Very excited to share our work on a novel itaconate transporter in P. aeruignosa! A brilliant team effort by the @gavinhthomas.bsky.social lab. 🎉🎉🎉

Gavin Thomas (he/him)@gavinhthomas.bsky.social · last yr.

Delighted with our new paper on a novel itaconate transporter in the human pathogen Pseudomonas aeruginosa, led by Javeria and Reyme. @ybri-uoy.bsky.social @javeriamehboob.bsky.social @bethkw.bsky.social A duplicated transporter on its way to itaconate selectivity portlandpress.com/biochemj/art...

New from the lab of @gavinhthomas.bsky.social : TRAP transporters are always fun and Pseudomonas is a super cool bug. And well done Javeria (who may not be over here yet?)!! www.biorxiv.org/content/10.1...

Itaconate utilisation by the human pathogen Pseudomonas aeruginosa requires uptake via the IctPQM TRAP transporter

Pseudomonas aeruginosa PA01 is one of the major causes of disease persistence and mortality in patients with lung pathologies, relying on various host metabolites as carbon and energy sources for grow...

biorxiv.org