Tessera

Simon Aubé

@simonaube.bsky.social

PhD student in the Landry lab at Université Laval. Evolution and hockey analytics enthusiast. He/him

A new review on #evolution is online! Pavithra Venkataraman and Christian Landry @christianlandry.bsky.social discuss a conceptual framework for the joint influence of coding and regulatory mutations in shaping fitness and impacting molecular #evolution. -> link.springer.com/article/10.1...

Molecular evolution in light of regulatory-coding epistasis - EMBO Reports

Predicting the fitness effects of mutations is central to understanding molecular evolution and interpreting genome sequence data. Such predictions remain challenging due to the inter-dependent roles ...

link.springer.com

Soham Dibyachintan @sohamdibyachintan.bsky.social · last yr.

How does cryptic genetic variation influence the long-term fate of gene duplicates (paralogs)? Our new study addresses this question by dissecting the evolutionary potential of redundant myosin paralogs in yeast nature.com/articles/s41... (1/12)

Cryptic genetic variation shapes the fate of gene duplicates in a protein interaction network - Nature Communications

Over time, paralogous genes accumulate changes in their sequences that do not affect their function, which is called cryptic variation. Using paralogous myosins, this study shows how cryptic variation...

nature.com