Pedro J. Cabello-Yeves

@pedrojcy91.bsky.social

Microbiologist and (meta)genomicist. Picocyanobacteria are my favourite bugs. NBA, football and tennis enthusiast. Metal, progrock and electronic music variants are my medicine.

Parasitic connections: a patescibacterial epibiont, its methylotrophic gammaproteobacterial host, and their phages | mBio https://journals.asm.org/doi/10.1128/mbio.00025-26

Parasitic connections: a patescibacterial epibiont, its methylotrophic gammaproteobacterial host, and their phages | mBio

Patescibacteriota are ultra-small bacteria with reduced genomes that rely on symbiotic interactions with other prokaryotes; however, their host specificity and associated viral parasites remain poorly characterized due to limited cultured representatives. By combining targeted cultivation with genomic and microscopy analyses, we reveal previously unrecognized host lineages and expand the known viral diversity infecting this major, but still poorly known, bacterial phylum. We describe Strigamonas methylophilicida, a new patescibacterial species of the family Absconditicoccaceae that grows as an epibiont on various methylotrophic Gammaproteobacteria. This expands the host range for this family, previously found to infect only photosynthetic partners. Using enrichment cultures and metagenomics, we retrieved complete genomes of novel phages infecting S. methylophilicida and its methylotrophic hosts, including one phage that uses a modified genetic code matching that of the patescibacterium, which shows a specific viral adaptation to infect Absconditicoccaceae hosts. Our findings reveal a previously unrecognized patescibacteria-methylotrophs-phages tripartite interaction in freshwater environments, highlight the adaptations of patescibacterial phages, and shed light on the complex ecology and evolution of host-parasite-phage dynamics in understudied bacterial lineages.

journals.asm.org

👉Congress 👉One Health Pangenome 25 The microbial pangenome in one health December 2-5, 2025, Valencia, Spain www.alocongress.com/pangenome2025 👉New Deadlines Abstract Submission: Oct 31st, 2025 Early Bird Registration: Nov 14th, 2025 Students’ Fee Discount 🧬🖥️🔬🌱🧪 #bioinformatics #pangenome #science

PANGENOME2025

The biology of prokaryotic cells is directly dependent on the differential gene pools that characterize each cell or strain. This has been a fundamental aspect of epidemiology for delimiting outbreaks...

alocongress.com

Adeu SAME18, it’s been a tremendous experience. Thank you all for coming to Barcelona, bringing your awesome science to the conference and contributing to maintaining strong the SAME spirit! Looking forward to SAME19 at České Budějovice! 🙌🫶

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Planning to apply for #research #funding from the ERC? From the next application rounds, expect changes to the: • proposal structure • evaluation process • extra funding you can request • eligibility for Starting & Consolidator #Grants (from 2027) More 👇 europa.eu/!RPHWvv

Changes to the 2026 and 2027 Work Programmes

With the launch of the competitions for grants under ERC Work Programme 2026 in July of this year, several changes to the submission of applications and the evaluation of proposals will apply. The mai...

europa.eu