Scientists are overrated when fakery is cheaply available and spread from the top. When we reward an idiot for their idiocy, they believe they are genius. www.science.org/content/arti...

Trump hits NIH with ‘devastating’ freezes on meetings, travel, communications, and hiring

Researchers facing

science.org

Cancer uses a sinister trick to evade the immune system: it hijacks T cells by transferring faulty mitochondria, weakening their ability to fight. This groundbreaking discovery reveals why some immunotherapies fail and opens new paths for treatment. www.nature.com/articles/s41...

Immune evasion through mitochondrial transfer in the tumour microenvironment - Nature

Mitochondria with mutations in their DNA from cancer cells can be transferred to T cells in the tumour microenvironment, which leads to T cell dysfunction and impaired antitumour immunity.

nature.com

Cancer uses a sinister trick to evade the immune system: it hijacks T cells by transferring faulty mitochondria, weakening their ability to fight. This groundbreaking discovery reveals why some immunotherapies fail and opens new paths for treatment. www.nature.com/articles/s41...

Immune evasion through mitochondrial transfer in the tumour microenvironment - Nature

Mitochondria with mutations in their DNA from cancer cells can be transferred to T cells in the tumour microenvironment, which leads to T cell dysfunction and impaired antitumour immunity.

nature.com

GLP-1 receptor agonists show potential beyond diabetes & obesity, reducing risks of neurocognitive disorders, cardiometabolic issues, & infections, but increase risks of gastrointestinal problems, hypotension, & kidney issues, per a large study on 175 health outcomes. www.nature.com/articles/s41...

Mapping the effectiveness and risks of GLP-1 receptor agonists - Nature Medicine

An atlas of the associations between the use of GLP-1 receptor agonists (GLP-1RAs) and 175 health outcomes reports the effectiveness and risks of GLP-1RAs compared with other antihyperglycemic medicat...

nature.com

Our new study shows that SARS-CoV-2 spike protein accumulates & persists in the body for years after infection, especially in the skull-meninges-brain axis, potentially driving long COVID. mRNA vaccines help but cannot stop it🔬🧠🦠🧵Your weekend read👇 @cellpress.bsky.social cell.com/cell-host-mi...

Persistent SARS-CoV-2 spike protein in the skull-meninges-brain axis may drive long COVID neurological symptoms. Induces neuroinflammation, proteome changes, & worsens outcomes in stroke/brain injury models. Vaccination reduces but doesn't eliminate accumulation. #MedSky 🧪

Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19

SARS-CoV-2 infection can lead to long-lasting neurological sequelae, but underlying mechanisms are unclear. Rong et al. report that SARS-CoV-2 spike protein persists in the skull-meninges-brain axis, ...

cell.com

🚨 The injectable drug benralizumab significantly reduces asthma and COPD flare-ups by targeting eosinophils, a type of white blood cell involved in inflammation. This treatment decreases the need for hospitalization by 30%. Can be a game changer. #Medsky 🧪 www.news-medical.net/news/2024112...

New injection treatment could be a game-changer for people with asthma and COPD

An injection given during some asthma and COPD attacks is more effective than the current treatment of steroid tablets, reducing the need for further treatment by 30%.

news-medical.net

Researchers found that to address the epidemic of mental ill health among HCPs, workers needed: Targeted MH interventions Hot food Rest areas/lockers Free parking Essentially staff just need to be valued & treated like human beings. Rocket science it is not. evidence.nihr.ac.uk/alert/system...

NHS staff psychological wellbeing: system-level changes needed

System-level changes such as improvements in working conditions are essential in order to improve the psychological wellbeing of NHS staff.

evidence.nihr.ac.uk

Déjà vu! Atleast adhere to the advice this time, in time.

WHO calls for stronger surveillance of H5N1 bird flu among animals

A World Health Organization official on Thursday called for stronger surveillance in animals for evidence of infection with H5N1 bird flu in order to curb its spread.

reuters.com

Between 2013-2021, cervical cancer mortality in U.S. women under 25 dropped by 62%, thanks to widespread HPV vaccination. Yet, vaccination rates fell to 75.9% in 2023. Let's prioritize protecting the next generations. Vaccines Rock no matter what the anti vaxxers claim falsely. #Medsky 🧪

JAMA@jama.com · 2y ago

Cervical cancer mortality in US women younger than 25 years significantly declined between 2016 and 2021, likely due to the widespread adoption of HPV vaccination. ja.ma/4i9ghPC

FYI. In case you plan to 'warn' your policy makers by making some noise about this. They should be proactive this time, before it is too late. H5N1 virus has been spreading in mammals across many countries, and has had human cases too. www.independent.co.uk/news/health/... #Medsky 🧪

Experts say bird flu is more widespread than we think: ‘We are in a soup of virus’

“We are in a soup of virus. I mean, there’s virus everywhere around us at this point,” one scientist said

independent.co.uk

New study on COVID-19 vaccines for kids 6-24 months: Mild reactions like fussiness (30%) and fever (14%) common, severe cases rare (0.3%). Moderna had slightly higher reaction rates than Pfizer. Vaccines remain SAFE & effective for young children. #Medsky 🧪 jamanetwork.com/journals/jam...

Current risk for human transmission is low , but the way policy makers are sleeping over the spread , this might change. We can't be exposing the world to yet another fast spreading deadly virus.

Avian Influenza A(H5) Outbreak | Center for Outbreak Response Innovation

cori.centerforhealthsecurity.org

H5N1 has spread to many countries. This is how it can spread e.g. from cows to humans on a dairy farm. As always Govts won't act proactively to save the spread so we need to spread the awareness. #Medsky 🧪

Great news that a kit can detect the H5N1 in under three hours. Can differentiate from other avian viruses too. Otherwise it would take a few days. Can be really helpful in prevention and spread of H5N1. 🧪 #MedSky

Breakthrough Diagnostic Kit Detects H5N1 Avian Flu in Just 3 Hours

The Steadfast diagnostic kit, developed by DxD Hub, NIES, and A*STAR BII, rapidly detects and distinguishes H5N1 AIV strains, improving outbreak response and global pandemic readiness. The Diagnostics...

search.app

Scientists developed a malaria vaccine using mosquito bites! 🦟 Modified malaria parasites boost immunity without causing disease. In trials, 89% of participants avoided malaria. Minimal side effects. A potential game-changer for global malaria control. www.nature.com/articles/d41... #MedSky

This malaria vaccine is delivered by a mosquito bite

Bites from insects infected with modified malaria parasites boosted immunity and stopped people from contracting the disease.

nature.com

H5N1 has mutated. No human to human transmission detected yet. Can mutate to acquire that hence the concerns. Causes conjunctivitis and severe lung issues.Older vaccines might help but further research on vaccines ongoing. www.nature.com/articles/d41...

Why a teenager’s bird-flu infection is ringing alarm bells for scientists

A strain of avian influenza is showing signs of adaptation to human hosts, but there is no evidence that it can transmit from person to person.

nature.com

COVID is over, right? It is still 'ripping through ' our children n their teachers. 😡 No Cap.

What to make of the rise of the wellbeing sick day

New data shows staff 'wellbeing' absences are rising, as a report warned of 'disturbingly high' stress

schoolsweek.co.uk

Avg hospital stay for COVID in Scotland. Policy makers have stopped caring about the virus and it's impact on the people, but the virus has not stopped it's job. Thanks to efforts like this graph from @1goodtern.bsky.social that we can still get an overview #MedSky

Death rates continue to be much higher in the unvaccinated than the vaccinated for COVID. Not surprising but worth highlighting, repeatedly.

H5N1 has been on the move. Spreading. No one wants to hear the P words, but it has the potential for harming us en mass. Make some noise so that our policy makers wake up well in time than the 'last time'.

Only if rationality was the basis of our key decisions, we could easily avoid wars, idiotic policies and lot of troubles of long COVID. Only if.

Tirzepatide reduces the risk of cardiovascular death or worsening heart failure and improves health status in patients with HFpEF and obesity. Vs placebo. www.nejm.org/doi/full/10....

Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity | NEJM

Obesity increases the risk of heart failure with preserved ejection fraction. Tirzepatide, a long-acting agonist of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor...

nejm.org

COVID hastens ageing. Just that fact should be enough for us to keep protecting ourselves against it. 🧪