📢 (1/2) Excited to share the first preprint from my PostDoc! We developed UbSeRP to map co-translational ubiquitination in a translatome-wide, revealing thousands of quality control sites, and how they reshape with aging. www.biorxiv.org/content/10.6... #proteostasis #ribosomes #preprint

Ubiquitin selective ribosome profiling reveals systematic principles of co-translational quality control

Protein biogenesis is a stress- and error-sensitive process that can lead to nascent protein misfolding and aggregation, challenging cellular proteostasis. Co-translational ubiquitination (CTU) is a c...

biorxiv.org

Super excited to share my first paper from my PhD in the @dodonova-sveta.bsky.social lab. We visualise how chromatin from archaeal cells is organised using cryo-ET and SPA. Big thanks to everyone involved in this project!

Svetlana Dodonova@dodonova-sveta.bsky.social · 2mo ago

Excited to share our new preprint! 🧬❄️ by brilliant @mdreimann.bsky.social and great collaborators! Using cryo-ET&EM, we reveal archaeal chromatin in a near-native state: variable-beads-on-a-string fibers shaped by growth phase and histone composition #ArchaeaSky www.biorxiv.org/content/10.6...

Excited to share our new preprint! 🧬❄️ by brilliant @mdreimann.bsky.social and great collaborators! Using cryo-ET&EM, we reveal archaeal chromatin in a near-native state: variable-beads-on-a-string fibers shaped by growth phase and histone composition #ArchaeaSky www.biorxiv.org/content/10.6...

Calling all archaeal enthusiasts! 🔬🔥 From molecular machines to microbial communities, Archaea never fail to surprise us! We are excited to announce the 2026 EMBO Workshop on the Molecular Biology of Archaea, 6–10 July in Cambridge, UK! Sign up here: meetings.embo.org/event/26-arc... #ArchaeaSky

Tired of knowing what you are looking for in your tomograms? Why not try bluesky-less Frosina's new self-supervised algorithm for semantic segmentation and particle picking for #teamtomo (includes a new denoiser without the need for odd/even tomos) Code is on GitHub if you want to try it out

bioRxiv Bioinfo@biorxiv-bioinfo.bsky.social · 10mo ago

CryoSiam: self-supervised representation learning for automated analysis of cryo-electron tomograms https://www.biorxiv.org/content/10.1101/2025.11.11.687379v1

We are looking for an enthusiastic postdoc to investigate cellular dormancy and ribosome hibernation across plants, fungi, and mammals using #cryoET. If you are interested, apply here: careers.exeter.ac.uk/vacancies/66....

This surprisingly relaxing footage is from SIX MILES under the ocean – and it’s the deepest ecosystem yet discovered

Check out 🧐 our new preprint 📜: www.biorxiv.org/content/10.1... Congrats🎉 to @vasilgaisin.bsky.social and Corina Hadjicharalambous, who studied contractile injection systems directly in hot spring♨️ bacterial mats🦠 #microsky #teamtomo #Chloroflexota

Our new preprint with a new #Asgard from stromatolites (and its Desulfobacterota companion). Complete circularised genomes of both, cool #cryoem images, protein modelling, etc Big group effort with a lot of people involved #archaeasky #archaea www.biorxiv.org/content/10.1...

An Asgard archaeon from a modern analog of ancient microbial mats

It has been proposed that eukaryotic cells evolved via symbiosis between sulfate-reducing bacteria and hydrogen-producing archaea. Here we describe a highly enriched culture of a novel Asgard archaeon...

biorxiv.org

Tau filaments (magenta here) tether to the membrane of extracellular vesicles in Alzheimer's disease patient brains 📷 Stephanie L. Fowler & Tiana S. Behr et al Benjamin Ryskeldi-Falcon & Karen E. Duff @ukdri.ac.uk @mrclmb.bsky.social @nature.com Neuroscience ➡️ bpod.org.uk/archive/2025...

We’ve uncovered Asgard chromatin structures formed by a Hodarchaeal histone : closed hypernucleosome conserved in archaea and an open form resembling the H3-H4 eukaryotic octasome. Fantastic work by @harshranawat.bsky.social! www.biorxiv.org/content/10.1... #Chromatin #Asgard #Archaea #cryoEM

🚨 NEW PAPER: must-read for researchers, funders & institutions 🚨 👩‍🔬 >50% of female dementia researchers experience sexism in their careers. 🏫 5x more respondents found their institution NOT helpful than helpful in addressing this. ➡️ Learn more: alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

Experiences and perceptions of sexism in dementia research careers: A global cross‐sectional survey

INTRODUCTION Sexism is prevalent in academia and is a crucial factor driving women out of the academic workforce. However, sexism in dementia research remains underexplored. This study aimed to unde.....

alz-journals.onlinelibrary.wiley.com

Apply by February 7 to join our IMPRS on Cellular Biophysics! 👉 imprs-cbp.mpg.de/call-for-app... @goetheuni.bsky.social @maxplanck.de #FluorescenceNanoscopy #STEDNanoscopy #SuperResolutionMicroscopy #MembraneBiophysics 📷 (1, 3, 4, 5, 6) Till Stephan Group, Goethe University Frankfurt

So happy to finally see this published 🎊🎊🎊🎊Thanks again to my former supervisor @brfalcon.bsky.social and my co-first @stephfowler.bsky.social & the Duff Lab Go an have a read on either the paper or how alzforum reported on this part of my PhD journey

MRC Laboratory of Molecular Biology@mrclmb.ac.uk · 2y ago

Benjamin Ryskeldi-Falcon’s @brfalcon.bsky.social group in the LMB’s Neurobiology Division, with Karen Duff's group at the UK DRI, have discovered that tau filaments are tethered to the membranes of extracellular vesicles in #Alzheimers Read more: www2.mrc-lmb.cam.ac.uk/cryo-et-reve... #LMBResearch