Ok, time to feel old – for a good cause 😃 I was in the middle of my PhD when our journal was launched. An online-only journal at a time when most others were not. This is by definition a VERY special issue. Have a look at what papers we're looking for and be a part of the future of the journal!

Structural Biology Communications@actacrystf.iucr.org · last wk.

We're celebrating 20 years of Acta Crystallographica Section F!🎉🥳 Join us by contributing to our celebratory collection of articles, which is now open for submissions! Find out more at journals.iucr.org/special_issu...

Some questions for our structural biology community: What protocols do you think would be useful to have? Do you prefer to watch step-by-step videos, or follow written instructions? Of course, not everything has to be a video, but certain workflows are simply best documented on video #protocols

Structural Biology Communications@actacrystf.iucr.org · 6d ago

A new type of article for Acta F: Protocols The purpose of this new category is to provide to the reader procedures that are sufficiently detailed so other researchers can reproduce the described workflow. Find out more in 'Show me how it's done: introducing Protocols': doi.org/10.1107/S205...

A new type of article for Acta F: Protocols The purpose of this new category is to provide to the reader procedures that are sufficiently detailed so other researchers can reproduce the described workflow. Find out more in 'Show me how it's done: introducing Protocols': doi.org/10.1107/S205...

We're celebrating 20 years of Acta Crystallographica Section F!🎉🥳 Join us by contributing to our celebratory collection of articles, which is now open for submissions! Find out more at journals.iucr.org/special_issu...

A new type of article for Acta F: Protocols The purpose of this new category is to provide to the reader procedures that are sufficiently detailed so other researchers can reproduce the described workflow. Find out more in 'Show me how it's done: introducing Protocols': doi.org/10.1107/S205...

We're celebrating 20 years of Acta Crystallographica Section F!🎉🥳 Join us by contributing to our celebratory collection of articles, which is now open for submissions! Find out more at journals.iucr.org/special_issu...

A crystal structure of PLpro exhibits Ubl2 in two distinct conformations: the well characterized closed state, where Ubl2 is positioned near the PLpro domain, and an as yet uncharacterized open state #SARSCoV2 #PapainLikeProteases #Ubl2Domain doi.org/10.1107/S205...

A new crystal structure of ApePCNA1 and the newly solved structure of the ApePCNA2 homotrimer allowed modeling of the ApePCNA1–ApePCNA2–ApePCNA3 heterotrimer #AeropyrumPernix #DNAReplication #ProliferatingCellNuclearAntigens doi.org/10.1107/S205...

The crystal structure of GABA aminotransferase from A. thaliana and structural comparison supports the conclusion that it belongs to the class III aminotransferase family #ArabidopsisThaliana #CrystalStructure #GABAAminotransferase doi.org/10.1107/S205...

The molecular interactions of the insomnia drug vorenorexant with human orexin receptors were analysed through crystal structure analysis and docking simulations #Vornorexant #OrexinReceptors #CrystalStructure doi.org/10.1107/S205...

This structure of macrophage migration inhibitory factor is a contribution to our cross-journal Early Career Scientists in Structural Science special issue. Find out more at journals.iucr.org/early-career... #SSGCID #MacrophageMigrationInhibitoryFactor doi.org/10.1107/S205...

July issue is out now! journals.iucr.org/f/issues/202... This month's cover star is the type VI secretion system adaptor protein Tla3 from Pseudomonas aeruginosa strain UCBPPPA14. Find out more about this structure at doi.org/10.1107/S205...

📢 Applications open! Join the 9th International School on Biological Crystallization in Granada Gain hands-on experience + learn from leading experts in macromolecular crystallization. Don’t miss this opportunity! 🔗 www.isbcgranada.org #Crystallography #StructuralBiology #ScienceTraining

The structure of spectrin-like repeat 24 of human dystrophin is in excellent agreement with the AlphaFold model, supporting AlphaFold modeling of all 24 dystrophin spectrin-like repeats #Dystrophin #SpectrinLikeRepeat #DuchenneMuscularDystrophy doi.org/10.1107/S205...

The structure of a complex between human RAGE ectodomain and S100A6 variant Y84C provides a possible model for S100 covalent homodimerization that is fully compatible with RAGE binding #S100Proteins #Cysteines #CovalentHomodimerization doi.org/10.1107/S205...

The first structure of a cold-active arginase reveals a modest reduction in structural rigidity associated with cold adaptation #ColdActiveEnzymes #Arginases #XRayCrystallography doi.org/10.1107/S205...

New paper out in @actacrystf.iucr.org! We benchmarked cryoSPARC for amyloid helical reconstruction: ease of use over RELION, but amyloid-specific development still needed & software interoperability remains a problem. @landerlab.bsky.social Kelly Lab @scripps.edu doi.org/10.1107/S205...

Acetylation-mimicking K214Q and K216Q variant structures of Escherichia coli glucokinase showed that acetylation mimics impaired activity and produced domain shifts #Glucokinases #LysineAcetylation #AcetylationMimickingMutations doi.org/10.1107/S205...

Structural and enzymatic characterization of an Asp49 phospolipase A2 (PLA2) from Lachesis muta expands our understanding of structure–function relationships among viperid PLA2s #SnakeVenomPhospholipaseA2 #LachesisMuta #ProteinOligomer doi.org/10.1107/S205...

The June issue is out! journals.iucr.org/f/issues/202... The cover illustration - Plasmodium vivax macrophage migration inhibitory factor - is from an article forming part of our Early Career Scientists in Structural Science special issue. Find out more and submit: journals.iucr.org/early-career...

Thank you to my coauthor Stefania Hanau and to @actacrystf.iucr.org 6590 downloads is very satisfying. Thank you to all those readers.

In our latest episode of Interviews With Authors, we discussed PentatricoPeptide Repeat (PPR) proteins, their roles in RNA binding, use in protein design and other things, and I'd like to share some highlights. What are PPR proteins and why do they matter, you may ask? Anuradha has the answers:

Structural Insights into PPR Proteins and RNA Recognition

YouTube video by International Union of Crystallography

youtube.com

It was lovely to chat with Anu and @charliebondxray.bsky.social about PPR proteins, their RNA binding modes and awesome modularity. Please watch, give the IUCr a thumbs up, and add some comments when you have a minute! What would you like to see in these interviews?

Structural Biology Communications@actacrystf.iucr.org · 3mo ago

In the latest in our Interviews With Authors series, the Acta F Section Editors talk to Anuradha Pullakhandam and Charlie Bond about their review on 'Structures of pentatricopeptide repeat proteins'. Read the article at journals.iucr.org/f/issues/202... www.youtube.com/watch?v=nYcF...

In the latest in our Interviews With Authors series, the Acta F Section Editors talk to Anuradha Pullakhandam and Charlie Bond about their review on 'Structures of pentatricopeptide repeat proteins'. Read the article at journals.iucr.org/f/issues/202... www.youtube.com/watch?v=nYcF...

Structural Insights into PPR Proteins and RNA Recognition

YouTube video by International Union of Crystallography

youtube.com

New issue is out! journals.iucr.org/f/issues/202... On the cover: the atomic structure of human dystrophin spectrin-like repeat 24 determined at 2.14 Å resolution journals.iucr.org/f/issues/202...

New issue is out! journals.iucr.org/f/issues/202... On the cover: the atomic structure of human dystrophin spectrin-like repeat 24 determined at 2.14 Å resolution journals.iucr.org/f/issues/202...

Modifying the bacterial strain led to cleaner bacterial expression of a synthetic BRIL antibody that facilitates protein structure determination via both crystallography and cryo-EM #CryoEM #XRayCrystallography #BRIL doi.org/10.1107/S205...

High-resolution structures of α-bCA2 with sulfonamide derivatives provides experimentally supported information defining their binding mode and supporting inhibitor optimization #CarbonicAnhydraseII #SulfonamideInhibitors #XRayCrystallography doi.org/10.1107/S205...

An acylated GLP-1/GIP analogue peptide forms a uniquely porous spiral crystal structure composed of clockwise-ascending monomers in a square pattern #GLP1 #Peptides #Crystallization doi.org/10.1107/S205...

A comprehensive survey catalogues all pentatricopeptide repeat protein crystal structures, analysing their crystallographic properties, structural features and contributions to understanding function #PentatricopeptideRepeatProteins #RNARecognition doi.org/10.1107/S205...