A little glimpse into the ups and downs behind this work and the people behind the paper! 🔬 Special thanks to @dev-journal.bsky.social for giving us the opportunity to share the story as a Research highlight with the development and stem cell biology community and beyond.

Development@dev-journal.bsky.social · last mo.

To learn more about this work and the people behind it, we talked to Rashi Agarwal @rashi-agarwal.bsky.social, Joergen Benjaminsen and Joachim Wittbrodt @wittbrodtlab.bsky.social. journals.biologists.com/dev/article/...

Delighted to share our work on how microglia regulate stem cells during the homeostatic development of medaka. This project has been in the works for quite some years since its discovery. Do give it a read and let me know your thoughts on this! #stemcells #microglia #medaka #development

Development@dev-journal.bsky.social · last mo.

Microglia eat stem cells to keep the retina in shape This Research Highlight showcases work by Rashi Agarwal @rashi-agarwal.bsky.social, Joachim Wittbrodt @wittbrodtlab.bsky.social and colleagues. journals.biologists.com/dev/article/...

New pre-print klaxon: "Discovery and characterisation of gene by environment and epistatic genetic effects in a vertebrate model" led by the excellent Bettina Welz + @saulpierotti.bsky.social from @wittbrodtlab.bsky.social, Felix Loosli, Kiyoshi Naruse and my own lab www.biorxiv.org/content/10.1...

Discovery and characterisation of gene by environment and epistatic genetic effects in a vertebrate model

Phenotypic variation arises from the interplay between genetic and environmental factors. However, disentangling these interactions for complex traits remains challenging in observational cohorts such...

biorxiv.org

Calling all #MedakaPI researchers! Join us in Heidelberg, Germany from July 22-24, 2025 for our collaborative meeting! Register now & take advantage of early bird rates until April 15th! meetmedaka.com/registration/ 🐟 #MedakaResearch #ModelOrganisms #ScienceConference #FishModels #Heidelberg2025

Our study reveals how microglia prune retinal stem cells in medaka fish and provides novel insights into the chemokine signaling involved. If you are excited about the emerging field of immune-stem cell interactions, do check this preprint! www.biorxiv.org/content/10.1... @wittbrodtlab.bsky.social

Immune surveillance and pruning of neuronal stem cells in the medaka retina

Stem cell populations in tissues require precise regulation of their number and quality to maintain proper organ growth and regenerative capacity. Amongst various regulatory mechanisms, immune cells a...

biorxiv.org