On my way to Barcelona to attend the #Fens forum. Let me know if you are there and would like to meet. Very happy to chat about @plosbiology.org and learn about your research.

How does the human brain stop movements under realistic conditions? @janw.bsky.social and colleagues show that a fronto-basal ganglia circuit featuring the subthalamic nucleus rapidly engages and releases inhibition of specific movements, depending on the context. journals.plos.org/plosbiology/...

A cortico-subthalamic circuit rapidly engages and releases inhibition of specific movements depending on the environmental context

How does the human brain stop movements under realistic conditions? Using intracranial recordings and multi-variate EEG decoding, this study shows that a fronto-basal ganglia circuit featuring the sub...

journals.plos.org

How does the medial posterior parietal cortex contribute to temporal order memory? This study shows that population activity in macaque mPPC encodes evolving temporal context during encoding and synchronized retrieval dynamics that predict order judgments. journals.plos.org/plosbiology/...

This new study in PLOS Biology shows that when people over‑allocate rewards to themselves, this is driven by self‑interest rather than distorted performance encoding, with prefrontal and temporoparietal regions tracking performance and self‑relevance: journals.plos.org/plosbiology/...

Neuronal populations across the cortex underlie discrete, categorical, and subjective representations of visual durations

Duration perception involves multiple brain regions, but how unimodal tuning across this network supports subjective timing remains unclear. This study shows that parietal, premotor, and caudal SMA en...

journals.plos.org

Vivid dreaming makes sleep feel deeper journals.plos.org/plosbiology/...

Immersive NREM2 dreaming preserves subjective sleep depth against declining sleep pressure

Perceived sleep depth is generally thought to reflect reduced brain activity. This study shows that this relationship weakens during dreaming, suggesting that dreaming helps sustain the subjective exp...

journals.plos.org

New Unsolved Mystery, by Jörn Diedrichsen @diedrichsenjorn.bsky.social and Samuel D. McDougle @actlab.bsky.social, published this week in PLOS Biology about the contributions of the cerebellum to cognitive function: journals.plos.org/plosbiology/...

How does the cerebellum contribute to cognitive functions?

The role of the cerebellum in motor functions is well understood. But why is the same circuitry engaged in functions such as working memory, language, and social cognition? This Unsolved Mystery looks...

journals.plos.org

🧠💤 New paper out in @plosbiology.org! Together with Adriana Michalak (@dr-adri.bsky.social), Davide Marzoli, Francesco Pietrogiacomi et al., we show that dreaming, especially immersive dreaming, plays a key role in how deep sleep feels. 🔗 doi.org/10.1371/jour... @erc.europa.eu #ERC-StG #sleep

Associations between superficial white matter microstructure and diverse cortical properties revealed through a computational approach based on 3D histology and 7-Tesla MRI: journals.plos.org/plosbiology/...

Microstructural profiles of the human superficial white matter and their associations to cortical geometry and connectivity

The complex organization of the brain's superficial white matter is a challenge for studying its contribution to cortico-cortical connectivity and large-scale brain function. This study reports a nove...

journals.plos.org

journals.plos.org/plosbiology/... Transient microglial activity during postnatal development regulates infant memory persistence and retrieval.

Microglial activity during postnatal development is required for infantile amnesia in mice

Infantile amnesia limits recall of early-life memories, but its cellular basis is unclear. This study reveals that transient microglial activity during postnatal development regulates infant memory pe...

journals.plos.org

journals.plos.org/plosbiology/... Participants learned new complex tasks faster when these shared a simple task, and EEG decoding revealed associative representations of these shared tasks, linking neural association strength to behavioral generalization.

Speech comprehension relies on predictive mechanisms, but does the brain prioritize expected or unexpected information? This study shows that sharpening of sensory representations and prediction error processes co-exist at different hierarchical levels. journals.plos.org/plosbiology/...

Sensory sharpening and semantic prediction errors unify competing models of predictive processing in human speech comprehension

Speech comprehension relies on predictive mechanisms, but models disagree on whether the brain prioritizes expected or unexpected information. This study shows that sharpening of sensory representatio...

journals.plos.org

journals.plos.org/plosbiology/...

TDP-43-mediated alternative polyadenylation is associated with a reduction in VPS35 and VPS29 expression in frontotemporal dementia

Recent work has shown that TDP-43 loss in frontotemporal dementia (FTD) induces changes in alternative polyadenylation, but the functional consequences of this are unclear. This study reports that 3′U...

journals.plos.org

1/ "Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans" - out now in @plosbiology.org, led by Michele Colombo, Jacopo Favaro, & Marcello Massimini. 🧠

A liability framework for high-risk neural devices | Science www.science.org/doi/10.1126/...

A liability framework for high-risk neural devices

A no-fault compensation scheme may help balance innovation and patient protection

science.org

New paper in Imaging Neuroscience by Britta U. Westner, Tim M. Tierney, et al: Cycling on the Freeway: The perilous state of open-source neuroscience software doi.org/10.1162/imag...

we're crowd-sourcing a searchable repository of tangible benefits stemming from federally-funded research. Come enjoy the great stories; or send in an idea; or volunteer to join the team. publicusaresearchbenefits.com please share and re-share so we get more great stories in there!

The directed motion of #CerebrospinalFluid #CSF in the #brain is key for the distribution & removal of solutes, but how is this flux modulated? @bzottlab.bsky.social &co show that changes in total cerebral #blood volume drive the flow of CSF in humans @plosbiology.org 🧪 plos.io/4lOrHKm

What is the neural basis of attractive #SerialDependence? This study shows that a previous decision is reactivated during both sensory encoding and #DecisionMaking, creating a 2-stage “repulsive-followed-by-attractive” past-present interaction process @plosbiology.org 🧪 plos.io/42JCYmq

Are action potentials in vertebrate muscle essential for contraction? This study of #zebrafish lacking #SodiumChannel NaV1.4 reveals that NaVs are dispensable for #muscle contraction, so the need for muscle #ActionPotentials can vary between vertebrates @plosbiology.org 🧪 plos.io/42EXQwx

Feedback from an avatar has different effects on decision making than feedback from another human @plosbiology.org: dx.plos.org/10.1371/jour... #neurosky #neuroscience

Feedback from an avatar facilitates risk-taking by modulating the amygdala response to feedback uncertainty

How does our brain process interactions with an avatar compared to real human being? This study shows that feedback from an avatar increases risk-taking behavior in humans and is associated with lower...

dx.plos.org

Deadline extended to 28th April!! Summer School in Computational Social Cognition with fantastic keynotes by Matthew Rushworth, @dianatamir.bsky.social and @davidamodio.bsky.social. Come & learn more about computational modelling, make new friends, & explore the UK's 2nd largest city 🙂👇. Please RT!

Patricia Lockwood@thepsychologist.bsky.social · 2y ago

🌟 Join us for the 2nd Birmingham-Leiden Summer School in Computational Social Cognition! Amazing line-up of keynote speakers and instructors, new topics, and only £480 with 4 nights accommodation, social events and meals included! 🌟 www.compsoccog.com

The cerebellum is known to control limb movements; does it also control the tongue? @rezashadmehr.bsky.social &co reveal how the #cerebellum controls the #tongue in marmosets, highlighting the role of #PurkinjeCells in terminating tongue movement at the target @plosbiology.org 🧪 plos.io/4lCK9Wj

🔬 Want to improve research transparency? Join this webinar with experts from @plosbiology.org! Learn how this format enhances reproducibility & benefits science. 🎤 Dr. @npariente.bsky.social & Dr. Nikki Osborne from @rrr-research.bsky.social 📅 April 30, 3 PM CEST #OpenScience

Ten principles for reliable, efficient, and adaptable coding in psychology and cognitive neuroscience: www.nature.com/articles/s44...

Ten principles for reliable, efficient, and adaptable coding in psychology and cognitive neuroscience - Communications Psychology

Programming is essential for modern research in neuroscience and psychology, but it can quickly become a source of frustration and error. This Primer introduces ten practical principles guiding resear...

nature.com

I was pleased to this as a poster at Cosyne too!

PLOS Biology@plosbiology.org · 2y ago

How do worms navigate based on learned experience? @andrewleifer.bsky.social @jpillowtime.bsky.social &co reveal flexible behavioral strategies & distributed neural computations underlying learning-dependent odor #navigation in #Celegans @plosbiology.org 🧪 plos.io/4bYZs7c

How do worms navigate based on learned experience? @andrewleifer.bsky.social @jpillowtime.bsky.social &co reveal flexible behavioral strategies & distributed neural computations underlying learning-dependent odor #navigation in #Celegans @plosbiology.org 🧪 plos.io/4bYZs7c

"after all, scientists are problem-solvers. If the solution was easy, wouldn’t we have figured it out by now?" Check out my Editorial w/ @npariente.bsky.social discussing portable peer review, reviewer pools, AI, paying reviewers... &other solutions proposed for making peer review more sustainable🧪

PLOS Biology@plosbiology.org · 2y ago

The term "reviewer fatigue” has become familiar in scientific publishing. In this Editorial, @droutledge.bsky.social & @npariente.bsky.social discuss how we can make the peer review system more sustainable & ways that PLOS Biology is already helping to ease the burden on reviewers🧪 ▶️ plos.io/41YKIRa

Sleep regulation in #Drosophila. @sdissel.bsky.social &co show that #cholinergic #neurons in the dorsal fan-shaped body (dFB) play a major role in #sleep modulation in this neurochemically heterogeneous region of the fly brain 🧪 @plosbiology.org plos.io/42uPczp

I am pleased to report that our paper on dFB neurons is available on Plos Biology. I am extremely grateful to Dave and Brandon, my grad students, Jen, our technician/lab manager and the many undergraduate students involved in this. journals.plos.org/plosbiology/...

The dorsal fan-shaped body is a neurochemically heterogeneous sleep-regulating center in Drosophila

The role of the dorsal fan-shaped body in sleep regulation in Drosophila is contested. This study shows that cholinergic neurons in the dorsal fan-shaped body play a major role in sleep modulation in ...

journals.plos.org

Just arrived in Montreal yesterday night and look forward to attending my first #cosyne conference. Let me know if you are around and would like to chat about publishing your work in @plosbiology.org or just meet for a coffee #cosyne2025