Admirable clarity @science.org

David Roberts@volts.wtf · 2w ago

Whew, the editors of @science.org are getting real.

We built a a self-dividing synthetic cell ! Check out this #CDlab preprint on BioRxiv: www.biorxiv.org/content/10.6... Great work by 1st author Charu Sharma who encoded dynaminA in a genome and expressed that in liposomes that then divide into daughter cells! Collaboration with Koenderink lab!

New preprint up: the power of protein language models - using a single gene (adenylate kinase) to predict the temperature optima of bacteria and bacterial communities from genomes or metagenomes www.biorxiv.org/content/10.6...

Predicting optimal growth temperatures of bacteria using learned structural information from a single protein

Temperature is a fundamental determinant of bacterial physiology and ecology. Optimal growth temperature (OGT) is highly variable across species, contributing to differences in where and when species ...

biorxiv.org

The lab is crazy about the @fifaworldclub.bsky.social ! My collaborators improved the lab for the ocasion! @unsamoficial #microbiology #FifaWorldCup

Huge Effort of @justinecollier.bsky.social Lab for understanding GcrA methylase role on cell cycle of a relevant alpha model: Agrobacterium. Papers such as this one guide us in our Bradyrhizobium research! Congrats to the team for a sound paper! www.biorxiv.org/content/10.6...

"Function-specific epistasis shapes evolutionary trajectories towards antibiotic resistance". Huge parallel experimental evolution effort in E. coli under antimicrobial pressure by @gabypetrungaro.bsky.social at Bollenbach Lab at University of Cologne. doi.org/10.1101/2025...

'Botanica No.23' by Gail Potocki

Huge work! Joint effort over four years of EPC Rocha & Fred Le Roux Labs sampling in the wild for 4 years! www.nature.com/articles/s41... @epcrocha.bsky.social @fredoleroux.bsky.social

¡Buen lunes! Hoy ⛈️ 23° de máx. La Tierra está crecientemente "fuera de equilibrio", según un reporte de la Organización Meteorológica Mundial, q preside la argentina Celeste Saulo @CelesteSau4049 👇Acabamos de vivir los 11 años más cálidos desde que se llevan registros www.nature.com/articles/d41...

The world just lived through the 11 hottest years on record — what now?

Earth is increasingly ‘out of balance’, as more heat is trapped in the atmosphere, driving global warming.

nature.com

New preprint out on bioRxiv! www.biorxiv.org/content/10.6... Can conjugative plasmids be used to control plasmid and pathogen spread? Follow me down the rabbit hole that led to this story 🧵

bsky.app/profile/alfm... And its out at Nucleic Acids Research!! Cheers!

Alf Soler-Bistué 🦠🔬🧫@alfmicrobe.bsky.social · 5mo ago

Celebrating Next paper by Larotonda et al. ! Really proud of our next work on positional Genetics of RNA polymerase. More news soon on this!!

Just published! at @narjournal.bsky.social . A new example of how gene order in bacterial genomes impacts cell physiology. Inthis episode we messed up with RNA polymerase genes! academic.oup.com/nar/article/...

Evolutionary constraints on RNA polymerase gene positioning in the genome of fast-growing bacteria

Abstract. How gene order along chromosomes affects cellular homeostasis and genome evolution remains poorly understood. Bacterial chromosomes are organized

academic.oup.com

Celebrating Next paper by Larotonda et al. ! Really proud of our next work on positional Genetics of RNA polymerase. More news soon on this!!

After 4 years of joint effort of my Lab and Dr. Llorente Team we took for first time SCRaMbLE to a bacterial system! This allowed us to massively reordered the main chromosome of Vibrio natriegens! biorxiv.org/content/10.6... Here's a 🧵

Creating bacterial genomic diversity through large-scale reconfigurations reveals phenotype robustness to organizational genome change

The ability to generate genomic diversity expands opportunities for understanding and engineering biology. Here, we demonstrate on-demand generation of diversity in bacterial genome configurations and...

biorxiv.org

Old tools for new problems: how to get glyphosate resistant/degrading bacteria using Winogradsky columns... www.sciencedirect.com/science/arti...

Materials-Based spatiotemporal analysis of microbial responses to glyphosate in Winogradsky columns

Glyphosate, the active ingredient in many broad-spectrum herbicides, is extensively used in agriculture but has come under increasing scrutiny due to …

sciencedirect.com

Thanks to the authors of this piece. I love reading about the work of inspiring pioneers in bacterial genetics. Crazy amount of discoveries! Pioneer of bacterial genetics: the legacy of Esther Miriam Lederberg academic.oup.com/genetics/adv...

Pioneer of bacterial genetics: the legacy of Esther Miriam Lederberg

Abstract. Esther Miriam Lederberg's brilliant scientific lifework, from the discovery of phage lambda, bacterial conjugation, and replica plating, provided

academic.oup.com

Super honored to have contributed to this excellent Reviews article by @val-meve.bsky.social and @amazeld.bsky.social on how extrachromosomal replicons (secondary chromosomes, chromids, megaplasmids) emerge in bacteria! 🦠 🧫 www.sciencedirect.com/science/arti...

Taming wild replicons: evolution and domestication of large extrachromosomal replicons

Bacterial genomes often contain extrachromosomal replicons (ERs), ranging from small, mobile plasmids to large, stably inherited elements, such as meg…

sciencedirect.com

Nuestros encuentros tempranos con bacterias son cruciales para el desarrollo de nuestro sistema inmunológico, muestra un estudio británico 👇 www.bbc.com/news/article...

Microbiome: First bacteria we meet can keep us out of hospital

For the first time, scientists show how our microbiome forms affects the risk of infection.

bbc.com

Great paper on replication dynamics in E. coli with more than one oriC. What would happen if we further add more oriCs?? frontiersin.org/journals/mic... Congrats Ole Skovgaad for this sound paper!!

Frontiers | An additional replication origin causes cell cycle specific DNA replication fork speed

frontiersin.org

La intervención de @VLeviLab ayer, en el Senado. También im-per-di-ble 👇 www.youtube.com/watch?v=QgTU...

VALERIA LEVY - COMISIÓN DE CIENCIA Y TECNOLOGÍA 04-06-25

YouTube video by Senado Argentina

youtube.com

Here is our newest paper recently published in Plant Communications on "Root hair growth under the control of auxin under low temperature low nutrient environment". Comments and suggestions are more than welcome! Here the pdf www.cell.com/plant-commun... Leaded by Victoria Berdion Gabarain et al.

schaechter.asmblog.org/schaechter/2... (sorry for being late with today's 𝘕𝘰𝘵𝘦𝘸𝘰𝘳𝘵𝘩𝘺. we are not "up, up and away" because of ascension day, we simply overslept 🤦‍♂️) #MicroSky

Gene Location Matters

Noteworthy — Bacterial genomes are not a laundry list of genes, but dynamic structures intimately connected with cellular function. As a result, natural selection has a heavy hand in shaping chromosom...

schaechter.asmblog.org

😍Un equipo de la UBA se ubicó entre los 5 mejores (de más de 100) en el mundial de “satélites enlatados”👇en la final del proyecto CanSat, organizado por la Universidad Nacional de México, con un satélite del tamaño de una lata que ellos mismos diseñaron y fabricaron 👇

Budget cuts do not curb our enthusiasm! Ian lab meeting today on Bradyrhizobium cell physiology! #LabMeetinDay

Estas en 3-4° año de biotecnología o carreras afines? Estamos buscando un/a estudiante de @unsamoficial.bsky.social para incorporar al laboratorio y presentar a una beca de entrenamiento de la CIC PBA! Te interesa? Vení a trabajar con nosotros!! #UNSAM #Biotecnologia !!

What a huge story!!! Integrons are page resistance genes carriers!!! Not just silent " long term memory" geneyic structures!! Congrats two all the team!!

Jose A Escudero@jaescudero.bsky.social · last yr.

🧪 Finally out after peer review, our work showing that "Mobile #Integrons carry Phage Defense Systems" is now published in Science 🎉 Short 🧵 www.science.org/doi/10.1126/...

Certainly a great place for a posdoctoral experience! Highly recommended!!!

Eduardo Rocha@epcrocha.bsky.social · last yr.

WARNING: We have a postdoc position to work on the follow-up of this work. If you're interested, the deadline is tomorrow !!! (but I'll wait a few more days for interested candidates). research.pasteur.fr/fr/job/postd...