🎉 New PubMed-indexed article in *Diseases & Research*! “Krüppel-like Factor 2 (KLF2) Regulates Autophagy, Mitophagy, Mitochondrial Health, and Function During Foam Cell Formation” 📖 Read: dr.clintile.com/en/article/d... #PubMed #Autophagy #Mitophagy
Diseases & Research
@disres.bsky.social
D&R, an international academic journal, aims to advance research in medicine and pharmacy with human diseases. Link: https://dr.clintile.com/
📢 Call for Papers Autoimmunity: From Mechanisms to Clinical Practice Guest Editor: Prof. Yehuda Shoenfeld 🔬 Autoimmunity, biomarkers, immune regulation & therapies ✅ APC waived 📅 30 Oct 2026 dr.clintile.com/en/topic?id=... #Autoimmunity #Immunology
We are pleased to welcome Prof. Leonora Balaj, PhD, Assistant Professor of Neurosurgery at Harvard Medical School, as a member of the Editorial Board of Diseases & Research. Learn more: dr.clintile.com/editorBord #EditorialBoard #HarvardMedicalSchool #OpenAccess #BiomedicalResearch
New review by Prof. Anil Parwani's group. “Applications of Artificial Intelligence for Pathological Diagnosis of Bladder Cancer” Read full text: dr.clintile.com/article/doi/... #AI #Pathology #BladderCancer #DigitalPathology
🫀 Coronary artery tortuosity was found in 85.1% of patients with Takotsubo cardiomyopathy. CAT severity was not linked to troponin or EF recovery, but may represent a vascular phenotype in Takotsubo syndrome. dr.clintile.com/article/doi/... #Takotsubo #Cardiology #HeartFailure #Cardiomyopathy
Can radiotherapy be safely delivered in a painful PHN field? A new case report describes successful superficial radiotherapy for cutaneous squamous cell carcinoma in a symptomatic PHN dermatome using a stand-off technique. dr.clintile.com/article/doi/... #Radiotherapy #SkinCancer #cSCC #PHN
Call for papers: Cerebral Aneurysm From AI & imaging to endovascular and microsurgical advances—seeking cutting-edge research on aneurysm biology, risk, and management. FREE APC!!! Guest Editor: Dr. Brandon Lucke-Wold dr.clintile.com/en/topic?id=... #Neurosurgery #Stroke #CerebralAneurysm
Call for papers: Lung Disease From inflammation & immune responses to nanomedicine and advanced drug delivery—seeking cutting-edge studies in respiratory research. Guest editor: Prof. Kamal Dua FREE APC!!! dr.clintile.com/en/topic?id=... #LungDisease #RespiratoryResearch #Nanomedicine
KLF2 drives stem cell osteogenesis via autophagy and mitochondrial control. Ellagic acid promotes osteogenic differentiation in DPSCs, enhanced by KLF2 through autophagy/mitophagy and bioenergetics. Now on PubMed 👇 pubmed.ncbi.nlm.nih.gov/42022281/ #StemCells #RegenerativeMedicine #Autophagy
Dental pulp stem cell secretome suppresses glioblastoma progression by reducing inflammation, ROS, and metabolic activity, leading to G1 cell cycle arrest via MAPK–AKT pathway inhibition. Suggests a potential cell-free adjuvant strategy for GBM. pmc.ncbi.nlm.nih.gov/articles/PMC...
ADAMTS proteases regulate cancer metastasis by remodeling extracellular matrix and modulating signaling pathways (TGFβ, Wnt/β-catenin, EGFR/ERK), influencing tumor progression in a context-dependent manner. They are therapeutic targets in oncology. DOI: pmc.ncbi.nlm.nih.gov/articles/PMC...
A single-layer paper-based assay for 3D cell migration. Cells migrate from paper → plate, quantified by MTT & counting. 📊 MDA-MB-231: 15.4× 📊 MCF7: 3.8× 📊 MCF10A: none Consistent with wound healing. 🔗 dr.clintile.com/article/doi/... #CellMigration #3Dculture #CancerResearch
AI is reshaping histopathology. Prof. Pier Paolo Piccaluga’s team reviews how AI enables cancer detection, mutation prediction, and multi-omics integration—while addressing challenges in validation and standardization. dr.clintile.com/article/doi/... #AI #DigitalPathology #PrecisionMedicine
We are pleased to welcome Prof. Yehuda Shoenfeld to the Editorial Board of Diseases & Research. A globally recognized leader in autoimmunity, his expertise will support the journal’s growth in immunology. Learn more: dr.clintile.com/editorBord #Autoimmunity #Immunology #AcademicPublishing
New issue out now 🚀 Diseases & Research Vol.6 No.1 features 7 articles: Stem cells • Parkinson’s disease • Colon cancer care • Traditional medicine • HBV immunotherapy • Venous disease • Case report 🔗 dr.clintile.com #MedicalResearch #OpenAccess #Immunotherapy
ICIs in chronic hepatitis B—cure or just faster clearance? A new Commentary featuring Prof. Fengmin Lu (Peking University) suggests ICIs may accelerate HBsAg loss without improving overall cure rates. 🔗 dr.clintile.com/article/doi/... #HepatitisB #HBV #Immunotherapy #PD1 #LiverDisease #HCC
Can radiotherapy boost immunotherapy in rare biliary cancer? 🧬 85F, chemo-refractory ➡️ SBRT + PD-1 inhibitor + GM-CSF ➡️ Complete metabolic response ➡️ PFS 25 months 💡 Possible abscopal effect Read: dr.clintile.com/article/doi/... #Oncology #Immunotherapy
Better ideas drive clinical innovation. 📊 53 ideas → 47% became protocols 🔑 What works? • Strong support • GCP • Training • Peer review • Workshops • Collaboration • Funding & engagement Read more: dr.clintile.com/article/doi/... #ClinicalResearch #Oncology
Radical cystectomy outcomes can be improved with the right approach. The GRACE-M project highlights how a multidisciplinary pathway—focusing on frailty & nutrition—can significantly reduce major complications at 90 days. dr.clintile.com/article/doi/... #Urology #BladderCancer #ERAS #Surgery
ICIs transformed oncology—but ICIs-myocarditis is rare & fatal. This review challenges the “troponin-centric” model and proposes a dynamic risk approach. 🔗 dr.clintile.com/article/doi/... #CardioOncology #Immunotherapy #Myocarditis #Biomarkers
🧠 Can natural phytochemicals help target α-synuclein in Parkinson’s disease? This in silico study highlights promising neuroprotective compounds using molecular docking & MD simulations. 📖 dr.clintile.com/article/doi/... #Parkinsons #DrugDiscovery #Bioinformatics
🧠 Stem cell therapies are opening new possibilities for neurological disorders like AD, PD, stroke & MS. From neuroregeneration to precision medicine, this review highlights key advances—and remaining challenges. 📖 dr.clintile.com/article/doi/... #StemCells #Neuroscience #RegenerativeMedicine
🚨 KLF2 helps protect against foam cell formation by restoring autophagy, mitophagy & mitochondrial function while reducing glycolysis. From Hiranmoy Das group. 💡 A promising target for atherosclerosis 🔗 dr.clintile.com/article/doi/... #Atherosclerosis #KLF2 #Autophagy #Metabolism
Patient-centered care starts with listening. This scoping review highlights the global use of MYMOP to capture patient-reported outcomes, especially in musculoskeletal, psychological, and pain-related conditions—from Jacob Rosenberg’s group. dr.clintile.com/article/doi/... #PatientCentered #MYMOP
🧬 Doxorubicin remains a cornerstone in breast cancer treatment. This review highlights its anticancer mechanisms and future directions. 📖 dr.clintile.com/article/doi/... PMID: 40530298 #BreastCancer #Oncology #CancerResearch
Are interferons friend or foe in colorectal cancer? They can enhance anti-tumor immunity—but also contribute to tumor progression and immune evasion. A true double-edged sword in CRC. Free read: dr.clintile.com/en/article/d... PMCID: PMC11220628 #ColorectalCancer #Immunology
📢 Submit your research in lung disease Innovative Drug Delivery and Therapeutic Strategies in Lung Diseases Focus: drug delivery, nanomedicine, inflammation, precision medicine 💡 APC FREE | 📅 Dec 31, 2026 🔗 dr.clintile.com/en/topic?id=... #RespiratoryMedicine #DrugDelivery
Omega-3 PUFAs are more than supplements — they may be key regulators of brain health across the lifespan • Neurodevelopment & cognition • ASD & ADHD potential • Gut-brain axis link • Precision nutrition future Read free: dr.clintile.com/article/doi/... #Neuroscience #BrainHealth #Omega3 #ADHD
ADAMTS Proteases: Their Multifaceted Role in the Regulation of Cancer Metastasis Review by Rachele Bacchetti et al. on their roles in tumour microenvironment & cancer progression. 📌 PMCID: PMC7616120 dr.clintile.com/article/doi/... #CancerResearch #TumourMicroenvironment #ECM #Metastasis
🧬 Doxorubicin remains a cornerstone in breast cancer treatment. This review highlights its anticancer mechanisms and future directions. 📖 dr.clintile.com/article/doi/... PMID: 40530298 #BreastCancer #Oncology #CancerResearch