The Daum Lab
@daumlab.bsky.social
We investigate molecular machines and cell-surface proteins using cutting-edge cryoEM
Congratulations Will and all co-authors!
Will Stuart@willstuart.bsky.social · 2mo agoOur new paper showing two new doxycycline mechanisms against the ribosome has been accepted at Nature comms! 👌 The early access version is available here: www.nature.com/articles/s41... @daumlab.bsky.social @the-gold-lab.bsky.social @lsiexeter.bsky.social @exeter.ac.uk
We are looking for an enthusiastic postdoc to investigate molecular mechanisms of microsporidian infection using soft X-ray tomography, cryo FIB-SEM, and cryoET. If you are interested, do not hesitate to get in touch and check out the application link. The closing date: 21st June 2026.
Congratulations to Sreehari Gopinathan, winner of the Karen Davies Poster Prize at the CCPEM Spring Symposium 2026. The prize (newly established this year) honours the memory of Karen Davies, a much-valued colleague and friend in the cryoEM community, who sadly passed away in 2025.
An exciting PhD opportunity investigating ribosome hibernation in cancer is available in my lab, in collaboration with Steffen Scholpp and Ke Li! The interdisciplinary project will span cell biology, structural biology, and AI-guided modelling. Please get in touch if you are interested!
Be part of the amazing PhD community at the Living Systems Institute, UoE. @exeter.ac.uk Work in a truly interdisciplinary place with Maths, Physics, CS, Bio & Biomed co-located in one building. Applications for LSI-funded PhD studentships are open now! www.exeter.ac.uk/research/ins... #FindaPhD
We are hiring a postdoctoral researcher to investigate ribosome hibernation and activation in microsporidia using confocal microscopy, soft X-ray tomography, cryo-electron tomography, and omics approaches. If you are interested, apply here: jobs.exeter.ac.uk/hrpr_webrecr...
Last chance to apply for one of the LSI PhD projects intake Sept 2026! Deadline tomorrow, 26.11.2025, noon. www.exeter.ac.uk/research/ins... @exeter.ac.uk @lsiexeter.bsky.social
An exciting PhD opportunity is available in my lab! More info about our group and research can be found here: bdaum2.wixsite.com/daumlab Application deadline: 8th Jan 2026. Apply here: www.exeter.ac.uk/study/pg-res... If you are interested, get in touch! #ArchaeaSky #CryoEM #TeamTomo
Thank you so much Yann, Emmanuel, Oliver, Vasanthakrishnan, and Raynald for hosting me at IGDR in Rennes. It has been great to learn all about your amazing research and to enjoy your fantastic hospitality!
Another PhD opportunity in my lab starting in September 2026. The CSC-funded project aimed at Chinese nationals will explore the structure and function of the archaellum machinery. #ArchaeaSky. If you are interested, get in touch with me! www.exeter.ac.uk/research/ins...
We are looking for an enthusiastic postdoc to investigate cellular dormancy and ribosome hibernation across plants, fungi, and mammals using #cryoET. If you are interested, apply here: careers.exeter.ac.uk/vacancies/66....
Simply amazing: Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail: | Science Advances www.science.org/doi/10.1126/... @spp2330.bsky.social
Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail
This structure of an archaeal tailed virus (arTV) provides detailed insights into arTV assembly and infection mechanisms.
science.org
The Daum Lab@daumlab.bsky.social · 10mo agoWe have an exciting PhD opportunity to study ribosome hibernation in archaea using cryo-electron microscopy, tomography, microfluidics, omics, and confocal imaging. @daumlab.bsky.social, @lsiexeter.bsky.social Apply via: www.exeter.ac.uk/study/fundin... Any questions, IM me.
We have an exciting PhD opportunity to study ribosome hibernation in archaea using cryo-electron microscopy, tomography, microfluidics, omics, and confocal imaging. @daumlab.bsky.social, @lsiexeter.bsky.social Apply via: www.exeter.ac.uk/study/fundin... Any questions, IM me.
Hellooooo beautiful!😍 #CryoEM #ArchaeaSky 🧪
The Daum Lab@daumlab.bsky.social · 10mo agoOut in Science Advances: Our #cryoEM structure of HFTV1, a virus infecting the halophile #archaea. *First full atomic structure (containing all structural proteins) of any tailed virus!* Congrats and thanks to all co-authors and our fantastic collaborators! www.science.org/doi/10.1126/...
Wow, this is a thing of beauty🧪 😍😍
The Daum Lab@daumlab.bsky.social · 10mo agoOut in Science Advances: Our #cryoEM structure of HFTV1, a virus infecting the halophile #archaea. *First full atomic structure (containing all structural proteins) of any tailed virus!* Congrats and thanks to all co-authors and our fantastic collaborators! www.science.org/doi/10.1126/...
beyond cool!
The Daum Lab@daumlab.bsky.social · 10mo agoOut in Science Advances: Our #cryoEM structure of HFTV1, a virus infecting the halophile #archaea. *First full atomic structure (containing all structural proteins) of any tailed virus!* Congrats and thanks to all co-authors and our fantastic collaborators! www.science.org/doi/10.1126/...
This is incredibly beautiful, and the fact that the resolution is sufficient to follow the path of DNA spooling inside the virion head and through the tail is amazing
The Daum Lab@daumlab.bsky.social · 10mo agoOut in Science Advances: Our #cryoEM structure of HFTV1, a virus infecting the halophile #archaea. *First full atomic structure (containing all structural proteins) of any tailed virus!* Congrats and thanks to all co-authors and our fantastic collaborators! www.science.org/doi/10.1126/...
Out in Science Advances: Our #cryoEM structure of HFTV1, a virus infecting the halophile #archaea. *First full atomic structure (containing all structural proteins) of any tailed virus!* Congrats and thanks to all co-authors and our fantastic collaborators! www.science.org/doi/10.1126/...
Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail
This structure of an archaeal tailed virus (arTV) provides detailed insights into arTV assembly and infection mechanisms.
science.org
Yesterday, we celebrated the life of Deryck Mills, an amazing colleague and friend who touched so many of us and passed away far too early. A day of emotions; tears, laughter and gratitude.
Really enjoyed giving a public talk at the town hall in Eppstein, Germany, sharing our research with the local community. Many thanks to the Kulturkreis Eppstein for organising.
Check out this lovely S-layer review everyone!
Arthur Charles-Orszag@acharlesorszag.bsky.social · last yr.Archaeal S-layer proteins can adopt different symmetries that can locally accommodate areas of high curvature. The S-layer is also involved in the control of turgor and osmotic pressure, ion transport, cell-cell interactions and mating.
Are you a Biophysicist who would like to work in an interdisciplinary institute? Then do not miss this opportunity. More information on the LSI website: www.exeter.ac.uk/research/ins...
The S-layer is a crystalline protein coat found at the cell envelope of most #archaea, forming a hexagonal symmetry resulting in geometric pores. These self-assembling structures have exciting potential for #nanotechnology! The stunning images were provided by the Daum lab. #ARCTECH #microbiology
Great opportunity here, folks! Great lab, great research, great city!
Christine Moissl-Eichinger @chmoei.bsky.social · last yr.Open PhD position! Do you want to work with the human #archaeome and understand the potential effect on the #immune system? Please check the call, including another exciting opening of @cdiener.com on #microbiome research www.medunigraz.at/doktoratsstu... #microbiomesky #archaeasky #microsky
Great opportunity for all archaea lovers out there!
Daniela Barillà@danielabarilla.bsky.social · last yr.📢 New round of PhD studentships. Open to applicants worldwide. 📅 Deadline 14th March www.findaphd.com/phds/project... #microsky #archaeasky #chromosome 🧬🧬🧬 @steve-quinn-lab.bsky.social @georgerheath.bsky.social Join us in beautiful York, UK!
We are hiring! We seek a motivated postdoc to investigate the ribosomal mechanisms underpinning dormancy and awakening across eukaryotes, using cutting-edge confocal microscopy, volumeEM, and omics. @lsiexeter.bsky.social. Interested? DM me or apply via: jobs.exeter.ac.uk/hrpr_webrecr...
