Another article out from the indominable @amydashwood.bsky.social! This time we review protein engineering of IL2, and the literally hundreds of muteins, antibody conjugates, fusion proteins, synthetic designs, post-translational modifications and delivery systems www.dovepress.com/articles.php...

Cytokine couture: designer IL2 molecules for the treatment of disease | ITT

Reviewing the role designer of IL2 molecules as a blueprint outlining modification pathways available to other immunotherapeutics in the treatment of disease

dovepress.com

New research article from the lab led by the amazing @amydashwood.bsky.social ! In collaboration with @vib-switch-lab.bsky.social @cbdresearch.bsky.social we engineered variants of #IL2 designed for therapeutic use. 1/11 www.sciencedirect.com/science/arti...

Directed disruption of IL2 aggregation and receptor binding sites produces designer biologics with enhanced specificity and improved production capacity

The pleotropic nature of interleukin-2 (IL2) has allowed it to be used as both a pro-inflammatory and anti-inflammatory therapeutic agent, through pro…

sciencedirect.com

It is the end of an era for the lab, with Dr Ntombizodwa Makuyana, Dr @amydashwood.bsky.social and Dr Magda Ali all successfully passing their PhD vivas over the couple of weeks! I'd like to celebrate our first @cambridgeuni.bsky.social PhD cohort by sharing their stories and their science