A dual sensor regulates P-glycoproteins structural plasticity www.biorxiv.org/content/10.64898/2026.03.13.711505v1 #cryoEM

Great to see one of my PhD projects out on bioRxiv. We report "A dual sensor regulates P-glycoproteins structural plasticity." Congrats to Michael Kamel for doing the heavy lifting from @arnemoeller.bsky.social & Urbatsch Lab. doi.org/10.64898/202... #b3d #cryoEM

What an inspiring few days at the #WEHeraeusSeminar! Great science, lively discussions, and lots of fun with the amazing community of #cryoEM, #StructuralBiology & #Microscopy. Huge thanks to everyone!

Anika Baier@anikabaier.bsky.social · 11mo ago

Big thanks to @arnemoeller.bsky.social , @djanuliene.bsky.social, all speakers, and everyone who made the #WEHeraeusSeminar - Cryo-EM on the Move such an amazing event! It was a blast! #cryoEM #StructuralBiology #Microscopy

#STEM meets #cryoEM - Carsten Sachse @sachsegroup.bsky.social gave us a glimpse of just how far we might go 🚀🔬 #WEHeraeusSeminar #StructuralBiology #Microscopy @arnemoeller.bsky.social

Bringing colour to #cryo-EM - establishing methods for metal assignment in cryopreserved complexes! Fantastic talk by Bonnie Murphy! #WEHeraeusSeminar #StructuralBiology #Microscopy @arnemoeller.bsky.social @mpibp.bsky.social

Cristina Paulino @cpaulino.bsky.social, provocative as always - sparking thoughts on male contraception! #WEHeraeusSeminar #cryoEM #StructuralBiology #Microscopy @arnemoeller.bsky.social

Philipp Sebastian Erdmann @3p1l.bsky.social showed how SOLIST boosts cryo lift-out: more stability, more throughput! 🚀 #WEHeraeusSeminar #cryoEM #StructuralBiology #Microscopy @arnemoeller.bsky.social

Arjen Jacobi @cryotud.bsky.social presented novel cryo-EM specimen carriers, enabling time-resolved studies in a conceptually new way. Fantastic work! #WEHeraeusSeminar #cryoEM #StructuralBiology #Microscopy @arnemoeller.bsky.social

Sybodies and libraries: both have shelves full of things that stick 😀🧬📚 It’s always so fun listening to Markus Seeger @seegerlab.bsky.social! #WEHeraeusSeminar #cryoEM #StructuralBiology #Microscopy @arnemoeller.bsky.social

Henriette Autzen introduced novel polymers for detergent-free membrane protein extraction. #WEHeraeusSeminar #cryoEM #StructuralBiology #Microscopy @arnemoeller.bsky.social

Steven De Gieter shared his secret recipe for purifying a protein of interest out of the soup of molecules! 🍜 #WEHeraeusSeminar #cryoEM #StructuralBiology #Microscopy @arnemoeller.bsky.social

#MassSpec + #CryoEM = novel specimen preparation! Engaging talk by Tim Grant, addressing the tricky issues of sample dehydration, rehydration, and compaction. #WEHeraeusSeminar #cryoEM #StructuralBiology #Microscopy @arnemoeller.bsky.social

Filamentous phage vs. spaghetti - tough choice, but dinner wins 🍝😄 As always, a fantastic talk by Vicky @the-gold-lab.bsky.social! #WEHeraeusSeminar #cryoEM #StructuralBiology #Microscopy @arnemoeller.bsky.social

Mind-blowing presentation by Henning Stahlberg - exploring the structural basis of neurodegeneration and pushing the boundaries of #cryoEM! #WEHeraeusSeminar #StructuralBiology #Microscopy @arnemoeller.bsky.social

Fascinating talk by Phil Stansfeld @pstansfeld.bsky.social - a great reminder of how beautifully #cryoEM and MD simulations complement each other! 😃 #WEHeraeusSeminar #StructuralBiology #Microscopy @arnemoeller.bsky.social

A molecular atlas of the cell motility machinery - beautifully presented by Florian Schur @schurlab.bsky.social #WEHeraeusSeminar #cryoEM #StructuralBiology #Microscopy @arnemoeller.bsky.social

Fully confidential - typical #cryoEM reviewers😁 Becky @rebeccathompson.bsky.social, it was so nice meeting you again! And thanks to you & Thermo Fisher for covering the bar tab! 🍻😏 #WEHeraeusSeminar #cryoEM #StructuralBiology #Microscopy @arnemoeller.bsky.social

We all love colours, especially, when they can be generated automatically! Fantastic talk by Danielle Grotjahn @nanigrotjahn.bsky.social linking method development, structural biology and cell biology! #WEHeraeusSeminar #cryoEM #StructuralBiology #Microscopy @arnemoeller.bsky.social

From the early days at the “Laboratorium für Übermikroskopie” to today’s cutting-edge Cryo-FIB milling - Jürgen Plitzko showed us how far in situ structural biology has come, and where it’s heading! #WEHeraeusSeminar #cryoEM #StructuralBiology #Microscopy @arnemoeller.bsky.social

Wanda Kukulski reminded us how much there’s still to learn about apoptosis and how different results can look in vitro vs. in situ! #WEHeraeusSeminar #cryoEM #StructuralBiology #Microscopy @arnemoeller.bsky.social

#CryoEM on the move! Yesterday evening, Werner Kühlbrandt opened the WE-Heraeus Seminar with an inspiring journey from 2D crystallography to cutting-edge in situ tomography ❄️🧊🔬 #StructuralBiology #ScienceSeminar #Microscopy @arnemoeller.bsky.social

Deadline extended: Apply by June 30! Scientific organizers @arnemoeller.bsky.social #cryoEM

Dovile Januliene@djanuliene.bsky.social · last yr.

🚨 Last week to apply! Join the WE-Heraeus Seminar #CryoEM on the Move: New Applications and Challenges 🧊🔬 📅 Sept 14–17, 2025 | 📍 Bad Honnef, Germany ✅ No fee, full-board covered! 🔗 Apply now: indico.we-heraeus-stiftung.de/event/24/reg... #CryoEM #StructuralBiology #ScienceSeminar #Microscopy

🚨 Last week to apply! Join the WE-Heraeus Seminar #CryoEM on the Move: New Applications and Challenges 🧊🔬 📅 Sept 14–17, 2025 | 📍 Bad Honnef, Germany ✅ No fee, full-board covered! 🔗 Apply now: indico.we-heraeus-stiftung.de/event/24/reg... #CryoEM #StructuralBiology #ScienceSeminar #Microscopy

842. WE-Heraeus-Seminar: Cryo‐EM on the Move: New Applications and Challenges

With the resolution revolution, cryo-electron microscopy (cryo-EM) has unveiled its potential in structural biology. It has now become the dominant method for solving de novo structures of macromolecu...

indico.we-heraeus-stiftung.de

Arne Möller@arnemoeller.bsky.social · last yr.

Dear all, I am very excited about the upcoming 842 WE-Heraeus-Seminar #Cryo-EM on the Move. @djanuliene.bsky.social and I are looking forward to a great conference with many exciting speakers!

Dear all, I am very excited about the upcoming 842 WE-Heraeus-Seminar #Cryo-EM on the Move. @djanuliene.bsky.social and I are looking forward to a great conference with many exciting speakers!

Grateful for all involved in getting me here! @dfg.de @arnemoeller.bsky.social Off to new cryoEM adventures!

Lander Lab@landerlab.bsky.social · last yr.

Congrats to our postdoc Jan-Hannes Schaefer @jhschaef.bsky.social on being awarded a fellowship from the Walter Benjamin Program! Jan is collaborating with the Kelly lab here at Scripps Research @scripps.edu to understand how transthyretin forms amyloids that lead to heart disease.

Perfection.

Don‘t mix Jena with Vienna! Ute @hellmichgroup.bsky.social is revealing the mystery of allosteric nucleotide sensing in ABC transporters at #ABC2025

Arne @arnemoeller.bsky.social introducing the speakers of the morning session with a great reminder of why controls matter! Take away: Worms on the grid? Maybe your protein is not it! 🐛🤣

Annika Baier from @arnemoeller.bsky.social Lab is kicking off the afternoon session! You think you know your transporter? Not until you've seen it at least in a dozen different environments! 🥰 Maybe you can clarify a longstanding controversy along the way www.biorxiv.org/content/10.1...

The ABC transporter MsbA in a dozen environments

High-resolution structure determination of membrane proteins typically requires isolation from the native lipid bilayer and reconstitution into artificial membrane mimics. For this purpose, numerous d...

biorxiv.org

ABC2025 on the slopes!!! That's where the best collaboration are formed!!!