Delighted to give a talk at the wonderful Cambridge Center for Myelin Repair annual symposium in Cambridge, UK. Truly fantastic conference and an amazing community. Thank you to Thora Karadottir and @mssocietyuk.bsky.social for organising!
Mike Dolan
@dolanmjg.bsky.social
Assistant Professor @ Trinity College Dublin Neuroimmunology | CNS disease and repair. 🇮🇪🇪🇺🏳️🌈 https://dolanlab-tcd.com/
How does the brain repair myelin after injury? We mapped the full cellular choreography of white matter repair using snRNA-seq + Slide-seqv2, uncovering a type I interferon-driven glial program that recruits lymphocytes to promote remyelination. www.biorxiv.org/content/10.1... Details below 👇
Spatiotemporal Analysis of Remyelination Reveals a Concerted Interferon-Responsive Glial State That Coordinates Immune Infiltration
Remyelination, the process by which axons are re-encased in myelin after injury, is a critical step in restoring brain function, yet the dynamics from initial injury to repair remain poorly characteri...
biorxiv.org
Imaging these astrocytes on the surface of cleared brains was a blast!
UK Dementia Research Institute@ukdri.ac.uk · last yr.A new study led by @philiphasel.bsky.social reveals the unique genetic profile of astrocytes that form the glia limitans superficialis (GLS), the thin layer of cells that covers the brain and spinal cord 🧠 Dr Hasel spoke to @thetransmitter.bsky.social about his work⬇️