Donat Wulf

@donat.bsky.social

fascinated by gene regulatory networks. Postdoc at UC Berkeley #R #python https://scholar.google.com/citations?user=sgykqjgAAAAJ&hl=de

How do transcription factors bind DNA strongly, and in a switch like manner, while remaining sequence specific? Our new paper on a canonical plant TF suggests the answer is a previously underappreciated assembly state: transcription factor nanoclusters. www.science.org/doi/10.1126/...

Nanoclustering of a plant transcription factor enables strong yet specific DNA binding

Transcription factor nanoclusters balance the DNA binding trade-off between weakly binding oligomers and nonspecific condensates.

science.org

Excited to introduce Auxenochlorella as a new algal reference organism for fundamental plant science and bioengineering. A paper in two parts: a genetic toolkit for site-specific genomic manipulation, paired with the most unusual genome I’ve ever worked on academic.oup.com/plcell/artic...

Targeted genetic manipulation and yeast-like evolutionary genomics in the green alga Auxenochlorella

Auxenochlorella, green algae shaped by evolutionary forces acting on vegetative diploids, are amenable to discovery research and bioengineering via efficie

academic.oup.com