How can we measure mutant Huntingtin #aggregates in the 🧠 brain? We investigated a novel ☢️ #PET imaging radioligand, [18F]CHDI-385 to track 📈 non-invasively the mHTT aggregates in the brain 🧠 of a mouse 🐭 model of #Huntington’s Disease. #openaccess article published in JNM: 👉 lnkd.in/eK68-UbU

New HD focused article leveraging multi-modal imaging from our long-standing collaboration with @danielebertoglio.bsky.social and colleagues! www.sciencedirect.com/science/arti...

Longitudinal investigation of structural and resting-state effective connectivity alterations in a non-human primate model of Huntington's disease

Huntington's disease (HD) is a genetic neurodegenerative disorder caused by expanded CAG repeats in the huntingtin gene which produce a mutant hunting…

sciencedirect.com

🎉 Very proud of our PhD student Marion Decrop for securing a PhD Fellowship from FWO @fwovlaanderen.bsky.social! 👏 🎉 Using pharmacological fMRI 🧲, this fellowship will allow us to understand how the dopaminergic system is functionally impacted in Huntington's disease 🧠

New pre-print from an incredibly productive collaboration between my lab and the team led by @danielebertoglio.bsky.social

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · last yr.

Longitudinal Investigation of Structural and Resting-State Effective Connectivity Alterations in a Non-Human Primate Model of Huntington's Disease https://www.biorxiv.org/content/10.1101/2025.07.18.665554v1

Great couple of inspiring days at the #WingsforLife scientific meeting in Salzburg! 🇦🇹 Really pleased to share the update of our project with the🥼community & very thankful for the #funding support on the development of in vivo imaging ☢️ 🧲 #biomakers for spinal cord injury! 🐁🔬

Running for those who can't 👟 #WingsforlifeWorldRun

Can we identify biomarkers responsive to mHTT lowering? In this new study, we investigated 💧 #CSF and ☢️ #PET biomarkers that could be used non-invasively to track 📈 the temporal response to #mHTT modulation in mice 🐭. #openaccess article: 👉 lnkd.in/eqTirauF

How can we quantify 🧠 SV2A PET imaging noninvasively in rats 🐁? In this new study led by Lori Berckmans, we investigated non-invasive quantification methods for PET imaging with [18F]SynVesT-1 ☢️ as an alternative to blood 🩸 sampling for arterial input function. link.springer.com/article/10.1...

What a fantastic #EMIM2025 in Bilbao 🇪🇸! A whole week filled with inspiring science and scientific exchange and many friends! Antwerp was undoubtedly well represented!🔬☢️🧲 Thank you #ESMI for the fabulous organization! 👏

This week we are at the 20th EMIM meeting in Bilbao 🇪🇸 with several #oral and #poster contributions! 📢 If interested, don't miss the chance to talk with the presenters! 🧲☢️🔬 #EMIM2025

Just arrived✈️ in Bilbao 🇪🇸 and already loving this ☀️ weather! Ready for #EMIM2025!

A very fruitful edition of our group's MaRBEL meeting of the 🇧🇪 Belgian 🧲 MR Research Community! - 🏆Best Scientific Poster Award for Monica van den Berg 👏 - 🏆Best Protocol Poster Award for Marion Decrop 👏 - 🗨️ Invited talk by Joëlle van Rijswijk 👏 - 🗨️ Selected talk by Claudia Schrauwen 👏

New paper out! 👏🥳 Our work by Judith Van Rooij explored how caloric restriction and resveratrol 💊supplementation affect brain 🧠 function as measured with rsfMRI 🧲 and whether these effects differ by sex in rats 🐁. www.frontiersin.org/journals/nut...

Frontiers | Short-term caloric restriction or resveratrol supplementation alters large-scale brain network connectivity in male and female rats

frontiersin.org