Dominique Holtappels
@dholtappels.bsky.social
Assistant Professor @ Cornell AgriTech Plant Pathology in Controlled Environment Agriculture Studying the ecology and evolution of plant diseases Phages, cats, coffee and scicomm
So enjoyable to work with both @bkoskella.bsky.social & @dholtappels.bsky.social on this project! Which started as a brilliant idea from Britt at the Wiko, and has continued remotely since (ft also a lovely trip to Berkeley!) ☺️ yay for team science!
COBRA improves the completeness and contiguity of viral genomes assembled from metagenomes www.nature.com/articles/s41... 🧬🖥️ github.com/linxingchen/...
COBRA improves the completeness and contiguity of viral genomes assembled from metagenomes - Nature Microbiology
Contig overlap-based reassembly enables the generation of accurate and high-quality viral genomes from assembled metagenomes.
nature.com
Revised preprint: Phage predation is a biomarker for disease severity and shapes pathogen genetic diversity in cholera patients. To support major conclusions, we repeated key analyses using qPCR instead of metagenomics to quantify phage ICP1 and V. cholerae www.biorxiv.org/content/10.1...
Fabulous work by my colleagues - Stick'em with the pointy end ... UNLESS ...??? www.nature.com/articles/s41...
The evolution of short- and long-range weapons for bacterial competition - Nature Ecology & Evolutio...
An agent-based model suggests that bacteria use direct-contact systems for inhibiting competitors when the attacking strain is outnumbered, and long-range diffusion systems when the attacker is common...
nature.com
Our paper looking into the phenomenon of domain mosaicism in phages is now out in Nature Communications. Work led by Bogna Smug together with Krzysztof Szczepaniak, @epcrocha.bsky.social and @staszekdh.bsky.social. See a short thread. 1/7 www.nature.com/articles/s41...
Ongoing shuffling of protein fragments diversifies core viral functions linked to interactions with ...
Proteins are composed of distinct functional domains, each serving a specific role. Here, Smug et al. show that phages are able to shuffle fragments of their proteins and this predominantly occurs in ...
nature.com
#Microsky #Phagesky Interesting "primer for evolutionary biologists interested in studying social evolution in viruses" 👇 onlinelibrary.wiley.com/doi/10.1111/...
Open questions in the social lives of viruses
Social interactions among viruses are diverse and pervasive, with the potential to affect every stage of the viral lifecycle. Here, we explore some of the challenges and opportunities that these inte....
onlinelibrary.wiley.com
