Mechanistic insights into phthalylsulfacetamide-induced restoration of meropenem bactericidal activity in NDM-1-positive Escherichia coli.

pubmed.ncbi.nlm.nih.gov

Next-generation bacteriophage therapeutic systems: CRISPR-based engineering, near-infrared bioimaging, and precision strategies for treating multidrug-resistant and extensively drug-resistant bacterial infections.

pubmed.ncbi.nlm.nih.gov

[Progress and application of bacteriophages in the prevention and control of zoonotic bacterial diseases].

pubmed.ncbi.nlm.nih.gov

A Triple-Modality Peptide-Antibiotic-Phage Therapy Eradicates Multidrug-Resistant Serratia marcescens Biofilms.

Combining peptides, antibiotics, and phages completely clears multidrug-resistant Serratia marcescens biofilms.

pubmed.ncbi.nlm.nih.gov

PubMed

ClearColi, an endotoxin-reduced E. coli strain, produces phages with similar yields to standard hosts, simplifying downstream purification.

pubmed.ncbi.nlm.nih.gov

PubMed

The detoxified E. coli strain ClearColi enables high-yield phage production while simplifying the critical process of removing endotoxins.

pubmed.ncbi.nlm.nih.gov

A Triple-Modality Peptide-Antibiotic-Phage Therapy Eradicates Multidrug-Resistant Serratia marcescens Biofilms.

pubmed.ncbi.nlm.nih.gov

Phage Cocktail against Acinetobacter baumannii biofilm on Endotracheal Tube: An in vitro study.

pubmed.ncbi.nlm.nih.gov

A Triple-Modality Peptide-Antibiotic-Phage Therapy Eradicates Multidrug-Resistant Serratia marcescens Biofilms.

pubmed.ncbi.nlm.nih.gov

PubMed

Using the detoxified ClearColi strain for phage production maintains yields while simplifying the critical process of removing endotoxins.

pubmed.ncbi.nlm.nih.gov

[Progress and application of bacteriophages in the prevention and control of zoonotic bacterial diseases].

pubmed.ncbi.nlm.nih.gov

Therapeutic and immunomodulatory effects of phage therapy in red hybrid tilapia challenged with Klebsiella pneumoniae.

pubmed.ncbi.nlm.nih.gov

Autophage Targeting Bile-Resistant Enterococcus sp. as a Lipid Digestibility and Emulsification Modifier and Antibiotic Alternative in Chickens.

pubmed.ncbi.nlm.nih.gov

PubMed

Using the detoxified ClearColi strain as a host simplifies phage purification by reducing endotoxins without compromising viral yield.

pubmed.ncbi.nlm.nih.gov

PubMed

Using the detoxified ClearColi strain for phage production maintains yields while simplifying the removal of dangerous endotoxins.

pubmed.ncbi.nlm.nih.gov

Quantum Dot-Phage Nanoarchitectonics for Targeted Synergistic Therapy of Methicillin-Resistant Staphylococcus aureus Wound Infections.

pubmed.ncbi.nlm.nih.gov

A Triple-Modality Peptide-Antibiotic-Phage Therapy Eradicates Multidrug-Resistant Serratia marcescens Biofilms - PubMed

Combining peptides, antibiotics, and phages completely clears multidrug-resistant Serratia marcescens biofilms.

pubmed.ncbi.nlm.nih.gov

Assessing non-porous antimicrobial surfaces against bacteria, phages and fungi: a comparative study under varied normative conditions using glass as a benchmark for microbial persistence - PubMed

The survival of pathogenic microorganisms on surfaces is contingent on environmental factors, including humidity and temperature. In order to analyze the survival and persistence in vitro, different protocols have already been implemented. This has resulted in a wide range of survival rates of all k …

pubmed.ncbi.nlm.nih.gov

[Research progress and future prospects of phage application in the treatment of mastitis in dairy cows].

pubmed.ncbi.nlm.nih.gov

[Research progress and future prospects of phage application in the treatment of mastitis in dairy cows].

pubmed.ncbi.nlm.nih.gov

[Research progress and future prospects of phage application in the treatment of mastitis in dairy cows].

pubmed.ncbi.nlm.nih.gov

Quantum Dot-Phage Nanoarchitectonics for Targeted Synergistic Therapy of Methicillin-Resistant Staphylococcus aureus Wound Infections - PubMed

Chronic wound infections caused by methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) often refractory to conventional therapies due to bacterial drug resistance and biofilm formation. To address this challenge, we developed a synergistic antibacterial nanoarchitectonics integrating bacteriop …

pubmed.ncbi.nlm.nih.gov

Mechanistic insights into phthalylsulfacetamide-induced restoration of meropenem bactericidal activity in NDM-1-positive Escherichia coli - PubMed

The emergence and global spread of New Delhi metallo-β-lactamase-1 (NDM-1) pose a severe threat to the efficacy of carbapenems, which are considered the last line of defense against infections caused by multidrug-resistant gram-negative bacteria. In this study, through virtual screening and enzyme a …

pubmed.ncbi.nlm.nih.gov

A Chirality-Converted Bacteriolytic Dodecapeptide Regulates Vibrio-Induced Polymicrobial Infection and Ameliorates Invasion-Associated Gut Microbiota Disequilibrium - PubMed

The polymicrobial infections caused by Vibrio species, especially multidrug-resistant isolates, are posing increasing threats to the health of coastal residents. Herein, a novel dodecapeptide, denoted as D-zp37, was designed and synthesized, aiming to combat these notorious pathogens. Experimental r …

pubmed.ncbi.nlm.nih.gov

Complete genome sequence of MP2445, a mycobacteriophage that can infect Mycobacterium bovis BCG and Mycobacterium fortuitum - PubMed

Mycobacteriophage MP2445 exhibits siphovirus morphology and infects <i>Mycobacterium smegmatis</i>, <i>Mycobacterium bovis</i> BCG, and <i>Mycobacterium fortuitum</i>. Its genome is 50,711 bp in length, has a GC content of 63.34%, and contains 78 protein-coding sequences and one tRNA. MP2445 shares …

pubmed.ncbi.nlm.nih.gov

Assessing non-porous antimicrobial surfaces against bacteria, phages and fungi: a comparative study under varied normative conditions using glass as a benchmark for microbial persistence - PubMed

The survival of pathogenic microorganisms on surfaces is contingent on environmental factors, including humidity and temperature. In order to analyze the survival and persistence in vitro, different protocols have already been implemented. This has resulted in a wide range of survival rates of all k …

pubmed.ncbi.nlm.nih.gov

A Triple-Modality Peptide-Antibiotic-Phage Therapy Eradicates Multidrug-Resistant Serratia marcescens Biofilms - PubMed

A triple-combo of peptides, antibiotics, and phages completely wiped out MDR Serratia marcescens biofilms.

pubmed.ncbi.nlm.nih.gov

A Triple-Modality Peptide-Antibiotic-Phage Therapy Eradicates Multidrug-Resistant Serratia marcescens Biofilms - PubMed

A triple combo of peptides, antibiotics, and phages completely wipes out MDR Serratia marcescens biofilms.

pubmed.ncbi.nlm.nih.gov

Comparison of gut viromes across captive mammals reveals extensive genetic diversity in bacteriophage dark matter and mammalian viruses - PubMed

Comprehensive characterization of mammalian gut viromes is essential for early detection of commensal and potentially zoonotic viruses and for reducing the risk of cross-species transmission. Viral metagenomics was applied to profile gut viral communities from zoo mammals maintained across multiple …

pubmed.ncbi.nlm.nih.gov

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