📣Join us today at 16:00 in ATV Seminar Room for the next i2 Seminar! Discover how the microbiome influences PDAC beyond what meets the eye,and learn about parvoviral features contributing to their oncosuppressive properties. ✨Talks by Sahana Asokan(AG Elinav)and Jürg Nüesch (D430)! @dkfz.bsky.social

📣 i2 Seminar on Wednesday, 9th July at 16:00 in K1/K2! Talks will be given by Ann-Katrin Schlosser (AG Riemer) & Miray Cetin (AG Hartmann) who will focus on the anti-tumor efficacy of multi-epitope therapeutic HPV vaccine, as well as modulation of breast TME along a macrophage axis!@dkfz.bsky.social

📣 Join us today at 16:00 in ATV A0.106 for the next i2 Seminar! Discover how fusion-derived epitopes can serve as T cell targets in solid tumors and gain insights into molecular characterisation of Bovine Meat & Milk Factors. ✨ Talks by Saskia Stange and Paul Oladimeji Duduyemi! @dkfz.bsky.social

📣 Next i2 Seminar is coming up on Thursday, 21st May at 16:00 in K1/K2! This time it’s all about T cells in lung cancer brain metastases and how to overcome the challenges of GMP-manufactured individualized therapies. ✨Join us for talks by Liesa-Marie Pilger and Julian Thimm! @dkfz.bsky.social

📣 i2 Seminar tomorrow, 16:00 in K1/K2! We will learn how tumor microenvironment reprogramming boosts T cell-mediated immunotherapies in pediatric cancers and explore dynamics of HBV morphogenesis in persistent infection. With Simon Krost (AG Seitz) & Aditi Dhawan (AG Seitz)! @dkfz.bsky.social

📣 i2 Seminar tomorrow (16.04) at 16:00 in ATV! Together we will explore tumor-reactive T cells in pancreatic cancer and single-cell interaction analyses for TCR discovery. Talks will be given by Stefan Zens (AG Offringa) and Felix Andres (AG Eichmüller). Make sure to join us !✨ @dkfz.bsky.social

📣 i2 seminar today (26.3) at 15:45 in ATV! From mapping immune behavior in glioblastoma to learning how APOBEC2 shapes hematopoietic cell identity—two exciting talks await in our series ✨ Join us for presentations by Dr. Davide Caredio (AG D280) and Christos Gkougkousis (AG D150)! @dkfz.bsky.social

Today, we will focus on non-cancer-cell-autonomous immunity by learning about reprogramming CAFs and optimising CAR-T cells, with the aim of promoting anti-tumour immunity. Join us at 4 pm in ATV, where talks will be given by Dr. Micaela Domingues (AG Munir) and Vincenz Buschinger (AG Buchholz)!

📣 i2 seminar on 5.2 at 16h in ATV! From ATP-driven immune evasion in myeloid leukemia to cutting-edge lipid nanoparticle strategies for engineering therapeutic T cells- two exciting talks, given by Hu Zhaoqing and Dr. Ramzi Saeed, coming up in our seminar series!✨ @dkfz.bsky.social

Join us today in the main building at 4 pm for talks given by David Vonhören and Dr. Katia Dittus who will tell us about intratumoral NK and T cell interactions in brain tumors and RadioVirotherapy for the treatment of refractory tumors. Looking forward to the exciting talks and snacks afterwards!✌🏼

📣 Last i2 seminar of the year TODAY! Kyanna Ouyang from the Puschhof Lab will present her work on host-microbe interactions in colorectal cancer! Join us for the seminar and the Christmas party afterwards! 🎄 @dkfz.bsky.social @emil-dkfz.bsky.social @jenspuschhof.bsky.social

📣 Next i2 seminar on 4.12! We will host Dr. Dr. Med. Michael Dill (Dill Lab) and Aleksandr Refeld (Binder Lab). Talks will cover how cell lineage shapes the immune landscape of the TME, and the roles of cell-autonomous vs. auto-/paracrine innate immune signaling in viral infections @dkfz.bsky.social

📣Join us today at 4 pm in ATV where we will hear two talks by Aikaterini Kadianaki (AG Heikenwälder) and Luisa Burger (AG Harbottle) who will tell us more about regulation of immunosurveillance in HCC and genetic modification of NK cells using SMAR Nanovectors. See you soon!✌🏼 @dkfz.bsky.social

📣 Next i2 seminar happening on 16th Oct! We will host Dr. Mohammad Abukhalaf from the Tenzer Lab at HI-TRON and Kassandra Hoetzel from the Wardemann Lab at DKFZ. Looking forward to discuss how to identify TCR-ligands and novel spectral flow panels for B and T cells responses! @dkfz.bsky.social

📣 Next seminar coming up this Thursday, 2.10. at 4pm! Dr. Thomas Kerzel-Gnaneswaran is a PostDoc in Ugur Sahins group at the HI-TRON in Mainz. His talk is a must-see for everyone interested in how to genetically engineer T cells in vivo! We’re already excited, see you there! @dkfz.bsky.social

Today at 4 PM, Dr. Chih-Ying Lee (Postdoctoral scientist in Delecluse Lab), will focus on the intersection between DNA damage repair and innate immune response, showing us data on how type I IFN response can interfere with the repair of DNA in B cells. See you soon in ATV! 🤓 @dkfz.bsky.social

📣 On 10.7 at 4 PM, Dr. Marten Meyer (Deputy Head, Jäger Lab) and PhD student Kilian Merz (Hartmann Lab) will present new insights into personalized immunotherapy for metastatic cancer and metabolic remodeling of neutrophils in cancer. See you there! @dkfz.bsky.social

Join us on 18.7. from 13:30 to 15:00 in the ATV seminar room (ground floor) for a guest lecture by Dr. Daniel Utzschneider (Doherty Institute) on Transcriptional and environmental regulation of T cell responses to viral infection and cancer. Cutting-edge immunology- don’t miss it! @dkfz.bsky.social

📣 i² seminars are back! Join us on June 26 at 4 PM in the DKFZ Main Building where Andreas Kienzle, a PhD student from Riemer Lab, will talk about the neoepitope discovery from blood. Beers and snacks afterwards! @dkfz.bsky.social

Join us for today’s i2 seminar at 4 PM in the ATV! We’ll dive into how microRNAs shape immune checkpoint pathways and explore links between bovine products and chronic disease & cancer. Great science, good snacks, and lively discussion await!

CoViPa studies COVID-19 pathogenesis, aiming to gain knowledge on future pandemic preparedness- and AIMM will help automate biomarker assays, advancing diagnostic and therapeutic development through high-throughput, intelligent lab automation! #CoViPa #Helmholtz #PandemicPreparedness covipa.dkfz.de

DKFZ Immunology, Infection and Cancer@dkfz-iic.bsky.social · last yr.

From space tech to pandemic science! We're excited to have been hosting the Autonomous Intelligent Mobile Manipulator (AIMM) robot (picture below) and colleagues from the DLR Robotics Institute as part of the Helmholtz CoViPa project, bringing together immunology, virology and robotics! 🤖 🦠 🧬

From space tech to pandemic science! We're excited to have been hosting the Autonomous Intelligent Mobile Manipulator (AIMM) robot (picture below) and colleagues from the DLR Robotics Institute as part of the Helmholtz CoViPa project, bringing together immunology, virology and robotics! 🤖 🦠 🧬

Exciting news! Join us in Heidelberg, June 2–3, 2025, for the CoViPa International Symposium on Pandemic Preparedness at DKFZ. Experts will share insights on COVID-19 pathogenesis and strategies for future pandemic readiness. Looking forward to welcoming you! 🔗 covipa.dkfz.de #CoViPa #Helmholtz

Researchers at the DKFZ and the Heidelberg University Hospital have discovered that the Epstein-Barr virus increases the ability of infected immune cells to migrate. In this way, the pathogen promotes its spread in the body - a potential approach for new therapies. t1p.de/g626g

How the Epstein-Barr virus promotes its spread in the body

Many people are infected with the Epstein-Barr virus (EBV), and most are unaware of it. However, EBV can sometimes cause cancer, and this pathogen also appears to play an important role in multiple sc...

t1p.de

Forschende vom @crg.eu, dem @irbbarcelona.org und dem DKFZ fanden heraus: Mit dem #Alter schrumpft das Reservoir an Blutstammzellen. Es wird zunehmend von Stammzellen dominiert, die entzündungsfördernde Immunzellen hervorbringen. t1p.de/ovqqp 👇

Wie Altern das Blutsystem von Menschen und Mäusen verändert

Das Reservoir an Blutstammzellen schrumpft mit dem Alter. Es wird zunehmend von Stammzellen dominiert, die Immunzellen hervorbringen, die mit chronischen Entzündungen in Verbindung stehen. Fast alle d...

t1p.de

Join us this week on Thursday (22nd May) for our next i2 seminar! This week it’s all about T cells in cancer!

Interested in SARS-CoV-2 and pandemic preparedness? Join the #covipa symposium on June 2/3 in Heidelberg/Germany, with keynotes by @marionkoopmans.bsky.social, @sanderlab.bsky.social, Florian Krammer, Gülsah Gabriel and Andreas Wack: indico.dkfz.de/event/1169/

International Symposium on Pandemic Preparedness

CoViPa – Virological and immunological determinants of COVID-19 pathogenesis - lessons to get prepared for future pandemics: The research network CoViPa, funded by the Helmholtz Association, is dedica...

indico.dkfz.de

Congratulations! 🎉 Michael Platten was nominated as ambassador in Germany for the ERC network! The newly selected ambassadors are part of an initiative to promote frontier research. Great news for science in Europe! @michael-platten.bsky.social @platten-lab.bsky.social @ercgrantees.bsky.social

Deutsches Krebsforschungszentrum (DKFZ)@dkfz.bsky.social · last yr.

@michael-platten.bsky.social has been selected and nominated as Ambassador for the ERC network. The @erc.europa.eu & the @ercgrantees.bsky.social launched the new Ambassadors on 28 April. This joint initiative aims to promote investment in frontier research and highlight the importance of #research.

🧬 New Paper out! Kathrin Wellach and Angelika Riemer from our department published a new highly sensitive cytotoxicity assay using live-cell imaging. With this method, epitope-specific T cells can be functionally analyzed for their cytotoxic capacity! 📄 Check it out: tinyurl.com/cytotoxicity...

Frontiers | Highly sensitive live-cell imaging-based cytotoxicity assay enables functional validation of rare epitope-specific CTLs

Many immunotherapeutic approaches aim to induce epitope-specific T-cell cytotoxicity. However, the identification—and especially the functional validation—of...

tinyurl.com

Today is the award ceremony for Franziska Blaeschke who received the Erna Brunner Prize for her work on CAR-T cell therapies to treat solid tumors! Congratulations on this achievement! @blaeschkelab.bsky.social

DKFZ Immunology, Infection and Cancer@dkfz-iic.bsky.social · last yr.

Congratulations, Dr. Franziska Blaeschke! The DKFZ/KiTZ junior group leader and UKHD assistant physician was awarded the 2024 Erna Brunner Prize (€10,000) for her groundbreaking research on CAR-T cell therapies to advance the treatment of solid tumors. 👏 More: www.kitz-heidelberg.de/en/the-kitz/...