The issue isn’t only that millions live with #Chagas disease & cutaneous #leishmaniasis. The issue is that science struggles to respond fast enough. New study shows how collaborative platforms are reshaping research: cooperation, tech transfer & shared governance. 📖 www.scielo.br/j/physis/a/N...

🌍 We’re #hiring! We are seeking an Executive Director to lead DNDi through our next phase of impact, innovation, & sustainable growth. 📌 Based in Geneva, Switzerland ✅ Full-time position – 100% 📆 Deadline: 15 September 2026 👉 Find out more and apply here: careers-dndi.icims.com/jobs/1246/ex...

Good news! @WHO recommends new treatment guidelines for #leishmaniasis. East Africa: new combo treatment is 90%+ effective, cuts injections 34→14, hospitalization 60-90→14 days. South Asia: safer PKDL options, less toxic. Read more bit.ly/4x9OYv3 #BeatNTDs @dndi.org

WHO recommends new, better and safer treatment regimens for leishmaniasis

The World Health Organization (WHO) has issued major updates to its leishmaniasis treatment guidelines, introducing a new regimen for visceral leishmaniasis (VL/kala-azar) in eastern Africa and severa...

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New method for finding drugs for #Chagas disease: www.mdpi.com/1424-8247/19... By combining chemical similarity & AI protein structure predictions, the tool correctly identified known drug targets in most tests, helping speed up drug discovery while reducing time & cost @mdpiopenaccess.bsky.social

Dengue is no longer just a tropical disease. As the climate warms, the dengue-carrying mosquito is expanding its reach to new regions. Despite this growing global threat, there is still no specific treatment for dengue. Together with our partners, we're working to change this!

What happens when equity becomes negotiable, and solidarity becomes optional? During the April 2026 Open Forum, Michelle Childs from @dndi.org reflected on what it takes to make solidarity operational. Watch the excerpt here: www.youtube.com/watch?v=eIe2... #Health #Solidarity #Bioethics

Last week, experts came together in a webinar to reflect on the last 10 years of #mycetoma progress and look at future priorities to tackle this devastating disease. If you missed it, listen to the audio recording here: www.youtube.com/watch?v=scke...

A decade of mycetoma advocacy and research (webinar audio recording)

YouTube video by Drugs for Neglected Diseases initiative (DNDi)

youtube.com

In Latin America, 2025 was marked by important progress across our R&D portfolio & access initiatives. Our Latin America Activity Reports are now available. Explore the highlights & learn about our work across the region. 🔗 Portuguese: bit.ly/relatórioDNDi2025 🔗 Spanish: bit.ly/informeDNDi2025

Join me at the Implantation Mycoses Symposium on 23rd July at #Infocus2026 as we discuss quality of life in #chromoblastomycosis, new #mycetoma findings from #Paraguay and updates on #lobomycosis. Also stop by the @dndi.org booth to learn more about our work on #NTDs

10 years ago, #mycetoma was added to @who.int's list of #NTDs. That milestone was shaped by many advocates, including students who attended the World Health Assembly & refused to let the disease go unnoticed. Here's the full story: dndi.org/stories/2026...

Annie Liang: How students’ advocacy helped bring mycetoma out of the shadows

In 2014, as an undergraduate student, Annie Liang attended the 67th World Health Assembly (WHA) as part of a youth delegation with Universities Allied for Essential Medicines (UAEM), where she and her...

dndi.org

🤝Acoziborole was made possible through a strong partnership with Sanofi, which contributed expertise in regulatory affairs, manufacturing and supply - complementing our role in bringing deep knowledge of #SleepingSickness and experience conducting clinical trials across Africa.

🎉 Our annual report is out! In 2025, we advanced work on 📋 33 projects, including 🔬 13 clinical trials in 6 disease areas, conducted across 📍 41 sites in 🌍 16 countries. To every partner and supporter standing with us: thank you 🙏 🔗 dndi.org/about/annual...

For people with #Chagas disease, it can take years to know if treatment has worked. This study in @plos.org proposes a framework for using qPCR to identify treatment failure sooner & support the development of better therapies. journals.plos.org/plosntds/art...

Consensus framework for developing a target product profile of real-time PCR in Chagas disease therapeutic monitoring

Chagas disease remains a neglected global health problem with major diagnostic and therapeutic challenges. Progression from acute to chronic infection may lead to cardiac or digestive complications in...

journals.plos.org

El diagnóstico oportuno es uno de los mayores desafíos frente a la enfermedad de Chagas. Este estudio presenta evidencia de una estrategia de tamizaje comunitaria que puede contribuir a cerrar esa brecha. 🔗Conoce los resultados→ revistas.unc.edu.ar/index.php/me...

Have you registered for the upcoming webinar session on advancing research, diagnosis, & care for people with #mycetoma? Don't miss out on the conversation! 🗓️Thursday 16 July, 2026 🕒16:00-17:15 EAT / 1:00-2:15 GMT 🔗Register here➡️ us06web.zoom.us/webinar/regi... #MycetomaAt10 #BeatNTDs

Acoziborole is the result of two decades of scientific innovation & collaboration with many partners & donors that have joined us on this long journey to fight #SleepingSickness. Hear from @drluispizarro.bsky.social, our ED, on how medical innovation can bring hope to people affected.⤵️ #1Dose1Cure

We are delighted to announce that we are part of a drug discovery project on #mycetoma supported by @novo-nordisk.bsky.social and led by @erasmusmc.bsky.social in the Netherlands. Read more here: novonordiskfonden.dk/en/news/no-e...

Africa's vulnerability during recent health emergencies highlights the need for stronger local R&D. This @naturemedicine.bsky.social comment argues for regionally coordinated hubs to drive research, development and manufacturing across Africa. www.nature.com/articles/s41...

👏 The United Nations Human Rights Council adopts for the first time a resolution on NTDs: www.who.int/news/item/07...

Historic resolution on neglected tropical diseases adopted by the United Nations Human Rights Council

Resolution 62/27 on “Human rights and neglected tropical diseases” was adopted today by the Human Rights Council (HRC) at its sixty-second session in Geneva.

who.int

We're pleased to announce that we have signed a licensing agreement with the @seruminstindia.bsky.social to support the development of what could become the world's first specific treatment for dengue. Read the press release: www.dndi.org/press-releas...

Why do some drug candidates enter cells more easily than others? This study explores how molecular shape, flexibility and internal interactions influence permeability, offering insights for designing better macrocyclic medicines. doi.org/10.1021/acs....

What Is in a Structure? Cell Permeability and Solubility of Series of Macrocycles and Linear Matched Pairs

Macrocycles are a highly interesting modality to modulate difficult-to-drug targets, but often reside in chemical space where obtaining sufficient cell permeability and solubility is challenging. We have determined permeability across Caco-2 cells, aqueous solubility and log D for four series of semipeptidic macrocycles and one series of linear matched molecular pairs. By using X-ray crystallography, NMR spectroscopy, and computational chemistry, unexpected permeability differences between series and matched pairs were explained by differences in conformational preferences that determine the formation of intramolecular interactions. Macrocycles that formed intramolecular NH–π interactions and hydrogen bonds were more permeable than matched pairs unable to form such interactions. The elevated permeability of linear compounds was concluded to result from their greater conformational flexibility, allowing them to shield amide bonds and expose nonpolar groups to a greater extent than their macrocyclic matched pairs. Solubility was less dependent on specific intramolecular interactions and was predominantly low at log D >2.5.

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It's been 10 years since @who.int recognized #mycetoma as an #NTD. Join us for a webinar as we reflect on improving diagnosis, treatment & access. 📆 16 July, 16:00 EAT Register➡️ us06web.zoom.us/webinar/regi... #MycetomaAt10

🤝 How do you use crowdsourcing to design medicines that could work against coronaviruses? In this video, Fanny Escudié, our Senior Discovery Project Manager, shows how open science, AI, and global collaboration are accelerating discovery.

Doctors say cryptococcal meningitis linked to #HIV is treatable, but access to medicines and diagnostics remains uneven where deaths are highest. Supported by @dndi.org #SciComm

Cryptococcal meningitis: Africa's neglected HIV killer

Doctors say more diagnostic testing is needed for cryptococcal meningitis, a deadly disease affecting people with HIV.

scidev.net

📣Updated statement: The ongoing Bundibugyo ebolavirus (BDBV) outbreak in DRC shows pandemic risks can't be fully anticipated, and that preparedness must extend across viral families, including rare and neglected ones. 🧵 1/4

For decades, sleeping sickness was one of the most difficult challenges that MSF doctors had to confront in Central Africa. Today, 20 years after MSF & partners created DNDi, a revolutionary single-dose treatment for this disease stands ready to be distributed throughout the continent. @msf.ca

Today, we joined 7 PDPs to launch a call for sustained EU funding for EDCTP — supporting 20+ years of Europe–Africa clinical research, capacity strengthening, and innovation for global health security. Learn more: dndi.org/publications...

🥵 Rising temperatures are bringing #dengue to Europe. In this video, Sascha van Beek, German politician & nurse, explains why dengue is no longer a distant threat and why Germany & Europe need to prepare now. 👉 Investing in dengue research & innovation is a global priority. #ClimateChange

🎧 The third episode of our podcast is out! Many of Dr Al-Yafrosi’s patients are affected by cutaneous leishmaniasis, a neglected parasitic disease that can lead to acute social stigma, particularly for women and children. 👉 Available on Spotify & Apple Podcasts: open.spotify.com/episode/0pcW...

It's been 10 years since @who.int recognized #Mycetoma as an #NTD. Join us for a webinar 'A Decade of Mycetoma Advocacy and Research: Lessons Learned and the Future' as we reflect on improving diagnosis, treatment & access. @mycetomarc.bsky.social Registration➡️ bit.ly/4f3kZP3 #MycetomaAt10

Welcome! You are invited to join a webinar: A decade of mycetoma advocacy and research: Lessons learned and the future. After registering, you will receive a confirmation email about joining the webin...

Join us on Thursday, 16 July 2026, for a webinar marking a decade since the World Health Organization (WHO) recognized mycetoma as a Neglected Tropical Disease (NTD). This event will explore the evolu...

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