This malaria study has relevance to other high-antigen settings: doi.org/10.1172/JCI2... @prasannaj77.bsky.social & team @stanfordmedicine.bsky.social found children with high Tr1 frequencies were protected from symptomatic malaria despite parasitemia but also experienced delayed parasite clearance

Antigen-specific type 1 regulatory T cell responses shape immunity and disease tolerance in human malaria: doi.org/10.1172/JCI2... Leonie Brockmann comments on Nideffer et al. doi.org/10.1172/JCI2... @prasannaj77.bsky.social

Publications Alert- Malaria remains one of our oldest and most persistent adversaries — responsible for over 600,000 deaths annually, the vast majority in young children in sub-Saharan Africa. Despite remarkable progress, we still don't fully understand how the immune system learns how to protect

Excited to share the amazing PhD dissertation work of Jason Nideffer, who was mentored by Maria Grazia Roncarolo and myself. By following Ugandan children over time, Jason was able to track individual T-cell clones during and after malaria infections.

Christiana Fogg@cnfogg.bsky.social · last yr.

On #WorldMalariaDay, check out this brand new study on human T cell memory responses to #malaria from the lab of Pras Jagannathan at Stanford! 🦟🩸 www.science.org/doi/10.1126/...