New Article: "Imputation integrates single-cell and spatial gene expression data to resolve transcriptional networks in barley shoot meristem development" rdcu.be/eYiMF With Research Briefing rdcu.be/eYiM7
It's finally out!... Using single-cell and spatial transcriptome data, and data imputation, we created BARVISTA, a website able to perform almost genome-wide information on gene expression profiles at single-cell resolution in barley spikes! www.nature.com/articles/s41...
Imputation integrates single-cell and spatial gene expression data to resolve transcriptional networks in barley shoot meristem development - Nature Plants
Spatially resolved gene expression during barley development was done by integrating an scRNA-seq dataset from cells with unknown position with spatial transcriptomics. This dataset is publicly availa...
nature.com
Happy to share our recent thoughts on how grasses form and pattern stomata doi.org/10.1016/j.pb... 🌾From fate establishment, through within-file patterning to dumbbell formation🌾 Congrats to @lbmountain.bsky.social on getting two publications out in a single day - a first for the lab!
A wonderful collaboration with our colleagues from Düsseldorf within the @cerealcell.bsky.social consortium. @isaiavardanega.bsky.social @simonrdg.bsky.social Jan Maika. Thanks to the sequencing facilities at Uni Heidelberg and Uni Bern, and past and present team members for this "tour de force"
I’m proud to present the main work from my postdoc, 3+ years in making from scratch, my ultimate #MimulusPropaganda up till now: The Moment That Symmetry Breaks. #plantscience #development #imaging #microscopy 🧪🌸🔬 w. Captain Yaowu & @biancatash.bsky.social www.biorxiv.org/content/10.1...
From Tip to Grain: Sculpting Barley Inflorescence Through the Regulation of Meristem Activity thenode.biologists.com/from-tip-to-...
From Tip to Grain: Sculpting Barley Inflorescence Through the Regulation of Meristem Activity - the Node
Written by Isaia Vardanega Behind the Paper Story of “CLAVATA signalling shapes barley inflorescence by controlling activity and determinacy of shoot
thenode.biologists.com
Meristems shape plant architectures, and grasses generate a complex array of them. To characterise barley vegetative SAMs and spike development, we used single cell and spatial transcriptome data and integrated them in a new database, BARVISTA. A click on a cell now..... tinyurl.com/38c3mf5d
#PlantScience Research Weekly: May 23, 2025 plantae.org/plant-scienc... Lost in translation; How to eat an idea; RNA editing in mitochondria; Non-destructive ubiquitin tagging by COP1; When CLV walked in fields of gold (1/2)
I am thrilled to share our work on integrating single-cell and spatial transcriptomics. Here, we assign a spatial position to protoplasts by gene expression imputation, allowing us to dissect regulatory networks during meristem and organ determination in barley. www.biorxiv.org/content/10.1...
Imputation integrates single-cell and spatial gene expression data to resolve transcriptional networks in barley shoot meristem development
Grass inflorescences are composite structures, featuring complex sets of meristems as stem cell niches that are initiated in a repetitive manner. Meristems differ in identity and longevity, generate b...
biorxiv.org
Excited to see our work finally out! 🌾🏴☠️ We show how HvCLV1 and HvFCP1 shape barley inflorescence using innovative techniques and some cool microscopy. Huge thanks to everyone involved in this study! t.co/ofButB3fRo
https://www.nature.com/articles/s41467-025-59330-z
t.co
PHOTOPERIOD 1 enhances stress resistance and energy metabolism to promote spike fertility in barley under high ambient temperatures (Tianyu Lan, Agatha Walla, Kumsal Ecem Çolpan Karışan, et. al.) academic.oup.com/plphys/advan... #PlantScience
academic.oup.com