Excited to share our preprint led by Carlos Voogdt et al We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera. www.biorxiv.org/content/10.1...
Nazgul Sakenova
@nazgulsakenova.bsky.social
PostDoc in Bernhardt lab at Harvard | bacterial cell biology PhD @typaslab.bsky.social at EMBL | systems microbiology
How the @embo.org postdoctoral fellowship helped me in developing my academic career... happy to see my profile featured on the EMBO website! www.embo.org/people/from-...
From Fellowship to Frontline: Camille Goemans’ Mission to Tackle Antibiotic Resistance – People – EMBO
An interview with Camille Goemans, tenure-track assistant professor at the École Polytechnique Fédérale de Lausanne (EPFL) in Lausanne, Switzerland and former EMBO Postdoctoral Fellow
embo.org
I was waiting two years to see this out!! The genomic location of bacterial genes is not random!!! Congratulation on the authors (Martin Lercher and Team!). www.science.org/doi/10.1126/...
Most bacterial gene families are biased toward specific chromosomal positions
The arrangement of genes along bacterial chromosomes influences their expression through growth rate–dependent gene copy number changes during DNA replication. Although translation- and transcription-...
science.org
I attended the course in 2022, as it’s held every three years. It combines diverse, exciting science with close-knit socializing on a beautiful Greek island. Highly recommended for PhD students at any stage!
You want to learn about microbiology from a fantastic lineup of speakers on a beautiful Greek island? PhD students apply now for the @EMBO | @FEBSnews Lecture Course The New Microbiology! Registration: 1 Apr 2025 Course: 03 – 11 Sep 2025 | Spetses, Greece meetings.embo.org/event/25-new...
Resistance to one antibiotic can make bacteria resistant or sensitive to another antibiotic, opening paths for combinatorial treatments. A study in Nature Microbiology presents an approach to systematically discover and understand such antibiotic relationships. https://go.nature.com/49of3Mk 🧪
(1/3) Antibiotic resistance is costing human lives. 🦠 A study from EMBL's Typas group proposed a framework to identify antibiotic pairs that make bacteria resistant to one antibiotic but sensitive to other – this can help design new treatments and delay resistance. 🧬🧪 www.nature.com/articles/s41...
My PhD work is now published in Nature Microbiology! Please, have a look!
Excited to share our study led by @SakenovaNazgul! We used chemical genetics to identify and understand cross-resistance & collateral-sensitivity (CS) between antibiotics and reduced AMR development with CS drug pairs @embl.org with @camille_goemans @EPFL_en www.nature.com/articles/s41...
Antibiotic (abx) resistance is outpacing new abx discovery. This is worsened by cross-resistance (XR) between abx. However, resistance can also lead to collateral sensitivity (CS) to other abx, providing new treatment opportunities. In our new preprint www.biorxiv.org/content/10.1...