The Nottingham Consensus provides a policy roadmap to reduce dementia risk, the UK's leading cause of death. Recommendations include: 📢 Launch a targeted public health campaign to address key modifiable risk factors 💬 Adapt communication strategies to ensure relevance across diverse communities
Charles Marshall
@charlesmarshall.bsky.social
Professor of Clinical Neurology. Clinical Director for Dementia for NHS London. Interested in dementia diagnosis, treatment and health inequalities
New online! The Nottingham consensus on dementia risk reduction policy: recommendations from a modified Delphi process
The Nottingham consensus on dementia risk reduction policy: recommendations from a modified Delphi process
Nature Reviews Neurology, Published online: 16 January 2026; doi:10.1038/s41582-025-01173-9Translation of evidence about dementia risk into effective public health policy is a challenge. In this Consensus Statement, Demnitz-King and colleagues present 56 policy recommendations for dementia prevention, providing policymakers with a foundation for designing and implementing evidence-based dementia prevention strategies, prioritizing clear communication, targeted intervention and sustained research investment.
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New paper led by @denpru-qm.bsky.social brings together 40 dementia experts – including ARUK’s Policy team – to agree on key things decision makers need to do to help cut dementia risk. #denpruQM
How can policy reduce dementia risk? We convened a panel of experts to develop policy recommendations for dementia risk reduction, refining them through a modified-Delphi process. The final result is the Nottingham consensus, published today in @natrevneurol.nature.com 👇 tinyurl.com/4rsz2yy6
The panel developed 56 recommendations across four domains: 📢 Public health messaging 👟 Individual-level interventions 🌍 Population-level interventions 📚 Research commissioning Read our policy brief for a summary: tinyurl.com/5e2tn4u4 @charlesmarshall.bsky.social @hdemnitzking.bsky.social
Policy Briefing: The Nottingham consensus on dementia risk reduction policy: recommendations from a modified-Delphi process
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How can policy reduce dementia risk? We convened a panel of experts to develop policy recommendations for dementia risk reduction, refining them through a modified-Delphi process. The final result is the Nottingham consensus, published today in @natrevneurol.nature.com 👇 tinyurl.com/4rsz2yy6
What should the Department of Health and Social Care be doing to improve the nation’s brain health? @hdemnitzking.bsky.social and I brought UK experts together to produce a consensus roadmap for dementia risk reduction on behalf of @denpru-qm.bsky.social www.nature.com/articles/s41...
The Nottingham consensus on dementia risk reduction policy: recommendations from a modified Delphi process - Nature Reviews Neurology
Translation of evidence about dementia risk into effective public health policy is a challenge. In this Consensus Statement, Demnitz-King and colleagues present 56 policy recommendations for dementia ...
nature.com
Thank you @alzheimersresearchuk.org London Network Centre for inviting us to speak at your PPI event today. We joined lived experience experts, researchers and clinicians to discuss putting people at the centre of dementia research and care. @claudiacooper.bsky.social @charlesmarshall.bsky.social
Thrilled to share our review on imaging and fluid biomarkers in dementia with Lewy bodies with @angelikaza.bsky.social and wonderful collaborators Brit Mollenhauer Louis CS Tan Michael Bartl and Nick Fox @uclqsion.bsky.social www.sciencedirect.com/science/arti...
Diagnostic and other biomarkers of dementia with Lewy bodies: from research to clinical settings
Dementia with Lewy bodies is characterised clinically by visual hallucinations, fluctuating cognitive function, parkinsonism, and rapid eye movement s…
sciencedirect.com
✨ SHINY NEW PAPER ✨ Hearing loss is more strongly associated with tau burden than β-amyloid (Aβ) burden. @charlesmarshall.bsky.social www.sciencedirect.com/science/article/pii/S0197458025001162
Evaluating the link between hearing loss and Alzheimer’s disease neuropathology: A systematic review and meta-analysis
Hearing loss has been linked with cognitive decline and increased dementia risk. The neurobiological mechanisms underlying this relationship are not c…
sciencedirect.com
Great to see researcher Golnaz Atefi present 'Attitudes Toward Brain Health and Dementia Risk Reduction Among Minoritised Ethnic Communities in the UK' at #35AEC. Project led by Prof Naaheed Mukadam #denpruQM @claudiacooper.bsky.social @charlesmarshall.bsky.social @qmulpsychiatry.bsky.social
TWO @nihr.bsky.social Academic Clinical Fellowship opportunities are currently available to come and work with us @preventiveneur1.bsky.social Get in touch to discuss, and if you need any persuasion, here’s what our team say about what it’s like to work here! www.oriel.nhs.uk/Web/PermaLin...
🚨 New pre-print! 🚨 Dr. Avi Chandra and Ben Jacobs study dementia genetics in underrepresented populations. 🧬✨ In 51,000+ British South Asians, they show APOE influences dementia risk, underscoring the need for equitable care. Read more: www.medrxiv.org/content/10.1...
The contribution of Apoliproprotein E genetic variation to dementia risk in British South Asians
INTRODUCTION Understanding the genetic basis of dementia in diverse populations is essential to ensure that efforts to predict, prevent, and treat dementia are equitable. The strongest genetic risk fa...
medrxiv.org
🎉 Recruitment for DIADEM is closed! The DIADEM study is exploring if central hearing tests can help detect dementia. Over 450 participants across 17 UK sites—huge thanks to all involved! 💙 Shoutout to DIADEM top recruiters Lauren Bishop & Dicky Lim, who’ve seen over 100 participants together! 🏆🎂
A lot of early interest in #denpruQM consensus on dementia risk reduction policy at #AAIC25 presented by our great post-doc @hdemnitzking.bsky.social with the project led by @charlesmarshall.bsky.social Paper available later this year. @qmulpsychiatry.bsky.social @claudiacooper.bsky.social
What does the public think about preventing dementia, MS & Parkinson’s? @denpru-qm.bsky.social has just released findings from our YouGov poll, surveying 1,700 people in England, to explore attitudes to neurological prevention: bit.ly/3TwiN7l
🧠👂 Dr Avi Chandra’s latest research links hearing loss—especially central— to Alzheimer’s pathology including increased Aβ and tau burden. ❓ But what is the underpinning relationship between these factors? Watch this space!🧬🧩 To read more ⬇️ www.sciencedirect.com/science/arti...
Evaluating the link between hearing loss and Alzheimer’s disease neuropathology: A systematic review and meta-analysis
Hearing loss has been linked with cognitive decline and increased dementia risk. The neurobiological mechanisms underlying this relationship are not c…
sciencedirect.com
Great to be at the @spindnetworkplus.bsky.social Science Festival 2025 today 🎪 @hdemnitzking.bsky.social (Early Career Researcher at #denpruQM) and Patient and Public Engagement Group member Debs Smith presented findings from our consensus workshop on public health policy for dementia prevention.
Fabulous work by Phazha Bothongo! 2 years and several near mental breakdowns for us both in the making! 🧠 Causes and consequences of vascular dementia across the life course: Evidence from a UK Biobank phenome-wide and Mendelian randomization study 🧠 www.medrxiv.org/content/10.1...
Causes and consequences of vascular dementia across the life course: Evidence from a UK Biobank phenome-wide and Mendelian randomization study
Background Vascular dementia (VaD) is the second most common cause of dementia, yet its risk factors and biological mechanisms remain poorly understood. Objective To identify causes and consequences ...
medrxiv.org
Listen here➡️ Curious how divorce and widowhood affect the brain? 🧠 Take a deep dive into how these major life events may be linked to cognitive decline with Dr. Avi Chandra in the latest episode of ISTAART Voices. 🎙️ Listen now: alz.org/ISTAARTpodcast
Podcasts - ISTAART Community
alz.org
Curious about how divorce and widowhood can impact the brain? Take a deep dive into how these stressful life events can be linked to cognitive decline with Dr. Avinash Chandra in our latest episode of ISTAART Voices! 🎙️http://alz.org/ISTAARTpodcast
💼 We're looking for a mixed methods Research Assistant to join our team from August. 📈 You'll work across a range of projects utilising quantitative & qualitative methods, which may include health economics. ⏰ Apply via our website by Tuesday 6th May: shorturl.at/NxSqe Please share widely!
Quick Check Needed
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Join NIHR DeNPRU-QM at Queen Mary as a Research Assistant to support dementia & neurodegeneration policy research. 18-month role, apply by 6th May @denpru-qm.bsky.social www.dementiaresearcher.nihr.ac.uk/job/research...
Research Assistant: Equitable health and social care
Join NIHR DeNPRU-QM at Queen Mary as a Research Assistant to support dementia & neurodegeneration policy research. 18-month role starts after 6 Aug 2025.
dementiaresearcher.nihr.ac.uk
Come and work with us! Excellent research and policy research experience in a supportive socially active team
📣 We're recruiting a mixed methods Postdoctoral Research Associate to join our team from August 2025 📣 You'll have a PhD (or near completion) & enjoy working with large data sets. Apply here: shorturl.at/Z4SHk @claudiacooper.bsky.social @qmulpsychiatry.bsky.social @dementiaresearcher.bsky.social
📣 We're recruiting a mixed methods Postdoctoral Research Associate to join our team from August 2025 📣 You'll have a PhD (or near completion) & enjoy working with large data sets. Apply here: shorturl.at/Z4SHk @claudiacooper.bsky.social @qmulpsychiatry.bsky.social @dementiaresearcher.bsky.social
Postdoctoral Research Associate - QMUL Jobs
ID: 5343. Title: Postdoctoral Research Associate. Application Deadline:
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Please do think of joining us or pass this on to someone you know who might fancy it. I am, of course, rather biased but I think we are a lovely bunch, trying to help answer some really important questions. Always happy to chat to anyone who is interested!
🔈JOB OPPORTUNITY: Applications are now open for a Clinical Trials Data Manager to join the Pragmatic Clinical Trials Unit (PCTU). This is a fantastic role for someone to support a growing portfolio of clinical trials. 🔗 >> www.jobs.ac.uk/job/DMQ701/c...
Excited to share a new PhD studentship, using fMRI and MEG to detect early changes in Alzheimer's disease, fully funded for a UK student by @alzheimersresearchuk.org . Situated at UCL in Queen Square, London. Join us! tinyurl.com/nvmgroupphd
Detecting early neurovascular dysfunction in Alzheimer’s Disease and Cerebral Amyloid Angiopathy (CAA) at University College London on FindAPhD.com
PhD Project - Detecting early neurovascular dysfunction in Alzheimer’s Disease and Cerebral Amyloid Angiopathy (CAA) at University College London, listed on FindAPhD.com
findaphd.com
🚨Fantastic job opportunity for neurology trainees Neurology Clinical Lecturer post in Dementia with us @qmuldementia.bsky.social now open to applications! Please DM me for info and to discuss www.oriel.nhs.uk/Web/PermaLin...
Oriel
Published vacancies that are available for applicants to apply to. This includes key information suchs as the training programme(s), post type(s), advert information and duration.
oriel.nhs.uk
Early presentations of dementia in a diverse population alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
Early presentations of dementia in a diverse population
INTRODUCTION Improved recognition of non-cognitive presentations of dementia could reduce inequalities in dementia diagnosis, particularly if sociocultural factors influence help-seeking for cogniti...
alz-journals.onlinelibrary.wiley.com
New research, born out of community engagement work, shows that the symptoms people report prior to receiving a dementia diagnosis vary across ethnic groups. www.qmul.ac.uk/media/news/2... @qmulfmd.bsky.social @charlesmarshall.bsky.social @alzassociation.bsky.social @alzheimerssoc.bsky.social
What symptoms do people tell their GP about when they are developing dementia? Lots of non-cognitive symptoms - and in a highly diverse population we can see that it is culturally influenced. Recognising this is key to equitable diagnosis alz-journals.onlinelibrary.wiley.com/doi/full/10....
Early presentations of dementia in a diverse population
INTRODUCTION Improved recognition of non-cognitive presentations of dementia could reduce inequalities in dementia diagnosis, particularly if sociocultural factors influence help-seeking for cogniti...
alz-journals.onlinelibrary.wiley.com
Introducing Avi 🎉! He is a postdoctoral research assistant at CPN, working on the ABATED project to advance automated brain image analysis for equitable dementia diagnosis. He completed his PhD at King’s, focusing on genetics and in vivo biomarkers in MCI & AD. Watch to hear from Avi!