Thrilled to see our work featured on the cover of Molecular Cell. The image is an electron micrograph of an i-loop, the DNA structure we propose as a source of eccDNA formation. Almost like catching circular DNA formation in the act. #eccDNA #CancerResearch #GenomeInstability #DNARepair

How do cancer-associated eccDNAs arise? Our work shows that single-strand DNA damage in repetitive sequences can trigger i-loop formation and eccDNA generation. What started at telomeres may reflect a much broader principle across the genome and help explain how ecDNA may emerge in cancer. 1/2

Aiutateci a fare la differenza: sostenete la ricerca e correte con noi. #Maratona #AIRC #Ricerca #Oncologica www.retedeldono.it/iniziativa/y...

This week Dr. Doksani will join Social DNAing to discuss telomere biology! Please note the US is now in summer saving time. Check you local time! www.cancer.columbia.edu/research/pro...

Another great science appointment is coming up with @nitikataneja.bsky.social and @doksanilab.bsky.social! Join us live on Tuesday, February 3rd at 5pm (Rome) / 11am (NYC). Zoom link: uniroma1.zoom.us/j/95149984403 Register here to stay in the loop: docs.google.com/forms/d/e/1F...

Telomere Community 🧬 Can't wait for the new CSHL Monograph? Our review on unusual structure at Telomeric repeats is now live on Cold Spring Harbor Perspectives! Grab a few free PDFs here: cshperspectives.cshlp.org/cgi/reprint/... #CHSL #AcademicSky #Science @ezeta.bsky.social @cshlnews.bsky.social