Doris Wang
@doriswang.bsky.social
Neurosurgeon-scientist studying how brains walk the walk. Neural interfaces, devices, oscillations, and toddler chase dynamics. Balancing beta bursts and bedtime stories. 📍UCSF | 🧠⚡️🚶🏻♂️ | Views my own (but likely statistically significant)
New on Stimulating Brains: @doriswang.bsky.social on adaptive DBS synchronized with the moment-by-moment rhythm of walking—and what it could mean for gait and falls in Parkinson’s disease. 🎧 stimulatingbrains.org/82-doris-wan... #DeepBrainStimulation #AdaptiveDBS #ParkinsonsDisease #Neurosurgery
@neurosurgucsf.bsky.social researchers developed a “smart” implant for Parkinson’s patients that adjusts stimulation in real time as they walk, improving gait & reducing falls. It's "an important step toward a new generation of brain therapies," @doriswang.bsky.social says. https://ucsfh.org/4uyGOuF
A smarter brain implant offers new hope for Parkinson's patients
Researchers at UCSF have taken a step toward a long-sought goal in treating Parkinson's disease: a brain implant that can adapt to a patient's movements in real time.
ucsfh.org
A randomized crossover study shows that gait-phase synchronized adaptive deep brain stimulation is feasible, safe, and reduces falls compared to continuous stimulation in Parkinson’s disease. @doriswang.bsky.social @neurosurgucsf.bsky.social
Adaptive deep brain stimulation for dynamic gait control in Parkinson’s disease: a randomized feasibility trial - Nature Medicine
A randomized crossover study shows that gait-phase-synchronized adaptive deep brain stimulation is feasible and safe, and reduces falls compared to continuous stimulation in Parkinson’s disease.
dlvr.it
Super excited to share our new study showing that deep brain stimulation (DBS) can be synchronized to each step a person takes and improve walking in Parkinson’s disease patients!
UCSF Neurosurgery@neurosurgucsf.bsky.social · 2mo agoNew in @natmed.nature.com, work by @doriswang.bsky.social shows that distinct left- and right-leg swing biomarkers can drive DBS that changes on a sub-second timescale with each step. A major advance toward movement-driven, precision-timed neuromodulation for Parkinson’s disease. 🧠📈 rdcu.be/fopFJ
Super excited to share our new paper: At-home movement state classification using totally implantable cortical-basal ganglia neural interface | Science Advances www.science.org/doi/10.1126/...
At-home movement state classification using totally implantable cortical-basal ganglia neural interface
Chronic at-home neural recordings in Parkinson’s disease reveal personalized biomarkers that accurately classify walking state.
science.org
High-intensity focused ultrasound (HIFU) is an incision-less surgical procedure used to treat essential tremor by lesioning the brain pathway involved with tremor generation. @ucsfhealth.bsky.social neurosurgeon @doriswang.bsky.social explains that this leads to lasting tremor reduction.
Great talks and even more interesting and engaging discussion! Fantastic start to the think tank!
Michael Okun@michaelokun.bsky.social · 11mo agoDBS Think Tank Scientific Sessions start on zoom at 1:00PM as soon as Nobel Laurette Stanley Prusiner finishes his talk and takes questions. We are off to a great start. Here are the first two sessions for today in case you are interested in listening in. @sfn.org @parkinsondotorg.bsky.social
Super proud and excited to share our preprint. www.medrxiv.org/content/10.1...
Adaptive deep brain stimulation timed to gait phase improves walking in Parkinson's disease
Gait dysfunction in Parkinson's disease (PD) is a major source of disability and is often resistant to traditional deep brain stimulation (DBS). Here, we report a novel neuromodulation paradigm, gait-...
medrxiv.org
Thanks you so much for inviting me to be a part of this fantastic conference! I learned so much and am beyond excited for our field!
Swathi Kiran@Center for Brain Recovery at BU@swathikiran.bsky.social · last yr.Day 1 of the 🧠Neuroscience of the Everyday World Conference included talks from notable researchers and industry experts from around the world, discussing topics of #neuroprosthetics #neuromodulation and #neurotechnology.
We’re honored to be named among the top two neurosurgery programs nationwide and the Best in the West by @usnews.com! 🎉 It's a privilege caring for our patients and their families, and we thank our entire team for hard work and dedication. @ucsfhealth.bsky.social www.ucsfhealth.org/lp/us-news-2...
A new study led by @doriswang.bsky.social's lab developed a systematic way to quantify key aspects of gait in patients with #Parkinsons and used machine learning to identify personalized deep brain stimulation (DBS) settings to improve walking: www.ucsf.edu/news/2025/07... @ucsfhealth.bsky.social 🧠📈
Lab party! Thanks to all these amazing, hardworking, compassionate geniuses for making science fun!
Can we reboot walking after Parkinson's disease DBS? Can AI teach deep brain stimulation devices to help people 'walk the walk?' A new study by Wang says MAYBE. Using personalized data-driven models, they optimized DBS for walking. @parkinsondotorg.bsky.social #parkinson @ucsfhealth.bsky.social
Very excited to share our newest publication on identifying neurophysiological signatures of improved gait using bidirectional DBS devices!
UCSF Neurosurgery@neurosurgucsf.bsky.social · last yr.New in npj Parkinson's Disease, @doriswang.bsky.social's lab presents an AI approach for identifying personalized deep brain stimulation (DBS) settings to improve walking. The findings lay the groundwork for adaptive DBS systems that adjust in real-time: www.nature.com/articles/s41... 🧠📈 🧪
Interested in human brain function and neuroimaging during natural real-world activities? Learn more from our amazing speakers and present your own work at the Neuroscience of the Everyday World Conference. Registration & abstract submission is now open: neuroscienceeverydayworld.org/conference-2...
Very much looking forward to our speakers: @maryamshanechi.bsky.social, @hugospiers.bsky.social, Marom Bikson, @jenpitt.bsky.social, Mary Czerwinski, @peabody124.bsky.social, @dpferris.bsky.social, @sladouce.bsky.social, Matthew Rizzo, @c-rothkopf.bsky.social, @doriswang.bsky.social, Ying Choon Wu
Very excited to share our latest preprint. Using implanted DBS devices with at home wearable monitors, we were able to identify gait state in the natural environment based on cortical and basal ganglia neural signature: www.medrxiv.org/content/10.1...
At-Home Movement State Classification Using Totally Implantable Bidirectional Cortical-Basal Ganglia Neural Interface
Movement decoding from invasive human recordings typically relies on a distributed system employing advanced machine learning algorithms programmed into an external computer for state classification. ...
medrxiv.org
To the stranger who paid for our lunch at Kona airport because I didn’t have a credit card on me (getting too used to tap to pay), thank you from the bottom of my heart and my toddlers’ growling stomachs. I will always remember your kindness and pay it forward! #humanity #payitforward #kindness
Excited to share our new preprint. We recorded field potentials from the motor/premotor cortices and pallidum of people with Parkinson’s disease as they performed a gait initiation task to understand the cortico-pallidal network dynamics that underlie this action: www.medrxiv.org/content/10.1...
Pallidal and motor cortical interactions determine gait initiation dynamics in Parkinson's disease
Gait initiation is a fundamental human task, requiring one or more anticipatory postural adjustments (APA) prior to stepping. Deviations in amplitude and timing of APAs exist in Parkinson's disease (P...
medrxiv.org
Completed our 100th focused ultrasound treatment! It truly takes a village and a collaborative effort to make it possible. Go team and here’s to many more! #fus #hifu #neurosurgery #tremor
Masters debate in a chateau! Amazing talks, colleagues, and inspiring innovation. So great to be back in Paris even just for a day!
