GLP-1s Provide Benefit in HF Patients: SOUL Subanalysis

GLP-1s Provide Benefit in HF Patients: SOUL Subanalysis

GLP-1s Provide Benefit in HF Patients: SOUL Subanalysis cmacahilig@crf.org Fri, 02/06/2026 - 16:50 L.A. McKeown Those with preserved EF seemed to get more protection against HF events/CV death than those with reduced or unknown EF.

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Adding digitoxin to contemporary GDMT improves clinical outcomes in patients who have HFrEF, according to results from the DIGIT-HF trial. Read more here: #ESCCongress2025 www.tctmd.com/news/digitox...

Digitoxin Cuts Risk in Well-Treated HFrEF Patients: DIGIT-HF

(UPDATED) The effect size was modest, but the glycoside improved clinical outcomes when added to GDMT.

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Starting SGLT2 Inhibitors in the Hospital for Acute HF Gains Support

Starting SGLT2 Inhibitors in the Hospital for Acute HF Gains Support

Starting SGLT2 Inhibitors in the Hospital for Acute HF Gains Support cmacahilig@crf.org Sat, 08/30/2025 - 09:08 Todd Neale DAPA ACT HF – TIMI 68 missed its primary endpoint, but experts say the totality of the evidence backs early use of the drugs.

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#ESCGuidelines on #Myocarditis & #Pericarditis🫀 📍umbrella term: Inflammatory Myopericardial Syndrome used until diagnosis is clarified 📍Emphasizes use of #whyCMR 📍Clear recommendation for #EMB 📍Genetic & inherited CMPs highlighted🧬 🔗: doi.org/10.1093/eurhea… #ESCCongress @escardio.bsky.social

The Continuum of Prevention and Heart Failure in Cardiovascular Medicine: A Joint Scientific Statement from the Heart Failure Society of America and The American Society for Preventive Cardiology onlinejcf.com/article/S107... @drmarthagulati.bsky.social @dranulala.bsky.social @jcardfail.bsky.social

Atrial cardiomyopathy: From healthy atria to atrial failure. A clinical consensus statement of the #HFA of the ESC @escardio.bsky.social onlinelibrary.wiley.com/doi/10.1002/... @vietheartpa.bsky.social @anastasiasmihaili.bsky.social @cardioobdoc.bsky.social @erinmichos.bsky.social

Cardiologists More Often Send Higher-Risk Patients for CAC Scans vs Generalists

Cardiologists More Often Send Higher-Risk Patients for CAC Scans vs Generalists

Cardiologists More Often Send Higher-Risk Patients for CAC Scans vs Generalists cmacahilig@crf.org Tue, 07/29/2025 - 16:42 Yael L. Maxwell The decade-long, single-healthcare-system study gives insights into how physicians are using CAC tests and in which patients.

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Large #MetaAnalysis finds no significant difference in systolic or diastolic #BloodPressure between firstborns and later-borns. #BirthOrder may not affect blood pressure levels after all. #Epidemiology #PublicHealth www.sciencedirect.com/org/science/...

Unraveling the link between birth order and blood pressure: insights from a comprehensive systematic review and meta-analysis

The objective of the present systematic review was to incorporate previous studies investigating the association of birth order with the risk of systo…

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Conduction system pacing: promoting the physiology to prevent HF Background and Clinical perspectives of HBP and LBBP area in HF link.springer.com/article/10.1... #HF #CardioSky #CardioEd @cardioobdoc.bsky.social @drrajivsankar.bsky.social @annakatebarton.bsky.social @vietheartpa.bsky.social

Financial Toxicity: An Overlooked Driver of #HeartFailure Risk in the USA www.emjreviews.com/cardiology/a... #EMJCardiology @cardioobdoc.bsky.social @erinmichos.bsky.social @joyywu.bsky.social @anastasiasmihaili.bsky.social @vietheartpa.bsky.social

Financial Toxicity: An Overlooked Driver of Heart Failure Risk in the USA

Heart failure is responsible not only for high morbidity and mortality, but also for significant out-of-pocket expenses for patients...

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The invisible costs of heart failure: a societal toll academic.oup.com/eurheartj/ad... @escardio.bsky.social @cardioobdoc.bsky.social @shelleyzieroth.bsky.social @erinmichos.bsky.social @drmarthagulati.bsky.social

The impact of federal actions on academic medicine and the U.S. health care system www.aamc.org/about-us/aam... @cardioobdoc.bsky.social @arghavansallesmd.medsky.social @erinmichos.bsky.social @drmarthagulati.bsky.social

🚀 Want to stay updated with the latest from #EHJCVI and #EHJIMP? 📷 Follow our amazing Social Media Editors! 📷 @EHJCVIEiC & @EHJIMPEiC, our Editors-in-Chief bringing the latest to your feed! @escardio.bsky.social @jgrapsa.bsky.social @hancardiomd.bsky.social

Long-term trials of colchicine for secondary prevention of vascular events: a meta-analysis #Colchicine significantly reduced #MACE in patients with vascular disease: pooled HR 0.75 (95% CI 0.56–0.93) across 6 RCTs (n=21,800). #CardioSky @escardio.bsky.social

This damage will be irreparable. www.thetransmitter.org/funding/prop...

Proposed NIH budget cut threatens ‘massive destruction of American science’

A leaked draft of a Trump administration proposal includes an approximately 40 percent cut to the National Institutes of Health’s budget and a major reorganization of its 27 institutes and centers.

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Evolution of Critical Care Cardiology: An Update on Structure, Care Delivery, Training, and Research Paradigms: A Scientific Statement From the American Heart Association #CCU #CICU #JACC #CardioSky @jaccjournals.bsky.social @americanheart.bsky.social @accintouch.bsky.social

Phase 3 trial of PO #Orforglipron ; lowering A1C by an average of 1.3% to 1.6% across doses Once-daily oral pill reduced weight by an average 16.0 lbs (7.9%) at the highest dose in a key S’ endpoint @tctmd.bsky.social @mmamas1973.bsky.social @shelleyzieroth.bsky.social @drmarthagulati.bsky.social

Gaps and Knowledge in the Contemporary Management of Acute Right Ventricular Failure www.ahajournals.org/doi/10.1161/... @ahascience.bsky.social #RVFailure #HeartFailure #CardioEd @cardioobdoc.bsky.social @shelleyzieroth.bsky.social @mmamas1973.bsky.social @mirvz.bsky.social

#Cancer and #CVD are intertwined, with inflammation and a dysregulated immune system being common contributors Shared Mechanisms in Cancer and #CVD : #S100A8/9 and the #NLRP3 #Inflammasome #CardioSky #OncoSky @cardioobdoc.bsky.social @novitham.bsky.social @pnatarajanmd.bsky.social

Clinical and plasma proteomic characterization of heart failure with supranormal left ventricular ejection fraction: An emerging entity of heart failure #EJHF @escardio.bsky.social #CardioSky @shelleyzieroth.bsky.social @jimjanuzzi.bsky.social @drmarthagulati.bsky.social @cardioobdoc.bsky.social

#Aldosterone-targeted therapies: early implementation in resistant #HTN and #CKD Reflecting on the fundamentals and exploring future directions academic.oup.com/eurheartj/ad... #CardioSky @escardio.bsky.social #EHJ @cardioobdoc.bsky.social @shelleyzieroth.bsky.social @drrajivsankar.bsky.social

#Finerenone, glycaemic status, and heart failure with mildly reduced or preserved ejection fraction: A prespecified analysis of the #FINEARTS-HF trial onlinelibrary.wiley.com/doi/full/10.... @escardio.bsky.social #CardioSky @

#Aldosterone-targeted therapies: early implementation in resistant #HTN and #CKD Reflecting on the fundamentals and exploring future directions academic.oup.com/eurheartj/ad... #CardioSky @escardio.bsky.social #EHJ @cardioobdoc.bsky.social @shelleyzieroth.bsky.social @drrajivsankar.bsky.social

Dr. Shirlee Song presents sex differences in #stroke #WIHD25 🧠 many sex disparities in the Tx of stroke:⬆️ disability b/c less tx 🧠 fewer studies in 💃🏻 🧠 cerebral ischemia may not be same in women🆚 men 🧠 women have more stable plaques & ⬆️ Sx risk @womensheart.bsky.social @smidtheart.bsky.social

This State-of-the-Art Review addresses the current understanding on the pathophysiological link between #CVD and #CKD, clinical implications and challenges academic.oup.com/eurheartj/ad... #CardioSky @escardio.bsky.social @cardioobdoc.bsky.social @hvanspall.bsky.social @novitham.bsky.social

New Dual Endothelin Receptor Antagonist Aprocitentan in Hypertension: A Systematic Review and Meta-Analysis www.sciencedirect.com/science/arti... #Aprocitentan #CardioSky @anastasiasmihaili.bsky.social @mmamas1973.bsky.social @cardioobdoc.bsky.social @shelleyzieroth.bsky.social

New Dual Endothelin Receptor Antagonist Aprocitentan in Hypertension: A Systematic Review and Meta-Analysis

Hypertension is one of the most common disorders encountered, yet pharmacotherapy for resistant hypertension has limited effective options. Aprocitent…

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Lower extremity lymphatic flow is associated with diuretic response in acute heart failure In 65 AHF patients, lymphatic flow (via ICG lymphangiography) predicted diuretic response. #AHF #CardioSky #Lymphatics #AHF @shelleyzieroth.bsky.social @escardio.bsky.social @drrajivsankar.bsky.social

FDA Drops REMS Requirement for Antihypertensive Aprocitentan

FDA Drops REMS Requirement for Antihypertensive Aprocitentan

FDA Drops REMS Requirement for Antihypertensive Aprocitentan sciprian@crf.org Wed, 04/09/2025 - 16:46 Michael O'Riordan The drug was approved last year for patients with hypertension currently not controlled on other BP-lowering agents.

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Efficacy, Safety and Mechanistic Impact of a #HeartFailure Guideline-Directed Medical Therapy Clinic #JACCHF #CardioSky #GDMT www.jacc.org/doi/full/10.... @jimjanuzzi.bsky.social @jaccjournals.bsky.social @drmarthagulati.bsky.social @cardioobdoc.bsky.social @shelleyzieroth.bsky.social

Easy and potentially very useful!

Henry Han @hancardiomd.bsky.social · last yr.

Prognostic value of left atrioventricular coupling index in heart failure In 478 HF patients (LVEF <50%), higher #LACI (≥30.9%) was linked to worse outcomes. academic.oup.com/ehjcimaging/... @escardio.bsky.social @cardioobdoc.bsky.social @vassv.bsky.social @shelleyzieroth.bsky.social