New in Nature Mental Health: our SMART-D precision medicine trial tested biomarkers to guide sertraline vs bupropion in MDD (rdcu.be/fsf2V). Biomarker-positive patients had better symptom trajectories than those without biomarkers (71.4% vs. 42.9% response rates). #Depression #PrecisionPsychiatry

20 years after the first Probabilistic Reward Task (PRT) paper, this review highlights a cross-species measure of reward learning—linking anhedonia, depression risk, neural circuitry, and treatment-relevant mechanisms. rdcu.be/fsf29 #Anhedonia #Depression

1/2: Dear colleagues: Due to a flurry of applications received on June 15, we are extending the application deadline to June 22 for two open-rank faculty positions within the Noel Drury, M.D. Institute for Translational Depression Discoveries at UC Irvine.

1/7: On June 9, we marked a major milestone in mental health research with the formal launch of the Noel Drury, M.D. Institute for Translational Depression Discoveries at the University of California, Irvine—the first institute in the nation to formally unite …

1/6: Two faculty positions at the Noel Drury, M.D. Institute for Translational Depression Discoveries Delighted to announce that we have two faculty openings for the Noel Drury, M.D. Institute for Translational Depression Discoveries at UC Irvine. The submission deadline is June 15, 2026.

Excited to share this publication from my work as a research assistant in the lab of @diegopizzagalli.bsky.social . Such an honor to train under this all-star team! www.nature.com/articles/s42...

Identification of conserved frontal neurophysiological markers of cognitive flexibility in humans and rats - Communications Biology

Integration of a probabilistic reversal learning task aligned between humans and rodents demonstrates concordant behavioral, computational, and neurophysiological measures of cognitive flexibility bet...

nature.com

1/3: in light of recent developments across the US academic landscape, which might have presented challenges to colleagues, we decided to extend the submission deadline for our three faculty openings focused on depression until May 14, 2025.

1/2: Important new findings by Peter Zhukovsky, a former postdoc in the lab and now faculty at CAMH, who identified a neural (rsfMRI) marker that predicted SSRI treatment response.

🧪🧠 1/2: Final reminder that the deadline for the faculty cluster hire (3 faculty positions) within the newly established Noel Drury, M.D. Institute for Translational Depression Discoveries at UC Irvine is April 9, 2025.

beautiful and impactful review paper!

Tallie Z Baram@talliezee.bsky.social · last yr.

JUST dropped! Neuron review with Matt Birnie on the evolving neurobiology of early-life stress. Where is our field? what are our challenges? where and how do we move forward? www.cell.com/neuron/fullt... would love your thoughts🧠🧪 @cp-trendsneuro.bsky.social @cate-cholamine.bsky.social