The Vallee Foundation
@valleefoundation.bsky.social
To promote a collegial community of international scientists, to enhance scientific collaboration and communication, and to advance medical education and biomedical research.
Congratulations to Vallee Scholar Madeline Lancaster who has won the 2026 Suffrage Science Award which celebrates the scientific achievements of women in science. mrclmb.ac.uk/news-events/...
Madeline Lancaster wins 2026 Suffrage Science Award | MRC Laboratory of Molecular Biology
Madeline Lancaster, Joint Head of the LMB’s Cell Biology Division, has been recognised in the 2026 Suffrage Science Awards.
mrclmb.ac.uk
Vallee Scholar Andela Šarić's group will play a central role in a new research project funded by the Austrian Science Fund (FWF) to investigate the biology of the germline, i.e., the cells from which egg cells and sperm cells originate. ista.ac.at/en/news/egg-...
Egg Cells & Sperm: New Emerging Fields Project
The Institute of Science and Technology Austria (ISTA) is part of a new research project funded by the Austrian Science Fund (FWF) with 5.1 million Euro as part of the excellent=austria initiative. Ti...
ista.ac.at
Interesting news out of Ricardo Mallarino's (Vallee Scolar 2021) lab: neurosciencenews.com/agouti-gene-...
Social Competition Can Turn Nurturing Dads into Neglectful Ones - Neuroscience News
A study identifies the Agouti gene as a molecular "off switch" for paternal care in the brain, influenced by environmental social competition.
neurosciencenews.com
Congratulations to Vallee Scholar Aashish Manglik who has just been named a Vilcek Prize winner: vilcek.org/prizes/prize...
Aashish Manglik - Vilcek Foundation
Aashish Manglik uncovers the conformational complexity of G protein–coupled receptors, fundamentally reshaping scientists’ understanding of cellular signaling.
vilcek.org
interesting article from Vallee Scholar Shigeki Watanabe (Johns Hopkins) providing clues to Parkinson's disease: www.sciencedaily.com/releases/202...
New brain imaging breakthrough reveals clues to Parkinson’s
A high-speed “zap-and-freeze” method is giving scientists their clearest view yet of how brain cells send messages. By freezing tissue at the instant a signal fires, researchers revealed how synaptic ...
sciencedaily.com
Congratulations to VVP Tony Hyman who is to become the next EMBL Director General nachrichten.idw-online.de/2025/11/27/a...
Anthony Hyman to become next EMBL Director General
nachrichten.idw-online.de
Vallee Scholar Shigeki Watanabe and his colleagues at Johns Hopkins Medicine say they have used a “zap-and-freeze” technology to watch hard-to-see brain cell communications in living brain tissue from mice and humans www.hopkinsmedicine.org/news/newsroo...
‘Zap-and-Freeze’ Technique Successfully Used to Watch Human Brain Cell Communication
hopkinsmedicine.org
Interesting research that new light on ancient wolves from Vallee Scholar Pontus Skoglund: www.labrujulaverde.com/en/2025/11/u...
Unusual Discovery of Wolf Remains Thousands of Years Old on a Remote Baltic Island: They Lived with Humans, Shared Their Food, and Could Only Have Arrived by Boat
The relationship between humans and prehistoric canids, a fundamental chapter in the history of our species, has just become significantly more complex. A multidisciplinary team of scientists has anno...
labrujulaverde.com
And Vallee Scholar Michael Yartsev is discovering how bats learn, remember and form social bonds: www.hhmi.org/news/bat-res...
How Bat Research Sheds Light on the Brain and Behavior | HHMI
HHMI scientists Michael Yartsev and Gerald Carter are uncovering how bats learn, remember, and form social bonds — findings that could reshape how we understand our own brains and behaviors.
hhmi.org
Two new papers from Vallee Scholar Johannes Gräff on memory consolidation: www.nature.com/articles/s41... onlinelibrary.wiley.com/doi/epdf/10....
Cell-type- and locus-specific epigenetic editing of memory expression - Nature Genetics
CRISPR-based epigenetic editing is used in a cell-type-specific, locus-restricted and temporally controllable manner in the adult mouse brain to modulate memory expression.
nature.com
and from Vallee Scholar Mackenzie Mathis: www.cell.com/cell/fulltex...
Decoding the brain: From neural representations to mechanistic models
Understanding how the brain works has been a formidable challenge in neuroscience, but advances at the computational level are now driving us closer. This perspective discusses core concepts of neural...
cell.com
Interesting study from Vallee Scholar Melissa Harrison: medicalxpress.com/news/2025-10...
Fruit fly study reveals genetic targets for rare childhood brain cancer treatment
Using fruit flies, University of Wisconsin–Madison researchers have developed a new model for investigating the genetic drivers of a rare but aggressive brain tumor in children. The work has already i...
medicalxpress.com
Vallee Scholar Lisa Giocomo reveals how aging affects special memory news.ssbcrack.com/study-reveal...
Study Reveals How Aging Affects Spatial Memory in Mice - SSBCrack News
In a groundbreaking study, researchers at Stanford Medicine have discovered critical insights into how spatial memory declines with aging, revealing potential
news.ssbcrack.com
Vallee Scholar Daniel Jarosz becomes first senior associate dean for basic science at Stanford University. med.stanford.edu/news/all-new...
Dan Jarosz becomes first senior associate dean for basic science
Jarosz is the inaugural appointment to the newly created position, which will support basic science faculty throughout the Stanford School of Medicine.
med.stanford.edu
Vallee Scholar Madeline Lancaster appointed Joint Head of the Cell Biology Division at MRC Laboratory of Molecular Biology in Cambridge: www2.mrc-lmb.cam.ac.uk/madeline-lan...
Madeline Lancaster appointed Joint Head of the Cell Biology Division - MRC Laboratory of Molecular Biology
Group Leader Madeline Lancaster joins Manu Hegde to oversee the LMB’s Cell Biology Division.
www2.mrc-lmb.cam.ac.uk
Vallee scholar Rickard Sandberg, professor of Molecular Genetics, member of the Nobel Committee, is interviewed by Sharon Jåma about this year's Nobel prize. www.youtube.com/watch?v=5fxn...
“A fundamental discovery about the principle that keeps our immune system in check” | Medicine prize
YouTube video by Nobel Prize
youtube.com
Vallee Scholar Weizhe Hong has a new paper out in Nature which shows a remarkable convergence of neuroscience and artificial intelligence: www.eurekalert.org/news-release...
First-of-its-kind study finds striking parallels between biological and artificial intelligence during social interaction
A first-of-its-kind study reveals that when mice interact socially, specific brain cell types synchronize in "shared neural spaces," and AI agents develop analogous patterns when engagi...
eurekalert.org
Vallee Scholar Bob Datta is on Instagram with an important message about Alzheimer's research www.instagram.com/reel/DKzuKjR...
Congratulations to Vallee Fdtn Director Wade Harper (HMS) on $5M+ Fox Fdtn grant for PD research & collab with VVPs Brenda Schulman, Ulrich Hartl (MPI), Judith Frydman (Stanford) among others in international, multidisciplinary Collaborative Research Network (CRN) hms.harvard.edu/departments/...
hms.harvard.edu
Many congratulations to Vallee Scholar Tanmay Bharat, Group Leader in the MRC Lab of Molecular Biology, who has been awarded the EMBO Gold Medal for his research in the field of structural microbiology! www2.mrc-lmb.cam.ac.uk/tanmay-bhara...
Tanmay Bharat awarded EMBO Gold Medal - MRC Laboratory of Molecular Biology
Tanmay Bharat, Group Leader in the LMB’s Structural Studies Division, received EMBO’s Gold Medal in recognition of his work on prokaryotic surface molecules.
www2.mrc-lmb.cam.ac.uk
Congratulations to Dr Danelle Devenport (Vallee Scholar 2014), Shirley M. Tilghman Professor of Molecular Biology at Princeton U, who received the President's Award for Distinguished Teaching at Commencement ceremonies on Tuesday, May 27 www.princeton.edu/news/2025/05...
Faculty members receive President’s Awards for Distinguished Teaching
Professors Rebecca Carey, Gabriel Crouch, Danelle Devenport and Nathaniel Fisch received the President’s Award for Distinguished Teaching at Commencement ceremonies May 27.
princeton.edu
So happy for our Vallee Visiting Professor Wolfang Baumeister who has just been named the Shaw Prize in Life Science and Medicine: erc.europa.eu/news-events/...
ERC grantee wins the Shaw Prize in Life Science and Medicine
2025 Shaw Prize honours ERC-funded research in molecular imaging
erc.europa.eu
Research teams working with Tyler Jacks (VVP 2016) (MIT) and William Freed-Pastor (Dana-Farber and MIT) have a new article in Science in which they show how a class of proteins expressed in pancreatic cancer cells, could serve as targets for immune cell therapy. www.science.org/doi/10.1126/...
Pancreatic cancer–restricted cryptic antigens are targets for T cell recognition
Translation of the noncoding genome in cancer can generate cryptic (noncanonical) peptides capable of presentation by human leukocyte antigen class I (HLA-I); however, the cancer specificity and immun...
science.org
Feng Zhang (Vallee Scholar 2013) and his team at the McGovern and Broad Institutes have reengineered a compact RNA-guided enzyme they found in bacteria into an efficient, programmable editor of human DNA. See their paper in Nature Biotch www.nature.com/articles/s41...
Evolution-guided protein design of IscB for persistent epigenome editing in vivo - Nature Biotechnology
A combination of engineering approaches is used to improve the function of IscB for a variety of editing activities in vivo.
nature.com
Elena Conti, PhD (Vallee Visiting Prof 2019), Director, MPI of Biochemistry in Martinsried, shares this year’s prestigious Jung Prize for Medicine with Jorn Piel, MD, ETH Zurich. thevalleefoundation.org/news/elena-c...
Elena Conti wins Jung Prize for Medicine | The Vallee Foundation
thevalleefoundation.org
Congratulations to Feng Zhang (Vallee Scholar 2013) (Broad Inst, MIT, HHMI Investigator) who received an honorary doctorate from Duke University on Sunday! today.duke.edu/2025/04/duke...
Duke to Award Three Honorary Degrees at 2025 Commencement Ceremony | Duke Today
today.duke.edu
Chris Mason (Vallee Scholar 2014) at Weil Cornell Medicine is one of the PIs seeking to catalog the normal human virome, the immense ecosystem of viruses that lives in and on us. news.weill.cornell.edu/news/2025/04...
A VAST New View of Viruses
A major new effort at Weill Cornell Medicine seeks to catalog the normal human virome, the immense ecosystem of viruses that lives in and on us.
news.weill.cornell.edu
Vallee Scholar (2021) Ricardo Mallarino (Princeton) has been using the sugar glider (Petaurus breviceps) to investigate immunological defense strategies. Check out his recent paper in Science www.science.org/doi/10.1126/....
Cathelicidin antimicrobial peptides mediate immune protection in marsupial neonates
Cathelicidin antimicrobial peptides protect marsupial neonates by mediating immune defense against pathogens.
science.org
Excited to share our exploration @naturemethods.bsky.social into new horizons opening up in the era of low cost sequencing! 🔥 Deeper sequencing at WGS scale for PPM sensitivity of tumor informed MRD 🔥Duplex sequencing at WGS scale for plasma only exploration of ctDNA Check out thread 👇
Alex@alexpellancheng.bsky.social · last yr.What happens when sequencing costs go ⏬ ? Imagination and new opportunities go ⏫ @landau.bsky.social Let's look at what you can do when you perform deep WGS on cfDNA for cancer detection. Our recent work with the @UltimaGenomics platform 🧵👇 Lets goooo!! rdcu.be/ehkUb
Join us at the Royal Society in London 14 November for a day on Ancient genomes, human biology and medicine! Many slots are reserved for talks from submitted abstracts related to the topic, alongside speakers Svante Pääbo, Priya Moorjani, @mathiesoniain.bsky.social and Lluis Quintana-Murci.
Genetics Society UK@gensocuk.bsky.social · last yr.Registration now open! Join us for our Autumn Meeting: “Ancient genomes: perspectives on human biology and medicine” organised by @janetk.bsky.social and @pontus-skoglund.bsky.social. Explore how ancient DNA informs migration, adaptation & disease. genetics.org.uk/events/ancie...
