📰 "LAMP2A gene therapy mitigates Parkinson’s disease–related pathology in nonhuman primates", published in Sciences Advances ✒️ ML Arotçarena, H Jadot, M Darricau, A Lovisotto, S Dovero, V Planche, ML Thiolat, N ,Dutheil, E Bezard, B Dehay et al. 📍 For more : www.science.org/doi/10.1126/...
LAMP2A gene therapy mitigates Parkinson’s disease–related pathology in nonhuman primates
Chaperone-mediated autophagy (CMA), regulated by its lysosomal receptor LAMP2A, is a key pathway for αSynuclein (αSyn) clearance and a direct target of αSyn-related neurotoxicity. Rodent studies show ...
science.org