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Nicolas Pégard

@nicopegard.bsky.social

Associate Professor at the University of North Carolina. trying to build a school of Engineering at UNC. Engineer at heart, accidental neuroscientist, faculty by day, tech dev by night. Allergic to fake science, thoughts my own.

18 Posts157 Follower207 Folgt
Cell Biology and Physiology at UNC-CH@unc-cbp.bsky.social · 8mo ago

At 22, most students plan their next step—Ellora McTaggart built a company. Read how the UNC alum and 2 faculty developed wearable biosensing glasses that offer insights into how people respond to the world. #biotech @joserodroma.bsky.social @nicopegard.bsky.social research.unc.edu/story/eyes-o...

Eyes on the Brain - UNC Research

A Carolina alumna and her former research mentors are developing wearable smart glasses that could one day support new insights into mental health.

research.unc.edu

Piali Sengupta@senguptalab.bsky.social · 12mo ago

TT faculty job opening in #Neuroscience! We are looking for a colleague to join us in our fantastic Biology Department and Neuroscience Program at Brandeis. We are a group of *very* collaborative, supportive, and productive scientists (& humans!) so please apply academicjobsonline.org/ajo/jobs/30961

Brandeis University, Biology Department

Job #AJO30961, Assistant Professor in Biology and Neuroscience Program, Biology Department, Brandeis University, Waltham, Massachusetts, US

academicjobsonline.org

Dan Garisto@dangaristo.bsky.social · last yr.

NEW: NSF will be kicked out of their building. Announcement will be made tomorrow by HUD Sec. and Governor of VA. HUD will take over the NSF building over the next two years. NSF staffer: "There is no planning for NSF, no identified future location, appropriation for a new building or a move."

Brittany Charlton@britshmit.bsky.social · last yr.

📢BREAKING: Just left the courthouse for our NIH grant termination case Judge ruled terminations are “VOID & ILLEGAL” As a plaintiff, I felt a wave of relief & hope; he acknowledged the discrimination & harm Closed by asking, ‘Have we fallen so low? Have we no shame?’

Nicolas Pégard@nicopegard.bsky.social · last yr.

Microscopy produces images, but images are not always what we want. With collaborators at Duke and HHMI, we show that optical tricks can transfer more information from the sample to the camera, and then, algorithms retrieve publishable data. www.spiedigitallibrary.org/journals/neu...

Compressive streak microscopy for fast sampling of fluorescent reporters of neural activity

SignificanceIn vivo one-photon fluorescence imaging of calcium and voltage indicators expressed in neurons enables noninvasive recordings of neural activity with submillisecond precision. However, data acquisition speed is limited by the frame rate of cameras.AimWe developed a compressive streak fluorescence microscope to record fluorescence in individual neurons at high speeds (≥200 frames per second) exceeding the nominal frame rate of the camera by trading off spatial pixels for temporal resolution.ApproachOur microscope leverages a digital micromirror device for targeted illumination, a galvo mirror for temporal scanning, and a ridge regression algorithm for fast computational reconstruction of fluorescence traces with high temporal resolution.ResultsIn simulations, the ridge regression algorithm reconstructs traces of high temporal resolution with limited signal loss. Validation experiments with fluorescent beads and experiments in larval zebrafish demonstrate accurate reconstruction with a data compression ratio of 10 and accurate recordings of neural activity with 200- to 400-Hz sampling speeds.ConclusionsOur compressive microscopy enables new experimental capabilities to monitor activity at a sampling speed that outpaces the nominal frame rate of the camera.

spiedigitallibrary.org

Matthew Hahn@matthewhahn.com · 2y ago

I am a former incarcerated firefighter. I served in a California fire camp from 2009 to 2012. Misinformation is afire on the internet, so here are facts about the prison firefighter program, all in one place. A thread.

Nicolas Pégard@nicopegard.bsky.social · 2y ago

What incentives do you have as faculty to set high standards and not give a free A to all your students ? i just saw one of my colleagues -who is a much better teacher than me- get trashed with nonsensical claims on ratemyprofessor, in a class that I taught too, probably by students who got a B.

Nicolas Pégard@nicopegard.bsky.social · 2y ago

Looking at the last 10 emails I received from students taking my class I can see similar GPT-like phrasing across 5 of them. LPT, a short, personal email, even filled with your human typos is far more appreciated than any of the LLM diarrhea you force me to read.