Can the active enantiomer of praziquantel outperform the racemate in amorphous solid dispersions? Comparing racemic and (R)-PZQ formulations, this study highlights the role of chirality, polymer selection and crystallisation in improving drug release. 📖 Read it here: pubs.rsc.org/pm/article/2...

We are delighted to introduce our new RSC Pharmaceutics Editorial Board member, Dr Alexandros Sofias 📢 Dr Alexandros Sofias is based at the Institute for Experimental Molecular Imaging (ExMI), RWTH Aachen University Hospital. Find out more in our blog post: blogs.rsc.org/pm/2026/08/0...

Discover how RSC Pharmaceutics Advisory Board member Hitesh Kulhari and team engineered geniposide-loaded solid lipid nanoparticles for sustained release and induced apoptosis in human lung cancer cells. Read their study for free: pubs.rsc.org/pm/article/d...

Exploring chemo-immunotherapy via co-delivery of IL12 mRNA and doxorubicin loaded polymeric nanoparticles 🧬 Read the article by Asha Patel and colleagues at Imperial College London @imperialcollegeldn.bsky.social, recently published in RSC Pharmaceutics: 🔗 doi.org/10.1039/d6pm...

📢 Read the latest research from RSC Pharmaceutics Advisory board member Eliana Lima and coworkers: Lipid phase organization controls drug partitioning and release across lipid nanocarriers 🔗 doi.org/10.1039/d6pm...

Designing effective vaccines goes far beyond the antigen. 🧫 In this new article, Saman Zafar and colleagues explore the formulation challenges shaping stability, delivery, and immune response, and why smarter design is key to next‑gen vaccines. Read more 👇 pubs.rsc.org/pm/article/2...

Check out this article by Rajapaksha, Karunaratne and team focused on nanoparticles for improved oral bioavailability of folic acid and ferrous ascorbate 💊 doi.org/10.1039/D3PM...

Novel alginate nanoparticles for the simultaneous delivery of iron and folate: a potential nano-drug delivery system for anaemic patients

Biopolymer nanoparticles have emerged as promising carriers for bioactive agents, offering sustained or controlled release and improved biocompatibility. The purpose of this study was to design novel ...

doi.org

RSC Pharmaceutics has reached an important milestone – its first Journal Impact Factor of 5.5. The work focusses on emerging technologies, including drug delivery, precision medicine and enhanced drug targeting, with potential to drive real change in health. Discover our metrics ➡ buff.ly/Os2BVlM

Unlocking the potential of chitosan in drug delivery 🐚 Research from Pereira Parchen et al. reviews how tailored chemical modifications and self‑assembly strategies can create versatile nanocarriers for improved drug delivery and performance. Explore the research: pubs.rsc.org/en/content/a...

Chitosan-based nano-objects for drug delivery: a review of their chemical modifications, supramolecular organization and biological fate

Chitosan is a widely applied polysaccharide in different fields due to its versatility, biocompatibility and low toxicity. Its structure possesses reactive functional groups that can be modified witho...

pubs.rsc.org

Join us next Tuesday, 16 June, for this exciting Desktop Seminar! Featureing Jorge Almodovar (UMBC), who will discuss his group's work on "Engineering biodegradable microneedle patches to deliver pain medication for farm animals". #chemsky Register here: rsc.zoom.us/webinar/regi...

RSC Pharmaceutics would like to thank all of our reviewers for helping to preserve quality and integrity in pharmaceutics literature. We would also like to highlight the Outstanding Reviewers for RSC Pharmaceutics in 2025 🌟 Find out who they are in this Editorial: 🔗 doi.org/10.1039/D6PM...

This recent article by Myrovali and coworkers presents 3D printed pills of magnetic nanoparticles for targeted drug delivery and localised drug release 🧲 Check it out for free here: doi.org/10.1039/D4PM...

Drug-loaded 3D-printed magnetically guided pills for biomedical applications

The traditional treatment of stomach cancer is based on a combination of surgery and chemo/radiotherapy leading to severe side effects and endless pain. The objective of this study is the development ...

doi.org

Tackling antibiotic resistance with nanotechnology 🧪 This review explores how silver nanoparticles can enhance antibiotic efficacy - particularly alongside vancomycin - to tackle resistant bacterial infections. Read for free here: pubs.rsc.org/en/content/a...

Check out this recent article by Alice Parkes and co-workers: By tuning spray drying conditions, the work demonstrates improved stability in co‑amorphous drug–drug systems, offering a route to more efficient formulations 💊 Read it for free here: pubs.rsc.org/en/content/a...

We are delighted to introduce our new RSC Pharmaceutics Advisory Board member, Dr. Defang Ouyang 📢 Dr Defang Ouyang is an Associate Professor at the University of Macau. Find out more in our blog post: blogs.rsc.org/pm/2026/05/1...

RSC Pharmaceutics was delighted to sponsor four poster prizes at the 5th Annual South Florida Translational Research Symposium on the 9-10th of April 2026 at Florida International University 🏅 Find out more in our blog post: blogs.rsc.org/pm/2026/05/1...

Check out this recent article by Ben Boyd and team on the use of infant formula and nanoparticle formulations for the solubilisation and delivery of lumefantrine and artemether 🥛 Read it for free here: doi.org/10.1039/D5PM...

Reformulating lumefantrine as Flash NanoPrecipitated particles and the impact of incorporation into milk-based formulations on drug solubilisation during digestion

Lumefantrine and artemether are currently used as one of the first line therapies for treatment of uncomplicated malaria. However, commercially-available lumefantrine/artemether tablets often result i...

doi.org

Intranasal nanocarriers offer safer and more targeted delivery of valproic acid during pregnancy. Read all about it in the latest review from RSC Pharmaceutics Editorial Board member Francesca Taraballi, Bruna Corradetti and team 📖 doi.org/10.1039/D5PM...

Redesigning valproic acid therapy in pregnancy: intranasal liposomes for targeted maternal treatment

Valproic acid (VPA) is a potent antiseizure medication and mood stabilizer, yet its teratogenicity severely limits safe use during pregnancy. Despite guidelines advising against VPA use in women of re...

doi.org

Have you seen the cover images for Issue 2 of RSC Pharmaceutics? You can read the story behind the cover for free here: pubs.rsc.org/en/content/a...

Have you seen the cover images for Issue 2 of RSC Pharmaceutics? You can read the story behind the cover for free here: pubs.rsc.org/en/content/a...

Have you seen the cover images for Issue 2 of RSC Pharmaceutics? You can read the story behind the cover for free here: pubs.rsc.org/en/content/a...

Discover the advantages, challenges, and recent advances of effervescent tablets in this recent review from Natassa Pippa and coworkers 🫧 Check it out for free here: doi.org/10.1039/D4PM...

Recent advances in the technology of effervescent tablets: lessons learned and future perspectives

Effervescent tablets are solid pharmaceutical dosage forms that are widely accepted due to their advantages. The improvement in patient compliance results from a combination of factors related to both...

doi.org

Discover the potential future of personalised medicine! Read about the application of artificial intelligence to smart drug delivery in the latest review by Kumar and team 📖 Read the review for free here: doi.org/10.1039/D5PM...

Artificial intelligence in smart drug delivery systems: a step toward personalized medicine

One of the most interesting applications of artificial intelligence is in the design of drug delivery systems. Smart drug delivery systems can transfer drugs to specific tissues and cells, enhancing t...

doi.org

RSC Pharmaceutics Advisory Board member Emily Day and team demonstrate that fluorescent dye micelles can be present in dye-labelled nanoparticle solutions, giving false positive results for nanoparticle tracking. Luckily, they also explore potential separation techniques! doi.org/10.1039/D5PM...

Standard purification methods are not sufficient to remove micellular lipophilic dye from polymer nanoparticle solution

Tracking nanoparticles’ location is imperative for understanding cellular interactions, pharmacokinetics, and biodistribution. DiD is a lipophilic dye commonly used to label nanoparticles for traffick...

doi.org

Discover the application of lipid nanoparticle technology to ligand-free targeted drug delivery in this review by Hideyoshi Harashima and coworkers! Access for free here: doi.org/10.1039/D5PM...

A new strategy for the extrahepatic delivery of lipid-based nanomedicines: a protein corona-mediated selective targeting system based on an ionizable cationic lipid library

Applying lipid nanoparticle (LNP) technology to ribonucleic acid (RNA) nanomedicines was integral to the success of mRNA vaccines against COVID-19. To expand the power of LNP technology, extrahepatic ...

doi.org

Have you seen the cover images for Issue 1 of RSC Pharmaceutics? You can read the story behind the cover for free here: pubs.rsc.org/en/content/a...

Have you seen the cover images for Issue 1 of RSC Pharmaceutics? You can read the story behind the cover for free here: pubs.rsc.org/en/content/a...

Have you seen the cover images for Issue 1 of RSC Pharmaceutics? You can read the story behind the cover for free here: pubs.rsc.org/en/content/a...

Check out this review by Remo Eugster and Paola Luciani on how AI and digital tools can make pharma greener, faster, and more resilient: mapping a sustainable future for drug development 🖥️ @luciani-lab.bsky.social pubs.rsc.org/en/content/a...

Advancing sustainability through digitalization: from drug development to patient care

Digitalization is transforming the pharmaceutical industry, offering innovative solutions to enhance sustainability across the pharmaceutical value chain. From drug discovery to patient care, digital ...

pubs.rsc.org

Olivia Merkel and team report a DoE-driven screening on an automated microfluidic small-scale device which enabled identification of stable RNA/PBAE nanoparticles. Transfer of optimized process parameters to a large-scale device confirmed robust and scalable manufacturing 🧪

QbD product development: rapid optimization and scale-up of PBAE-based siRNA delivery via DoE-guided microfluidics

Poly(β-amino ester) (PBAE)-based nanoparticles have emerged as promising carriers for RNA delivery, yet clear design rules linking formulation parameters to performance are still lacking. In this…

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