An amazing feat of developmental systems neuroscience resulting in a paper directly probing such a fundemental question of nature vs nurture. Congratulations @matteoguardamagna.bsky.social et al. 🎉🎉

Matteo Guardamagna@matteoguardamagna.bsky.social · 7mo ago

1/7 🧠 My journey into development begins with this work and question: how does the brain's spatial navigation system develop? We found that the neural networks for spatial navigation (tori and rings) are preconfigured and only later anchor gradually to the world with experience! 🧵

Do #PlaceCells that sit next to each other also represent nearby places in the world? 🧠🤝🗺️ www.pnas.org/doi/10.1073/...

CA1 + place cell topography = ❓❓❓ Amazing work from @torsteinslettmoen.bsky.social on getting his PhD paper published! Happy to have been able to contribute 🗺️🧠🐁🔬

Edvard I Moser@edvardmoser.bsky.social · 8mo ago

A half-century old question may have its final answer. Using high-resolution #Mini2P microscopes, we find no evidence of local topography in #PlaceCells. Place fields of neighbouring cells are no more similar than those of randomly selected cells. 🧠🗺️ Out now in @pnas.org www.pnas.org/doi/10.1073/...

🚀 New preprint from the lab! Our first foray into the subiculum uses in vivo whole-cell recordings to show that dendritic plateaus are a prominent, learning-dependent signaling mode of subicular neurons. Feedback is welcome! www.biorxiv.org/content/10.6...