Our multi-omic analysis of the primate striatum reveals heterogenous MSN organization across its rostro-caudal extent, new MSN subtypes, and subtype-specific disease enrichment. www.biorxiv.org/content/10.1...
A Multimodal Atlas Reveals the Anatomical Distribution of Medium Spiny Neuron Subtypes and a Novel RGS6+ Population in the Primate Striatum
The primate striatum and its principal neuron type, the medium spiny neuron (MSN), integrate cortical and subcortical signals related to movement, cognition, and emotion. These signals are processed t...
biorxiv.org
bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 10mo agoA Multimodal Atlas Reveals the Anatomical Distribution of Medium Spiny Neuron Subtypes and a Novel RGS6+ Population in the Primate Striatum https://www.biorxiv.org/content/10.1101/2025.11.16.688724v1
A Multimodal Atlas Reveals the Anatomical Distribution of Medium Spiny Neuron Subtypes and a Novel RGS6+ Population in the Primate Striatum https://www.biorxiv.org/content/10.1101/2025.11.16.688724v1
A Multimodal Atlas Reveals the Anatomical Distribution of Medium Spiny Neuron Subtypes and a Novel RGS6+ Population in the Primate Striatum https://www.biorxiv.org/content/10.1101/2025.11.16.688724v1
A Multimodal Atlas Reveals the Anatomical Distribution of Medium Spiny Neuron Subtypes and a Novel RGS6+ Population in the Primate Striatum #NeuroDegeneration 🧪🧠 https://www.biorxiv.org/content/10.1101/2025.11.16.688724v1
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Check out our new paper, that reveals both the striking generality of cortical circuit organization, but also what we think are key differences in the scales of local excitatory and inhibitory networks across cortical areas. www.jneurosci.org/content/45/1...
Local Differences in Network Organization in the Auditory and Parietal Cortex, Revealed with Single Neuron Activation
The structure of local circuits is highly conserved across the cortex, yet the spatial and temporal properties of population activity differ fundamentally in sensory-level and association-level areas....
jneurosci.org