Check out our new review with @mfarjo.bsky.social on what we know about the functional and evolutionary consequences of virus-virus interactions within viral populations, out now in @annualreviews.bsky.social: www.annualreviews.org/content/jour... Hope you like it!

Heterogeneity and Collective Interactions Within Viral Populations

The existence of viruses as obligate intracellular parasites with high mutation rates sets them apart from other forms of life in fundamental ways. Frequent errors in replication and assembly processe...

annualreviews.org

Excited to announce that we are moving the lab to Minneapolis to join the University of Minnesota Department of Microbiology & Immunology and Institute on Infectious Diseases this summer!! We will be hiring so please reach out if interested in viral evolution, viral immunology, etc.!!

Open #postdoc fellowship in my group. Virus replication and cryo-ET. Projects can be tailored to ambitious candidates with diverse backgrounds, so don't hold back from applying! DM for more info. Deadline 22May. Apply here: umustipendie.varbi.com/en/what:job/... #virus #virology #teamtomo #cryoEM

Do you have a passion for communications and engagement? Do you think viruses are cool? We are recruiting maternity cover for our Comms and Engagement Lead here @cvrinfo.bsky.social, the largest virus research centre in the UK. Hybrid working options, generous salary, great people. Please share!

Finally, it's up on bioRxiv! It's been a rewarding journey shaping this story. My deepest gratitude to @vignuzzilab.bsky.social and @christopherbrooke.bsky.social for their incredible support, and to the @mcbillinois.bsky.social & @astar-idlabs.bsky.social for enabling this research

Check out @mfarjo.bsky.social's new preprint where she uses a simulation-based approach to explore the evolutionary consequences of genetic mixing through co-infection for segmented viruses: www.biorxiv.org/content/10.1... hope you like it!

The fitness consequences of coinfection and reassortment for segmented viruses depend upon viral genetic structure

Cellular coinfection between multiple virions is a common feature of viral infections. The collective virus-virus interactions enabled by these coinfections can influence the fitness of viral populati...

biorxiv.org

Excited for my first bluesky post announcing TWO openings for tenure track positions in virology! I am chair of the search committee and with a new department head Mike Gale we are in an exciting building phase. Please share with anyone who might be interested: hr.myu.umn.edu/jobs/ext/365...

Check out @joelrc.bsky.social 's new preprint examining how the seasonal H1N1 and H3N2 lineages of IAV differ in their ability to antagonize IFN induction and signaling, and how these phenotypes have evolved over decades of circulation in humans: www.biorxiv.org/content/10.1...

Seasonal influenza A virus lineages exhibit divergent abilities to antagonize interferon induction and signaling

bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

biorxiv.org

Fantastic article on the social lives of viruses 🦠 🧪by @carlzimmer.bsky.social featuring work by @asherleeks.bsky.social and many others www.quantamagazine.org/viruses-fina.... Glad to be wading into this field thanks to @nanamikubota.bsky.social

Viruses Finally Reveal Their Complex Social Life | Quanta Magazine

New research has uncovered a social world of viruses full of cheating, cooperation and other intrigues, suggesting that viruses make sense only as members of a community.

quantamagazine.org

Natural variation in neuraminidase activity influences the evolutionary potential of the seasonal H1N1 lineage hemagglutinin https://www.biorxiv.org/content/10.1101/2024.03.18.585603v1

Natural variation in neuraminidase activity influences the evolutionary potential of the seasonal H1N1 lineage hemagglutinin https://www.biorxiv.org/content/10.1101/2024.03.18.585603v1

The antigenic evolution of the influenza A virus hemagglutinin (HA) gene poses a major challenge for

biorxiv.org

Very glad to contribute to this collaboration exploring the role of truncated proteins produced by Influenza DelVG during infection.

Asher Leeks@asherleeks.bsky.social · 2y ago

Very exciting finding: most viruses produce large deletion mutants (DVGs), some of which can spread as cheats. In flu, DVGs often delete > 80% of the genome, so we typically assume they don't encode functional proteins... doi.org/10.1093/nar/... (1/2)

Announcing the Social Lives of Viruses 2024! Do you study social evolution in viruses? Do you want to? Join us in Puerto Rico this June for a 50-person meeting dedicated to viral sociality. All costs covered. Apply here: forms.gle/sHTEcHJjryDh... #ViroSky #MicroSky #EvoSky #SocialViruses

I am very glad to see this out, beautiful work, congrats @mfarjo.bsky.social 🥳🥳

Chris Brooke@christopherbrooke.bsky.social · 3y ago

Excited to *finally* have @mfarjo.bsky.social 's fantastic paper on SARS-CoV-2 within-host evolutionary dynamics during acute infection published at JVI: journals.asm.org/doi/10.1128/...