@beckyneuro.bsky.social · 10mo ago

I've been pretty absent from social media for a while, mostly for my own sanity. But my lab have had a run of amazing outputs lately, and it feels like the right moment to shake off the cobwebs and share what they've all been up to. I'm genuinely so proud of this team. Separate posts to follow!

This one was featured in the @natcomms.nature.com editors highlights page - a lovely recognition of the quality and importance of this work. Well done team!

Then we have a new paper led by Nazia Jassim @naziajassim.bsky.social on the neurochemical markers of uncertainty processing and links to trait anxiety: www.nature.com/articles/s41... @natcomms.nature.com

Computational signatures of uncertainty are reflected in motor cortex excitatory neurochemistry - Nature Communications

Using computational modelling and neurochemical analysis, this study shows how motor cortex excitatory signals guide belief updating and adaptive learning in uncertain environments.

nature.com

First up, this paper led by Bronagh McCoy: journals.plos.org/ploscompbiol... When noise and volatility are independently manipulated people behave differently depending on their anxious traits.

The relationship between anxious traits and learning about changes in stochasticity and volatility

Author summary Adapting to changes in our environment is a daily endeavour. To do so, humans and animals alike make use of feedback to guide future actions. Uncertainty in the environment can arise fr...

journals.plos.org

This work is now out in Nature Communications! 🎉 Computational signatures of uncertainty are reflected in motor cortex excitatory neurochemistry: www.nature.com/articles/s41467-025-64702-6 Huge thanks to our amazing team! @beckyneuro.bsky.social @campsydept.bsky.social @camneuro.bsky.social

Computational signatures of uncertainty are reflected in motor cortex excitatory neurochemistry - Nature Communications

Using computational modelling and neurochemical analysis, this study shows how motor cortex excitatory signals guide belief updating and adaptive learning in uncertain environments.

nature.com

Nazia Jassim@naziajassim.bsky.social · 2y ago

New preprint alert! How do we process uncertainty, and how do neurometabolites shape this?🧠Here we combine computational modeling + 7T MRS to answer these questions: www.biorxiv.org/content/10.1... With Peter Thestrup Waade, Chris Mathys, Frederike Petzchner, @beckyneuro.bsky.social & others! 🧵(1/4)

If you're interested in computational psychiatry, come chat with me about the neurochemical markers of uncertainty processing at poster A10 #BAP2025

Exciting guest lecture by Angela Roberts on anhedonia and anxiety #BAP2025

New preprint alert! How do we process uncertainty, and how do neurometabolites shape this?🧠Here we combine computational modeling + 7T MRS to answer these questions: www.biorxiv.org/content/10.1... With Peter Thestrup Waade, Chris Mathys, Frederike Petzchner, @beckyneuro.bsky.social & others! 🧵(1/4)

Neurochemical markers of uncertainty processing in humans

How individuals process and respond to uncertainty has important implications for cognition and mental health. Here we use computational phenotyping to examine individualised 'uncertainty fingerprints...

biorxiv.org

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