The Moser Group is presenting our work on Wednesday afternoon at #FENS2026! •Mechanism for L-R sweeps •Attention modulation of sweeps •Grid/place remapping rules & dynamics •”Mega torus” as a hi-capacity memory space •Moving the grid bump •Development of tori & rings •RSC/HC pops. in a spatial task

Congratulations to @weijianzong.bsky.social, our Neurophotonics group leader and a new 2026 #FENSKavliScholar. He builds the #Mini2P microscopes that let us watch the living brain at work. @fens.org @kavlifoundation.org @alleninstitute.org @ntnudiscovery.bsky.social @fkne-scholars.bsky.social

@fkne-scholars.bsky.social · 4w ago

Welcome to the 15 newly selected #FENSKavliScholars! Representing 12 European countries, they join a network of 30 Scholars across 21 countries and 25 nationalities. 🧠✨With thanks to @fens.org, @kavlifoundation.org, @alleninstitute.org and our partners for supporting FKNE. h1.nu/1t8Lw

Out now in @science.org by @emreyaksi.bsky.social, Anh-Tuan Trinh and colleagues at the Kavli Institute in Trondheim: Hierarchical sensory processing in zebrafish thalamocortical-like circuits doi.org/10.1126/scie...

Hierarchical sensory processing in zebrafish thalamocortical-like circuits

Thalamocortical projections shape the functional regionalization and parallel sensory computations across the mammalian cortex. However, the principles of thalamocortical computations in non-mammalian...

doi.org

Are we born with a sense of space? 🧠 A new preprint from the #MoserGroup suggests that the brain’s internal navigation system 🍩 begins forming before young animals actively explore the world. 🧵(1:5) Have a look at the preprint here 👇 www.biorxiv.org/content/10.6...

1/6 Do neighboring #PlaceCells in #Hippocampus CA1 map neighboring locations in space? 🧠🗺️ Is there micro-scale spatial topography in the hippocampus? See our latest paper from @kavlintnu now out in @pnas.org www.pnas.org/doi/10.1073/...

Place cells in CA1 lack topographical organization of firing locations | PNAS

Topography is a well-described and well-known concept for cortical organization in primary sensory and motor cortices of mammalian brains. Similar ...

pnas.org

Edvard I Moser@edvardmoser.bsky.social · 6mo ago

A half-century old question may have its final answer. Using high-resolution #Mini2P microscopes, we find no evidence of local topography in #PlaceCells. Place fields of neighbouring cells are no more similar than those of randomly selected cells. 🧠🗺️ Out now in @pnas.org www.pnas.org/doi/10.1073/...

Do #PlaceCells that sit next to each other also represent nearby places in the world? 🧠🤝🗺️ www.pnas.org/doi/10.1073/...

Applications are now open for the summer school: 𝐌𝐚𝐭𝐡𝐞𝐦𝐚𝐭𝐢𝐜𝐚𝐥 𝐌𝐞𝐭𝐡𝐨𝐝𝐬 𝐢𝐧 𝐂𝐨𝐦𝐩𝐮𝐭𝐚𝐭𝐢𝐨𝐧𝐚𝐥 𝐍𝐞𝐮𝐫𝐨𝐬𝐜𝐢𝐞𝐧𝐜𝐞 🧠 Apply before March 15: www.compneuronrsn.org 📍 Located in beautiful Eresfjord 🇳🇴 🗓️ Between July 6-24 Supported by the @kavlifoundation.org In collaboration with @kavlintnu.bsky.social

Mathematical Methods in Computational Neuroscience

Summer school in Eresfjord, Norway (July 8th - 26th, 2024)

compneuronrsn.org

How does the 🧠-map choose what to sample? Preprint: #Sweeps in #gridcells act as attention-like signal, dynamically biasing the map towards behaviourally relevant locations. By @mschellenberger.bsky.social @azvollan.bsky.social @m-bmoser.bsky.social @edvardmoser.bsky.social + @rjgardner.bsky.social

Edvard I Moser@edvardmoser.bsky.social · 6mo ago

The hippocampal map has its own attentional control signal! Our new study reveals that theta #sweeps can be instantly biased towards behaviourally relevant locations. See 📹 in post 4/6 and preprint here 👉 www.biorxiv.org/content/10.6... 🧵(1/6)

🎉 Gratulerer til vår kollega Magnar Bjørås, kåret til Årets trønder! Ved Kavli-instituttet er vi stolte over Magnars banebrytende forskning på sjeldne sykdommer som barnedemens - forskning som gir håp der det trengs aller mest. Les saken på NRK:

Årets trønder og Årets hverdagshelt 2025 er kåret

Hun hjelper barn i konfliktområder, mens han forsker på barnedemens. Fredag blir de hedret i Olavshallen.

nrk.no

🧠🔬 NOK 12M to #META2P from Kavli & SINTEF! Neurophotonics PI @weijianzong.bsky.social at @kavlintnu.bsky.social is together with NorFab #MiNaLab PI Christopher Dirdal at SINTEF awarded NOK 12 million by the Research Council of Norway to develop the next generation of two-photon microscopes (1:2)

Today, Harald V King of Norway opened the Norwegian Health Association Centre for Dementia Research, at the Kavli Institute in Trondheim.

QQ11: RSC is using the HPC spatial code for good! We observed retrosplenial populations encode task structure when behaviourally relevant cues were present in a hippocampal-dependent spatial task.

QQ10: We see minute-scale population drift, not only in LEC, but also MEC and CA1 in conditions with minimal external stimuli, i.e., when mice are head-fixed on a wheel in darkness! @anelautrup.bsky.social

Poster QQ9: Theta sweeps can track moving bait and go backwards! In our poster, we describe situations in which the stereotypic left-right alternating theta sweep pattern is modulated to cover behaviorally relevant space @azvollan.bsky.social

QQ8: What drives the left–right alternation of theta sweeps? Whether a central-pattern generator (CPG)-like circuit is involved? @rajatsxn.bsky.social

QQ7: How do MEC ultraslow dynamics vary across behavioral states. In free foraging, population dynamics organize in ultraslow sequences while in NREM sleep they present as synchronous oscillations.

QQ6: By combining large high-NA objective, wide-angle MEMS scanning, SiPM detection, and multi-beam multiplexing, this new 2P miniscope (Mini10K) enables cellular-resolution imaging of thousands of neurons in freely moving mice, surpassing current FOV and throughput limits.

QQ5: What is the developmental timeline of the low-dimensional manifolds of the entorhinal cortex? Rings and tori organize at P9-P10 before major sensory-motor milestones, coinciding with other major shifts in MEC cortical dynamics. @me

QQ4: QQ4: We study population dynamics across the spatial navigation circuit as a rat moves between 4 rooms. With 4 NPX probes in CA, MEC/PaS, SUB, and dPreSUB, we see how maps switch at a fine timescale and track when each region settles into the correct representation. @jocarpenter.bsky.social

QQ3: We observe hexagonal grid cells even in environments with elevation changes! The hexagonal pattern is cleaner on the surface of a ramp and on a dome seen from above, and more distorted on a cone seen from above.

QQ2: Where are the grid cells and if so, how many? We find that grid cells form a discrete "hot spot" segregated from other functional cell types in the superficial layers of MEC and PaS. @martipof.bsky.social

Still at SfN on the last day? During the morning session on the 19th, 8:00AM - 12:00PM, come check out our posters from the Moser, Zong, and Gonzalo Cogno groups in row QQ ('Grid cells and spatially modulated cells'). Ephys, imaging, remapping, development, sweeps and more! 🧠 Detailed thread below 👇

SFN 2025 let’s gooo!! Moser group posters are held Wednesday morning (QQ), so if you’re leaving early feel free to come find us to chat :)

Thank @kavlintnu.bsky.social, the research council of Norwayfor the continues support of our work! We will provide more useful tools like #mini2p to the neuroscience!

Check out this new preprint from @clykken.bsky.social and the Moser Group: Independent phase-shifts across MEC grid modules can generate a vast diversity of hippocampal codes — revealing the mechanism that enables episodic memory. 👇

@clykken.bsky.social · 10mo ago

1/8 How can the brain create countless unique memories using a single, universal metric of space? We’ve been waiting for the answer to this for two decades! Read it here: www.biorxiv.org/content/10.1...

🔁 Fascinating new preprint from the Moser Group! How does the hippocampus achieve its vast memory capacity? 🧠 The answer lies in the flexible combinatorics of grid cells. 📄 Read more in the thread by @edvardmoser.bsky.social 👇

Edvard I Moser@edvardmoser.bsky.social · 10mo ago

1/5 How does the brain turn the low-dimensional, universal grid cell metric into the rich, diverse codes needed for memory in hippocampal place cells? 🧵 Preprint link 👇 www.biorxiv.org/content/10.1...

Our new paper out now in Science explores how neural activity in the lateral entorhinal cortex (LEC) *drifts* over time - and *jumps* at key boundaries - to help organize events in memory. 🔗 www.science.org/doi/10.1126/... Here's a quick summary of what we found 🧵👇

Event structure sculpts neural population dynamics in the lateral entorhinal cortex

Our experience of the world is a continuous stream of events that must be segmented and organized at multiple timescales. The neural mechanisms underlying this process remain unknown. In this work, we...

science.org

Edvard I Moser@edvardmoser.bsky.social · last yr.

Your brain doesn’t just passively track time ⏳ - it structures it. In @Science.org we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2) 👉 www.science.org/doi/10.1126/...

... and those jumps act like barcodes - distinct neural signatures that help the brain tag and retrieve memories. @beneuroscience.bsky.social @clykken.bsky.social @nachopolti.bsky.social @m-bmoser.bsky.social @edvardmoser.bsky.social‬ at the @kavlintnu.bsky.social

Edvard I Moser@edvardmoser.bsky.social · last yr.

Your brain doesn’t just passively track time ⏳ - it structures it. In @Science.org we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2) 👉 www.science.org/doi/10.1126/...

Delightful visit and dinner today in Trondheim and more tomorrow: thanks again @m-bmoser.bsky.social and @edvardmoser.bsky.social for giving me a chance to present our new data on social and sickness behavior. Looking forward to hearing more about the amazing projects at @kavlintnu.bsky.social

May-Britt Moser@m-bmoser.bsky.social · last yr.

Thank you so much Catherine @dulaclab.bsky.social for a thought-provoking and an eminent talk today at @kavlintnu.bsky.social @edvardmoser.bsky.social

Thank you so much Catherine @dulaclab.bsky.social for a thought-provoking and an eminent talk today at @kavlintnu.bsky.social @edvardmoser.bsky.social