Glycan Atlassing is online at @natnano.nature.com! Thanks to everyone involved, especially to @dijo-mj.bsky.social and @nazlicanyurekli.bsky.social who spearheaded the work. Read the paper here: dlvr.it/TSXNDb #Glycotime

Glycan atlassing enables functional tracing of cell state - Nature Nanotechnology

Multiplexed super-resolution microscopy of DNA-barcoded lectins and metabolically incorporated unnatural sugars quantitatively links the nanoscale spatial relationships of glycocalyx organization and ...

dlvr.it

Nazlican Yürekli@nazlicanyurekli.bsky.social · 3mo ago

Thrilled to announce that our paper on Glycan Atlassing is officially published in Nature Nanotechnology!🧬🍭 We developed "Glycan Atlassing," a method to map the glycocaly at nanometer resolution. This allows us to trace cellular states and opens new avenues for diagnostics and therapy..

NEW PREPRINT: Spatial mapping of cell-surface protein glycosylation at molecular resolution 🍭🍬🔬 For the first time, we can analyze the spatial architecture of the cell-surface glycoproteome at single-protein and single-sugar resolution. #glycotime www.biorxiv.org/content/10.1...

Spatial mapping of cell-surface protein glycosylation at molecular resolution

Cell-surface protein glycosylation is a fundamental post-translational modification that plays a crucial role in membrane protein function and cellular behavior. However, elucidating the molecular spa...

biorxiv.org

Attended #SMLMS2025 last week in Bonn, Germany. Many thanks to the organizers @uendesfelder.bsky.social @heilemannlab.bsky.social and Prof. Kubitscheck for introducing #youngSMLMS. That was really mindful of the young researchers including me:). Had a great time in Bonn discussing science.

Very happy to see this one out - the first molecular-resolution imaging of glycocalyx components in their native environment! Great collaboration with @jungmannlab.bsky.social - congrats to first authors @karimalmahayni.bsky.social and @lumasullo.bsky.social and to the whole team!

Nature Nanotechnology@natnano.nature.com · last yr.

New paper online: Ångström-resolution imaging of cell-surface glycans. The molecular organization of sugars in the native #glycocalyx has been resolved at 9 ångström using bioorthogonal metabolic labeling and #superresolution imaging of DNA barcodes. #Glycotime www.nature.com/articles/s41...

GLYCAN ATLASSING: NANOSCALE ANALYSIS OF GLYCOCALYX ARCHITECTURE ENABLES FUNCTIONAL TRACING OF CELL STATE 🍭🔬🧬 Don’t judge a book by its cover - judge a cell by its cover! We can now trace how cell state is encoded in glycocalyx state. #glycotime #microscopy www.biorxiv.org/content/10.1...