Congratulations to Dr. Adam Kundishora, CHOP pediatric neurosurgeon, on receiving funding support from CHOP's Young Leadership Alliance for his proposal on characterizing vascular malformations! ⭐

Our own Dr. Yi Xing et. al developed a low-cost long-read RNA sequencing platform that revealed disease-causing variants in 88 children with a range of #RareDisorders —including a patient whose condition went undiagnosed for a decade. Read more: www.research.chop.edu/cornerstone-...

⭐ Don't forget to cast your vote for CHOP in #STATMadness 2026! 2 of our research studies advanced to the next round: the world’s first personalized gene therapy for a rare disease, and a study of childhood smartphone ownership and its association with depression + obesity. Vote before 3/23!

2026 STAT Madness

STAT Madness 2026

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❤️An important message from our CSO, EVP, & team captain Dr. Sue Furth! Dr. Furth + the Research Institute team will be joining April's I ♥ CHOP Run, Walk & Virtual Challenge presented by Philadelphia Insurance Companies. Join us, support, or learn more: chop.donordrive.com/teams/CHOPRe...

Congratulations to @ahrensnicklas.bsky.social (@chopresearch.bsky.social/ @pennmedicine.bsky.social) on her election to @the-asci.org! Learn more about Dr. Ahrens-Nicklas & her work here➡️ tinyurl.com/msv9skj4

Congratulations to @romberglab.bsky.social (@chopresearch.bsky.social/ @pennmedicine.bsky.social) on his election to @the-asci.org! Learn more about Dr. Romberg & his work here➡️ tinyurl.com/432m24m9 @i3h-upenn.bsky.social

Congratulations to @kiranmusunuru.bsky.social (@penngenetics.bsky.social/ @penncvi.bsky.social) & @ahrensnicklas.bsky.social (@chopresearch.bsky.social) on being named to the @time.com 100 List of the World’s Most Influential Leaders in Health! tinyurl.com/6w45skp2

Congratulations to Maria Mascarenhas (@childrensphila.bsky.social/ @chopresearch.bsky.social) on her recent induction into the @pennmedicine.bsky.social Academy of Master Clinicians! Learn more about Dr. Mascarenhas & her work here➡️ tinyurl.com/2kcuyzjs #PennMedicineAOMC

See the five CHOP Research science stories that engaged you – our community of patient families, colleagues & collaborators – the most this year in our annual end-of-year Cornerstone roundup: ms.spr.ly/63322tar6y

#ICYMI: Registration is now open for Cores Day on Thursday, September 11th!🥳🎉 @pennmedicine.bsky.social @chopresearch.bsky.social @PennVet ‪@wistar.org -Free registration➡️ tinyurl.com/3bu5pjfd -Event website➡️ tinyurl.com/yc83cmj4

Mark DeJesse, Senior Clinical Research Financial Analyst at CHOP, has participated as a Philly #Mummer since he was 5! As South Philly Vikings NYB treasurer, DeJesse continues a family legacy. Read our latest #CHOPOffCampus: ms.spr.ly/63320s560w

Our Cardiac Center is leading research to transform care for children with the most complex heart conditions. With newly awarded grants from Additional Ventures' Single Ventricle Research Fund, CHOP teams are advancing science in key areas like prenatal therapies and AI-powered diagnostics.

Cardiac Grants Propel Cutting-Edge Research to Transform Outcomes for Children with Severe Heart Conditions

The Cardiac Center at the Children’s Hospital of Philadelphia (CHOP) is leading pioneering research with grants aimed at improving outcomes for children with severe cardiac conditions. These efforts represent a comprehensive approach to advancing cardiac care from prenatal stages through childhood, potentially transforming treatment paradigms.

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🚨 NEW RESEARCH! ⚕️ 🩺 Kelchtermans et al. explore how being born early, air pollution, and genetic factors work together to increase asthma attacks in children. https://bit.ly/47DKjIg @chopresearch.bsky.social #PediatricHealth #AsthmaResearch

The impact of prematurity on pediatric asthma morbidity and indices with environmental pollution and genetic susceptibility - Communications Medicine

Kelchtermans et al. analyze interactions between prematurity, PM2.5 exposure and genetic susceptibility on asthma exacerbations in children. They find that combined effects produce outsized increases in exacerbation risk, underscoring the need for targeted interventions.

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New research out in @Structure_CP provides a structure-guided approach to predict MHC-I restriction of T cell receptors for public antigens ft. @sagargupta.bsky.social (@pennmedicine.bsky.social) & @SgourakisLab (@BB_UPenn) @chopresearch.bsky.social www.cell.com/structure/fu...

In a guest blog, the Center for Injury Research & Prevention's Associate Director Dr. Rachel Myers writes about 2 new studies on the value + long-term effectiveness of the CHOP Violence Intervention Program, a bridge from the hospital to the community: ms.spr.ly/63321spgQT

We're inspired by the student trainees in the Center for Autism Research's STAR program, who signed off from their summers at @childrensphila.bsky.social by proposing unique potential research projects on autism spectrum disorder! Learn more about STAR: www.research.chop.edu/services/stu...

#ICYMI: Registration is now open for Cores Day on Thursday, September 11th!🥳🎉 @pennmedicine.bsky.social @chopresearch.bsky.social @PennVet @wistar.org -Free registration➡️ tinyurl.com/3bu5pjfd -Event website➡️ tinyurl.com/yc83cmj4

In a new Snapshot Science, learn about CHOP research published in the journal Blood that describes the recovery role of the cytokine tumor necrosis factor alpha (TNFα) for anemia of inflammation. ms.spr.ly/63329sJxiU

In the journal Pediatrics, CHOP & Penn researchers identify & describe the potential factors that may contribute to eligible infants receiving, or not receiving, nirsevimab, a vaccine to prevent #RSV. ms.spr.ly/63325syk0W

Researcher in CHOP's Bioengineering & Biomaterials Lab are evaluating different cartilage cell types to improve the current standard of care for #laryngotracheal reconstruction. Learn more: ms.spr.ly/63325sEDYl

👏 Congrats to CHOP's Executive Vice President & CSO Dr. Susan Furth on receiving the 2025 Corporate Leadership Award from the Philadelphia Business Journal! Learn more about Dr. Furth: ms.spr.ly/63323sEDcl

In our latest #CHOPOffCampus blog, Ray Goodridge, Director of Clinical Trials Financial Management at CHOP Research, shares the lore behind his passion for race cars and need for speed: ms.spr.ly/63325sEDi5

😎 Meet the 2025 cohort of the Injury Science Research Experiences for Undergraduates (REU) program, a 10-week undergrad internship ft. unique hands-on research experience & mentoring: http://ms.spr.ly/63326S7DGk

Researchers at CHOP and St. Jude Research find genetic ancestry influences how gene mutations impact cancer prognosis in patients with T-ALL. The study is the first to explore the impact of genetic ancestry on tumor genomics in T-ALL. Learn more: http://ms.spr.ly/63321SL0lN.

Modeling the HLH immune synapse ft. @AFKamenetskii, Hannah Klinghoffer, @varghese_jemy, @DangitVinh, Jeremy Morrissette, @CarolineDiorio, @canna_lab (@chopresearch.bsky.social), @JoeFraietta (@PennMicro) & @JanKarlBurkhar1 (@PennNSG) ashpublications.org/blood/articl...

In our latest #OffCampus feature, Dr. Valentina Graci, leader of the Sled Lab for Automotive Safety and Rehabilitation Biomechanic, shares how she resets after life in the lab by volunteering as a scuba diver at a local aquarium. Read the full story now: http://ms.spr.ly/63327SxJKX

With funding from the Gates Foundation, CHOP's Infectious Diseases Chief Dr. Audrey Odom John + team are advancing the development of a 'malaria breathalyzer' to detect the malaria-causing parasite in asymptomatic patients & reduce transmission. Learn more: http://ms.spr.ly/63325SxyBS

In a new Cornerstone blog, read about studies from CHOP's Dr. Bev Davidson & team highlighting how several AAV capsid variants could improve the precision of gene therapy for neurodegenerative disorders: http://ms.spr.ly/63328SWf56

.@kiranmusunuru.bsky.social (@penngenetics.bsky.social/ @PennCardiology), @ahrensnicklas.bsky.social (@chopresearch.bsky.social) & colleagues raced against time to deliver a life-saving, 1st-ever personalized gene editing therapy for a 9-month-old patient with CPS1 deficiency tinyurl.com/3ncxd5ex

Congratulations to the 2025 winners of our Research Excellence at CHOP (RE@CH) Award: Katelynn Stanley (Genetics), Jamillah Millner (Injury Research), & Lauren Mitteer (Endo) for their valuable contributions as clinical research staff! http://ms.spr.ly/63326SiLnK